We are a research group based at Oxford University’s Department of Statistics and at the Wellcome Centre for Human Genetics, working at the intersection of computer science, statistics, and genetics. We develop methods to enable new types of analyses in statistical and population genetics, with a particular interest in problems that involve modeling and inference in large genomic datasets. Specific areas of research include:
- Reconstructing past demographic events using genetic data (migration, expansion/contraction of populations).
- Studying evolutionary parameters in the human genome (natural selection, mutation/recombination rates).
- Studying the heritability and genetic architecture of complex traits (nature vs nurture).
- Detecting disease-causing variation in the human genome (association).