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Publications

Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach.

Richardson TG. et al, (2022), Nature communications, 13

Identification of deleterious neutrophil states and altered granulopoiesis in sepsis

Kwok AJ. et al, (2022)

An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci.

Mountjoy E. et al, (2021), Nat Genet, 53, 1527 - 1533

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus

Downes DJ. et al, (2021), Nature Genetics, 53, 1606 - 1615

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

Robertson CC. et al, (2021), Nature genetics

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

Trzupek D. et al, (2021), Wellcome Open Research, 6, 149 - 149

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern DJ. et al, (2021)

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.

Collier DA. et al, (2021), Nature, 593, 136 - 141

SARS-CoV-2 within-host diversity and transmission

Lythgoe KA. et al, (2021), Science, 372

Analysis of overlapping genetic association in type 1 and type 2 diabetes.

Inshaw JRJ. et al, (2021), Diabetologia

In vivo negative regulation of SARS-CoV-2 receptor, ACE2, by interferons and its genetic control

Ansari MA. et al, (2021), Wellcome Open Research, 6, 47 - 47

Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.

Ghoussaini M. et al, (2021), Nucleic acids research, 49, D1311 - D1320

CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

Arroyo Hornero R. et al, (2020), Communications Biology, 3

Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

Trzupek D. et al, (2020), Genome Medicine, 12

PRF1 mutation alters immune system activation, inflammation, and risk of autoimmunity.

Sidore C. et al, (2020), Multiple sclerosis (Houndmills, Basingstoke, England)

Circulating C-peptide levels mirror patterns of residual beta cell mass in the pancreas of children and young people with type 1 diabetes

Carr ALJ. et al, (2020), DIABETOLOGIA, 63, S132 - S133

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Thaventhiran JED. et al, (2020), Nature, 583, 90 - 95

Whole-genome sequencing of patients with rare diseases in a national health system.

Turro E. et al, (2020), Nature, 583, 96 - 102

Author Correction: Approaches and advances in the genetic causes of autoimmune disease and their implications

Inshaw JRJ. et al, (2020), Nature Immunology, 21, 695 - 695

Within-host genomics of SARS-CoV-2

Lythgoe KA. et al, (2020)

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