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This application claims a new method for diagnosis, prognosis and treatment of cancer using a non-invasive technique, the analysis of free circulating DNA in body fluids as a biomarker. The claimed procedure is based on the analysis of gene promoter methylation status and DNA integrity and concentration in the body fluid. Interestingly, DNA isolation from complex milieus is not required.

Original publication

DOI

10.1517/17530059.1.1.143

Type

Journal article

Journal

Expert opinion on medical diagnostics

Publication Date

09/2007

Volume

1

Pages

143 - 146

Addresses

Hospital General Universitario de Valencia Servicio de Oncología Médica and Laboratorio de Oncología Molecular, Av. Tres Cruces s/n, 46014 Valencia, Spain +34 961 972 151 ; +34 961 972 151 ; camps_car@gva.escologìa Molecular, Fundación Investigación, Hospital General Universitario, Valencia, Spain.