Redefining clinical practice through spatial profiling: a revolution in tissue analysis.
Journal article
Mulholland EJ. and Leedham SJ., (2024), Annals of the Royal College of Surgeons of England, 106, 305 - 312
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Journal article
Malla SB. et al, (2024), Nat Genet
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Journal article
Beach C. et al, (2023), The Journal of clinical investigation, 133
Poor diagnostic reproducibility in the identification of non-conventional dysplasia in colitis impacts the application of histological stratification tools.
Journal article
Nasreddin N. et al, (2023), Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Virtual alignment of pathology image series for multi-gigapixel whole slide images.
Journal article
Gatenbee CD. et al, (2023), Nature communications, 14
β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer.
Journal article
Suzuki T. et al, (2023), Cancer immunology research
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Journal article
Flanagan DJ. et al, (2023), Nature Communications, 14
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Journal article
Flanagan DJ. et al, (2022), Nature Communications, 13
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Journal article
Gil Vazquez E. et al, (2022), Cell stem cell, 29
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Journal article
Cañellas-Socias A. et al, (2022), Nature, 611, 603 - 613
Homeostasis limits keratinocyte evolution.
Journal article
Schenck RO. et al, (2022), Proc Natl Acad Sci U S A, 119
The Emerging Era of Personalised Medicine in Advanced Colorectal Cancer.
Journal article
Wu CW. et al, (2022), Journal of gastroenterology and hepatology
Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data.
Journal article
Fisher NC. et al, (2022), Clinical cancer research : an official journal of the American Association for Cancer Research
Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.
Journal article
Hashimoto T. et al, (2022), British journal of cancer
Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture
Preprint
Vazquez EG. et al, (2022)
Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Journal article
Corry SM. et al, (2022), Gut
Immunosuppressive niche engineering at the onset of human colorectal cancer.
Journal article
Gatenbee CD. et al, (2022), Nat Commun, 13
Gattaca: Base pair resolution mutation tracking for somatic evolution studies using agent-based models.
Journal article
Schenck RO. et al, (2022), Molecular biology and evolution
Germline variant testing in Serrated Polyposis Syndrome.
Journal article
Murphy A. et al, (2022), Journal of gastroenterology and hepatology
The molecular subtyping resource (MouSR): a user-friendly tool for rapid biological discovery from transcriptional data.
Journal article
Ahmaderaghi B. et al, (2022), Disease models & mechanisms