Professor Pier Francesco Palamara
Contact information
Research groups
Professor Pier Francesco Palamara
Associate Professor of Statistical and Population Genetics
My research is at the intersection of statistics, computer science, and genetics. Our group develops statistical and machine learning algorithms to enable new types of analyses in large human genomic data sets. Specific areas of research include developing algorithms for simulation, reconstruction, and analysis of large-scale genealogical data (gene genealogies, haplotype sharing, phasing, imputation); studying demographic events and evolutionary parameters (migration, expansion/contraction of populations, natural selection, mutation/recombination rates); studying the genetic architecture of complex traits and detecting disease-causing variation in the human genome (heritability, polygenic prediction, association).
Additional details can be found at https://www.stats.ox.ac.uk/~palamara.
Recent publications
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Genome-wide classification of epigenetic activity reveals regions of enriched heritability in immune-related traits.
Journal article
Stricker M. et al, (2024), Cell genomics, 4
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Genome-wide classification of epigenetic activity reveals regions of enriched heritability in immune-related traits.
Journal article
Stricker M. et al, (2023), Cell genomics
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Haplotype-based inference of recent effective population size in modern and ancient DNA samples.
Journal article
Fournier R. et al, (2023), Nature communications, 14
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HAPNEST: efficient, large-scale generation and evaluation of synthetic datasets for genotypes and phenotypes.
Journal article
Wharrie S. et al, (2023), Bioinformatics (Oxford, England), 39
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Inference of coalescence times and variant ages using convolutional neural networks.
Journal article
Nait Saada J. et al, (2023), Molecular biology and evolution