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<jats:title>Key Points</jats:title> <jats:p>Wild-type AML1 and AML1/ETO form a complex on chromatin via binding to adjacent different motifs and interacting through the runt homology domain. The relative binding signals of AML1/ETO and AML1 and AP-1 recruitment determine whether AML1/ETO activates or represses its targets.</jats:p>

Original publication

DOI

10.1182/blood-2015-03-626671

Type

Journal article

Journal

Blood

Publisher

American Society of Hematology

Publication Date

14/01/2016

Volume

127

Pages

233 - 242