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Publications

When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping

Sailer S. et al, (2021), Cell & Bioscience, 11

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary

Davies B. et al, (2021), Molecular Biology and Evolution

Aluminum enters mammalian cells and destabilizes chromosome structure and number

Tenan MR. et al, (2021), International Journal of Molecular Sciences, 22

Endogenous aldehyde accumulation generates genotoxicity and exhaled biomarkers in esophageal adenocarcinoma.

Antonowicz S. et al, (2021), Nat Commun, 12

Replacement of surgical vasectomy through the use of wild-type sterile hybrids

Preece C. et al, (2021), Lab Animal, 50, 49 - 52

Genomic Instability Is an Early Event in Aluminium-Induced Tumorigenesis.

Mandriota SJ. et al, (2020), International journal of molecular sciences, 21

Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma.

Tamura N. et al, (2020), Cancer research, 80, 4946 - 4959

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

Yeow ZY. et al, (2020), Nature, 585, 447 - 452

ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

Wells D. et al, (2020), eLife, 9

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

Hinch AG. et al, (2020), Molecular Cell, 79, 689 - 701.e10

Gene expressing human artificial chromosome vectors: Advantages and challenges for gene therapy.

Moralli D. and Monaco ZL., (2020), Experimental cell research

A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.

Nelson L. et al, (2020), Nature communications, 11

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

Gdula MR. et al, (2019), Nature Communications, 10

CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods.

Rayner E. et al, (2019), The CRISPR journal

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Dwivedi OP. et al, (2019), Nature Genetics, 51, 1596 - 1606

ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair

Wells D. et al, (2019)

The RS4;11 cell line as a model for leukaemia with t(4;11)(q21;q23): Revised characterisation of cytogenetic features.

Ragusa D. et al, (2019), Cancer reports (Hoboken, N.J.), 2

Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization.

Rudzka DA. et al, (2019), Journal of cell science, 132

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm

Hinch AG. et al, (2019), Science, 363, eaau8861 - eaau8861

The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α

Simões-Sousa S. et al, (2018), Cell Reports, 25, 749 - 760.e6

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