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Current vacancies

Thank you for your interest in the Knight group's research work.  Currently we have one position available, please see below.


Research Assistant in Functional Genomics of Sepsis
The Wellcome Centre for Human Genetics, Roosevelt Drive, Old Road Campus, Oxford, OX3 7BN
We are seeking to appoint a Research Assistant in Functional Genomics of Sepsis to join an established team with a track record of innovation and high impact research in the functional genomics of immunity led by Professor Julian Knight at the Wellcome Centre for Human Genetics, Nuffield Department of Medicine.
We seek a highly motivated, organised and proactive individual who will benefit from the exceptional research environment at WHG. You will play a key role in an exciting research programme to investigate drivers of extremes of immune response to infection and the individual patient sepsis response. Transcriptomics can be used to define specific sepsis disease subphenotypes based on gene expression signatures in peripheral blood, and in particular to identify patients with evidence of specific immune dysfunction who have the worst outcomes. The ability to distinguish such patients provides a timely opportunity to progress towards a precision medicine approach to managing sepsis.
You will be responsible for managing the ongoing sample collection, delivering cell culture and cell purification work together with cloning, sequencing and general molecular biology. You will also play a role in the application of immunological assays and cutting-edge genomic approaches including single cell -omics. You will have a degree in biology, genetics, immunology or related field and a demonstrable interest in the research described here. You will also have experience in standard tissue culture and molecular biology techniques as well as having demonstrable high level of communication skills, both written and oral, and the ability to organize and prioritise work to efficiently deliver results to the required standard and to an agreed schedule. You will be motivated by a stimulating and ambitious research environment with a desire to deliver high quality cutting-edge science and work in a laboratory offering the opportunity for career development and acquiring new expertise.
Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application.  Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.
This position is offered full time on a fixed term contract for 12 months in the first instance and is funded by MRC and Wellcome Trust.
Only applications received before 12 midday on 19 July 2022 will be considered. Please quote 158947 on all correspondence.
Contact Person : Irene Katusiime Vacancy ID : 158947
Contact Phone : 0186587678 Closing Date & Time : 19-Jul-2022 12:00
Pay Scale : STANDARD GRADE 6 Contact Email :
Salary (£) : Salary in range £29,614 - £33,309 per annum
Click on the link(s) below to view documentsFilesize
158947-Research Assistant in Functional Genomics of Sepsis job description.pdf 858.1

Other opportunities

Graduate students interested in potentially joining the lab to study for a DPhil are encouraged to contact Julian Knight. A variety of funding opportunities are available including 
NDM Doctoral Prize Studentships and the Wellcome Trust 4 year PhD programmes in Genomic Medicine and Statistics and Infection, Immunity and Translational Medicine. Funding for clinicians includes the 3 year Wellcome Trust Training Fellowship Programme for Clinicians in Basic Sciences.