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DNA polymorphisms and copy-number variants of alpha-, zeta-, and gamma-globin genes have been studied in seven Micronesian island populations and have been compared with those in populations from Southeast Asia, Melanesia, and Polynesia. Micronesians are not significantly different from Polynesians at these loci and appear to be intermediate between Southeast Asians and Melanesians. There is evidence of significant Melanesian input into the Micronesian gene pool and of substantial proto-Polynesian contact with Melanesia.

Type

Journal article

Journal

American journal of human genetics

Publication Date

01/1990

Volume

46

Pages

144 - 155

Addresses

Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, England.

Keywords

Humans, Globins, DNA, Genetics, Population, Polymorphism, Restriction Fragment Length, African Continental Ancestry Group, European Continental Ancestry Group, Pacific Islands, Micronesia