Single Cell Genomics Computational Biologist
Charlotte joined the Dendrou group in the WHG in March 2020. She is a computational biologist who specialises in the analysis of single cell experiments. Her post is funded as part of the Human Immune Discovery Initiative https://www.immunology.ox.ac.uk/human-immune-discovery-initiative.
Previously, Charlotte worked at the WIMM researching cancer-specific T cells with Tao Dong and Hashem Koohy. Her work focused on integrating TCR repertoire information with gene expression in order to identify cancer specific subsets of T cells.
Prior to that, Charlotte achieved her PhD from the University of Warwick. Unlike her current research into human immunity, her PhD research focussed on plant immunity. Her thesis "Cell-type specific transcriptomics of immunity in Arabidopsis thaliana roots" was supervised by Professor Patrick Shafer and Dr Sascha Ott.
ORCID ID: https://orcid.org/0000-0001-8212-9542
Regulation of Cell Type-Specific Immunity Networks in Arabidopsis Roots
Rich-Griffin C. et al, (2020), The Plant Cell, 32, 2742 - 2762
Single-Cell Transcriptomics: A High-Resolution Avenue for Plant Functional Genomics
Rich-Griffin C. et al, (2020), Trends in Plant Science, 25, 186 - 197
Epigenome and transcriptome landscapes highlight dual roles of proinflammatory players in a perinatal model of white matter injury
Schang A-L. et al, (2018)
Cell type identity determines transcriptomic immune responses in Arabidopsis thaliana roots
Rich C. et al, (2018)