Metabolic profiling of aortic stenosis and hypertrophic cardiomyopathy identifies mechanistic contrasts in substrate utilization
Journal article
Pal N. et al, (2024), FASEB Journal, 38
Promoter Deletion Confirms That MYBPC3 Haploinsufficiency Is Sufficient to Cause Hypertrophic Cardiomyopathy in Humans
Journal article
Hayesmoore JBG. et al, (2024), Circulation: Genomic and Precision Medicine
Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy.
Journal article
Curran L. et al, (2023), Circulation. Genomic and precision medicine
Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases.
Journal article
Pagnamenta AT. et al, (2023), Genome medicine, 15
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Journal article
Lagou V. et al, (2023), Nature genetics, 55, 1448 - 1461
The penetrance of rare variants in cardiomyopathy-associated genes: A cross-sectional approach to estimating penetrance for secondary findings.
Journal article
McGurk KA. et al, (2023), American journal of human genetics, 110, 1482 - 1495
Aficamten for Drug-Refractory Severe Obstructive Hypertrophic Cardiomyopathy in Patients Receiving Disopyramide: REDWOOD-HCM Cohort 3.
Journal article
Owens AT. et al, (2023), Journal of cardiac failure
Left ventricular anatomy in obstructive hypertrophic cardiomyopathy: beyond basal septal hypertrophy
Journal article
Hermida U. et al, (2023), European Heart Journal - Cardiovascular Imaging, 24, 807 - 818
Novel insights into diminished cardiac reserve in non-obstructive hypertrophic cardiomyopathy from four-dimensional flow cardiac magnetic resonance component analysis
Journal article
Ashkir Z. et al, (2023), European Heart Journal - Cardiovascular Imaging
Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy
Journal article
Yu M. et al, (2023), Circulation: Genomic and Precision Medicine
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes.
Journal article
Robinson P. et al, (2023), Journal of molecular and cellular cardiology, 180, 44 - 57
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.
Journal article
Young WJ. et al, (2023), Nature communications, 14
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2
Journal article
Broadway-Stringer S. et al, (2023), Cells, 12, 721 - 721
Genome-Wide Analysis of Left Ventricular Maximum Wall Thickness in the UK Biobank Cohort Reveals a Shared Genetic Background With Hypertrophic Cardiomyopathy
Journal article
Aung N. et al, (2023), Circulation: Genomic and Precision Medicine, 16
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Journal article
Broadaway KA. et al, (2023), American journal of human genetics, 110, 284 - 299
Apolipoprotein Proteomics for Residual Lipid-Related Risk in Coronary Heart Disease.
Journal article
Clarke R. et al, (2023), Circ Res
Phase 2 Study of Aficamten in Patients With Obstructive Hypertrophic Cardiomyopathy.
Journal article
Maron MS. et al, (2023), Journal of the American College of Cardiology, 81, 34 - 45
Proteomic profiling identifies novel independent relationships between inflammatory proteins and myocardial infarction.
Journal article
Valdes-Marquez E. et al, (2023), European journal of preventive cardiology
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants.
Journal article
Aragam KG. et al, (2022), Nat Genet
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease
Journal article
Khera AV. et al, (2022), Circulation: Genomic and Precision Medicine