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Publications

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants

Crouch DJM. and Bodmer WF., (2020), Proceedings of the National Academy of Sciences, 202005634 - 202005634

Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing.

Bodmer WF. and Crouch DJM., (2020), Journal of theoretical biology, 489

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells.

Inshaw JRJ. et al, (2020), Diabetes care, 43, 169 - 177

Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Ferreira RC. et al, (2019), Frontiers in Immunology, 10

Genetics of the human face: Identification of large-effect single gene variants

Crouch DJM. et al, (2018), Proceedings of the National Academy of Sciences, 115, E676 - E685

Statistical aspects of evolution under natural selection, with implications for the advantage of sexual reproduction

Crouch DJM., (2017), Journal of Theoretical Biology, 431, 79 - 86

Extending non-negative matrix factorisation to 3D registered data

Koppen WP. et al, (2016), 2016 International Conference on Biometrics (ICB)

Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancer

Yarnall JM. et al, (2013), Cancer Epidemiology, 37, 324 - 329

REGENT: a risk assessment and classification algorithm for genetic and environmental factors

Crouch DJM. et al, (2013), European Journal of Human Genetics, 21, 109 - 111

Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs

Crouch DJM. and Weale ME., (2012), European Journal of Human Genetics, 20, 1283 - 1289

OC-168 Towards individualised risk prediction for crohn's disease

Taylor KM. et al, (2012), Gut, 61, A72.2 - A72

Genes predict village of origin in rural Europe

O'Dushlaine C. et al, (2010), European Journal of Human Genetics, 18, 1269 - 1270

Include forthcoming?