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Publications

Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis

Kwok AJ. et al, (2023), Nature Immunology, 24, 767 - 779

CD56bright natural killer cells preferentially kill proliferating CD4+ T cells

Lee M. et al, (2023), Discovery Immunology, 2

HLA-DQβ57, anti-insulin T cells and insulin mimicry in autoimmune diabetes

García AR. et al, (2022)

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Trzupek D. et al, (2022), Wellcome Open Research, 6, 149 - 149

Identification of deleterious neutrophil states and altered granulopoiesis in sepsis

Kwok AJ. et al, (2022)

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58

An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease

Peng Y. et al, (2022), Nature Immunology, 23, 50 - 61

Interferon-Gamma–Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis

Sasson SC. et al, (2021), Gastroenterology, 161, 1229 - 1244.e9

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Trzupek D. et al, (2021), Wellcome Open Research, 6, 149 - 149

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Trzupek D. et al, (2021)

CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

Arroyo Hornero R. et al, (2020), Communications Biology, 3

Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Ferreira RC. et al, (2019), Frontiers in Immunology, 10

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

Trzupek D. et al, (2019)

The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus

Oliveira JJ. et al, (2018), Arthritis Research & Therapy, 20

TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway

Wang J. et al, (2018), Scientific Reports, 8

Searching peripheral blood mononuclear cells of children with viral respiratory tract infections preceding islet autoimmunity for viruses by high-throughput sequencing

Hippich M. et al, (2018), Acta Diabetologica, 55, 881 - 884

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Burren OS. et al, (2017), Genome Biology, 18

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity

Ferreira RC. et al, (2017), Journal of Autoimmunity, 84, 75 - 86

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2

Pekalski ML. et al, (2017), JCI Insight, 2

Human IL-6R hi TIGIT − CD4 + CD127 low CD25 + T cells display potent in vitro suppressive capacity and a distinct Th17 profile

Ferreira RC. et al, (2017), Clinical Immunology, 179, 25 - 39

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