Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis
Duarte S., Woll PS., Buza-Vidas N., Chin DWL., Boukarabila H., Luís TC., Stenson L., Bouriez-Jones T., Ferry H., Mead AJ., Atkinson D., Jin S., Clark S-A., Wu B., Repapi E., Gray N., Taylor S., Mutvei AP., Tsoi YL., Nerlov C., Lendahl U., Jacobsen SEW.
Key Points Canonical Notch signaling is dispensable for steady-state and posttransplantation myelopoiesis, as well as stress erythropoiesis. Key lineage regulators and Notch target genes are expressed independent of canonical Notch signaling in myelo-erythropoiesis.