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Publications

Low-dose IL-2 reduces IL-21+ T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes

Zhang J-Y. et al, (2022), Nature Communications, 13

Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants.

Sandholm N. et al, (2022), Scientific reports, 12

Supplementation with Bifidobacterium longum subspecies infantis EVC001 for mitigation of type 1 diabetes autoimmunity: the GPPAD-SINT1A randomised controlled trial protocol.

Ziegler A-G. et al, (2021), BMJ open, 11

Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Ferreira RC. et al, (2019), Frontiers in Immunology, 10

A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease

Peterson LB. et al, (2018), Journal of Autoimmunity, 95, 1 - 14

The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes

Seelig E. et al, (2018), JCI Insight, 3

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity

Ferreira RC. et al, (2017), Journal of Autoimmunity, 84, 75 - 86

Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells

Patel D. et al, (2017), Scientific Reports, 7

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Cutler AJ. et al, (2017), Wellcome Open Research, 2, 28 - 28

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2

Pekalski ML. et al, (2017), JCI Insight, 2

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Cutler AJ. et al, (2017), Wellcome Open Research, 2, 28 - 28

Human IL-6R hi TIGIT − CD4 + CD127 low CD25 + T cells display potent in vitro suppressive capacity and a distinct Th17 profile

Ferreira RC. et al, (2017), Clinical Immunology, 179, 25 - 39

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

Ferreira RC. et al, (2017), Data in Brief, 12, 676 - 691

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment

Ferreira RC. et al, (2017), DATA IN BRIEF, 12, 676 - 691

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial

Cutler AJ. et al, (2017), Wellcome Open Research, 2, 28 - 28

A rare IL2RA haplotype identifies SNP rs61839660 as causal for autoimmunity

Rainbow DB. et al, (2017)

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Cutler AJ. et al, (2017), Wellcome open research, 2

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

Todd JA. et al, (2016), PLOS Medicine, 13, e1002139 - e1002139

Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs

Gammage PA. et al, (2016), Nucleic Acids Research, 44, 7804 - 7816

Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

Finak G. et al, (2016), Scientific Reports, 6

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