Gang Zhang
Post-doctoral researcher
Work summary
I am working on a project to study meiotic recombination at the individual level. Although great efforts have been made in this field globally, comprehensive knowledge of recombination has not been achieved. The aim of project is to obtain much better genomic information from isolated sperms cells and then to investigate the landscape of recombination within individuals.
Recent publications
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Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary
Journal article
Davies B. et al, (2021), Molecular Biology and Evolution
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ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair
Journal article
Wells D. et al, (2020), eLife, 9
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ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair
Journal article
Wells D. et al, (2019)
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Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm
Journal article
Hinch AG. et al, (2019), Science, 363, eaau8861 - eaau8861
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Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice
Journal article
Davies B. et al, (2016), Nature, 530, 171 - 176