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Publications

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.

Nelson L. et al, (2020), Nature communications, 11

Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma.

Fairfax BP. et al, (2020), Nature medicine, 26, 193 - 199

Artemisinin-resistant malaria parasites show enhanced transmission to mosquitoes under drug pressure

Witmer K. et al, (2020)

The guidance receptor plexin D1 is a mechanosensor in endothelial cells.

Mehta V. et al, (2020), Nature, 578, 290 - 295

Clinical significance of TP53, BIRC3, ATM and MAPK-ERK genes in chronic lymphocytic leukaemia: data from the randomised UK LRF CLL4 trial.

Blakemore SJ. et al, (2020), Leukemia

Genomic diversity affects the accuracy of bacterial single-nucleotide polymorphism–calling pipelines

Bush SJ. et al, (2020), GigaScience, 9

Pan-cancer analysis of whole genomes

(2020), Nature, 578, 82 - 93

Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy.

Mazzarotto F. et al, (2020), Circulation, 141, 387 - 398

Mechanical Regulation of Protein Translation in the Cardiovascular System

Simpson LJ. et al, (2020), Frontiers in Cell and Developmental Biology, 8

Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.

Thézénas M-L. et al, (2020), Sci Rep, 10

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice

Sachse G. et al, (2020), Wellcome Open Research, 5, 15 - 15

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.

Toepfer CN. et al, (2020), Circulation

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.

Ast J. et al, (2020), Nature communications, 11

Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank.

Du H. et al, (2020), Diabetologia

Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing.

Bodmer WF. and Crouch DJM., (2020), Journal of theoretical biology, 489

Colocalization highlights genes in hypothalamic–pituitary–gonadal axis as potentially mediating polycystic ovary syndrome risk

Censin J. et al, (2020)

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Shah S. et al, (2020), Nat Commun, 11

Hyper-acute cardiovascular magnetic resonance T1 mapping predicts infarct characteristics in patients with ST elevation myocardial infarction.

Alkhalil M. et al, (2020), Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 22

Glutathione facilitates enterovirus assembly by binding at a druggable pocket.

Duyvesteyn HME. et al, (2020), Communications biology, 3

Identification of antigens presented by MHC for vaccines against tuberculosis.

Bettencourt P. et al, (2020), NPJ Vaccines, 5

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