Publications

Assessment of the causal relevance of ECG parameters for risk of atrial fibrillation: A mendelian randomisation study

Gajendragadkar PR. et al, (2021), PLOS Medicine, 18, e1003572 - e1003572

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2021)

Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity

Gilchrist JJ. et al, (2021)

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia.

Wiessner M. et al, (2021), Brain : a journal of neurology

Design and rationale of the EMPA-VISION trial: investigating the metabolic effects of empagliflozin in patients with heart failure.

Hundertmark MJ. et al, (2021), ESC Heart Fail

LSE-Lancet Commission on the future of the NHS: re-laying the foundations for an equitable and efficient health and care service after COVID-19.

Anderson M. et al, (2021), Lancet (London, England)

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.

Datoo MS. et al, (2021), Lancet

Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells

Artibani M. et al, (2021), JCI Insight

Double-jeopardy: scRNA-seq doublet/multiplet detection using multi-omic profiling

Sun B. et al, (2021), Cell Reports Methods, 100008 - 100008

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes.

Eyres M. et al, (2021), Gastroenterology

A titan of Cardiovascular Research: Professor Peter Sleight (1929–2020)

Channon KM. and Watkins H., (2021), Cardiovascular Research, 117, e64 - e66

Small-molecule inhibitors of carboxylesterase Notum

Zhao Y. et al, (2021), Future Medicinal Chemistry

A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions

Figtree GA. et al, (2021), Circulation

FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer.

Thibord F. et al, (2021), J Thromb Haemost

CryoET structures of immature HIV Gag reveal six-helix bundle.

Mendonça L. et al, (2021), Communications biology, 4

SARS-CoV-2 within-host diversity and transmission

Lythgoe KA. et al, (2021), Science, 372, eabg0821 - eabg0821

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.

Schuller M. et al, (2021), Science advances, 7

A call to action for new global approaches to cardiovascular disease drug solutions

Figtree GA. et al, (2021), European Heart Journal

Clinical, neuroimaging and molecular spectrum of TECPR2-associated hereditary sensory and autonomic neuropathy with intellectual disability.

Neuser S. et al, (2021), Human mutation

Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial.

Emary KRW. et al, (2021), Lancet, 397, 1351 - 1362

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