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Publications

A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function

Grotz AK. et al, (2019), Wellcome Open Research, 4, 150 - 150

Reply: CMR Assessment of Myocyte Disarray in HCM: Matching Another Piece in the Puzzle

Ariga R. et al, (2019), Journal of the American College of Cardiology, 74

A structure-based rationale for sialic acid independent host-cell entry of Sosuga virus

Stelfox AJ. and Bowden TA., (2019), Proceedings of the National Academy of Sciences, 201906717 - 201906717

A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.

Douglas G. et al, (2019), Cardiovasc Res

Genetic modification of primary human B cells to model high-grade lymphoma.

Caeser R. et al, (2019), Nature communications, 10

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Tin A. et al, (2019), Nat Genet

Dual quantitative coronary angiography accurately quantifies intracoronary thrombotic burden in patients with acute coronary syndrome: Comparison with optical coherence tomography imaging

Vergallo R. et al, (2019), International Journal of Cardiology, 292, 25 - 31

Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification.

Kleeman SO. et al, (2019), Gut

Translational genomics and precision medicine: Moving from the lab to the clinic

Zeggini E. et al, (2019), Science, 365, 1409 - 1413

Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells.

Inshaw JRJ. et al, (2019), Diabetes Care

Impact of Suture Type on Erosion Rate After Laparoscopic Ventral Mesh Rectopexy: A Case-Matched Study.

Tejedor P. et al, (2019), Dis Colon Rectum

A molecular barcode and online tool to identify and map imported infection with Plasmodium vivax

Trimarsanto H. et al, (2019)

Analysis of the B cell receptor repertoire in six immune-mediated diseases

Bashford-Rogers RJM. et al, (2019), Nature

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated with Cardiac Morphogenesis and Heart Failure Development.

Aung N. et al, (2019), Circulation

Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage.

Glaire MA. et al, (2019), Br J Cancer

Serial Anti–Myelin Oligodendrocyte Glycoprotein Antibody Analyses and Outcomes in Children With Demyelinating Syndromes

Waters P. et al, (2019), JAMA Neurology

The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism.

Rudolf AF. et al, (2019), Nat Chem Biol

Whole genome sequencing identifies putative associations between genomic polymorphisms and clinical response to the antiepileptic drug levetiracetam

Vavoulis DV. et al, (2019)

Marked variation in heritability estimates of left ventricular mass depending on modality of measurement.

Nethononda RM. et al, (2019), Scientific reports, 9

TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.

Leng T. et al, (2019), Cell Rep, 28, 3077 - 3091.e5

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