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Publications

New role of fat-free mass in cancer risk linked with genetic predisposition.

Harris BHL. et al, (2024), Scientific reports, 14

Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance.

Amarasinghe HE. et al, (2023), BMC genomics, 24

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.

Torrance HD. et al, (2023), Annals of surgery

Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis

Brown AC. et al, (2023), Cell Genomics, 3, 100306 - 100306

Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer.

Wiecek AJ. et al, (2023), Genome biology, 24

A transcriptomic approach to understand patient susceptibility to pneumonia after abdominal surgery

Torrance H. et al, (2023)

Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance

Zhang P. et al, (2022), Genome Biology, 23

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2022), Cell, 185, 916 - 938.e58

Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits

Di Giovannantonio M. et al, (2021), Journal of Medical Genetics, 58, 392 - 399

Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

Zhang P. et al, (2021), Cancer Research, 81, 1667 - 1680

Genomic hallmarks and therapeutic implications of cancer cell quiescence

Wiecek A. et al, (2021)

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Peng Y. et al, (2020), Nature Immunology, 21, 1336 - 1345

Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.

Zhao Y. et al, (2020), JCI insight, 5

Interferon-Induced Transmembrane Protein 3 Genetic Variant rs12252-C Associated With Disease Severity in Coronavirus Disease 2019

Zhang Y. et al, (2020), The Journal of Infectious Diseases, 222, 34 - 37

A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence.

Surakhy M. et al, (2020), British journal of cancer, 122, 1231 - 1241

Fam83F induces p53 stabilisation and promotes its activity.

Salama M. et al, (2019), Cell death and differentiation, 26, 2125 - 2138

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics

Pinto-Fernández A. et al, (2019), Frontiers in Chemistry, 7

iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition

Chen S. et al, (2019), Proceedings of the National Academy of Sciences, 116, 17470 - 17479

JMCB Symposium 2019: The Legend of p53 vs. Cancer

Zhang P. et al, (2019), Journal of Molecular Cell Biology, 11, 628 - 629

Polymorphisms in the p53 pathway are enriched in cancer susceptibility loci and share characteristics with somatic pathway mutations

Stracquadanio G. et al, (2016), EUROPEAN JOURNAL OF CANCER, 61, S179 - S179

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