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Complications of percutaneous coronary intervention include in-stent restenosis (ISR) and in-stent thrombosis (IST) which have different underlying pathophysiological processes and different treatment strategies. ISR is primarily due to excessive neointimal growth and occurs in 20-30% of bare-metal stents (BMS). Drug-eluting stents (DES) have decreased the rates of ISR (< 10%), but are potentially associated with increased IST related to delayed arterial healing and stent strut exposure. ISR of BMS typically occurs within 6 months of stent deployment. IST usually occurs within 12 months of DES deployment. We present a case of focal ISR and IST within the same BMS, confirmed with intravascular ultrasound, 5 years after deployment in a saphenous vein graft.

Type

Journal article

Journal

The Journal of invasive cardiology

Publication Date

12/2007

Volume

19

Pages

E369 - E371

Addresses

Department of Cardiology, Level 2, John Radcliffe Hospital, Headley Way, Headington, Oxford, Oxfordshire OX3 9DU, United Kingdom. larryponnuthurai@ googlemail.com

Keywords

Saphenous Vein, Humans, Coronary Restenosis, Myocardial Infarction, Graft Occlusion, Vascular, Coronary Angiography, Ultrasonography, Interventional, Thrombolytic Therapy, Coronary Artery Bypass, Blood Vessel Prosthesis Implantation, Follow-Up Studies, Stents, Time Factors, Middle Aged, Male, Angioplasty, Balloon, Coronary