Contact information
Cathy Oliveira
Postdoctoral Research Associate and Lab Manager
Short Biography: I obtained my B.Sc. from Worcester Polytechnic Institute in Worcester, Massachusetts, and worked for a number of cell and gene therapy biotech companies in the US, Singapore, and the UK. I began working for Oxford University in 2008 as a Production Manager at the Clinical Biomanufacturing Facility, overseeing the manufacture of adenovirus-based vaccines against malaria and HIV. I started my D.Phil. studies in 2011 under the supervision of Prof. Deborah Gill and Prof. Steve Hyde in the Gene Medicine Research Group, where I investigated enhancer and promoter function in non-viral vectors used in clinical gene therapy studies for treatment of lung diseases, such as Cystic Fibrosis. I joined the Genome Integrity group in April 2015.
Research Interests: B-cell development, class-switch recombination, V(D)J recombination, transgenic models
Key publications
-
Journal article
Ghezraoui H. et al, (2018), Nature, 560, 122 - 127
Recent publications
-
An essential role for the Zn2+ transporter ZIP7 in B cell development
Journal article
Anzilotti C. et al, (2019), Nature Immunology, 20, 350 - 361
-
The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
Journal article
Becker JR. et al, (2018), Nature Communications, 9
-
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
Journal article
Ghezraoui H. et al, (2018), Nature, 560, 122 - 127
-
Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein
Journal article
Botuyan MV. et al, (2018), Nature Structural & Molecular Biology, 25, 591 - 600
-
Abstract PR20: A 53BP1 integrates DNA repair and p53-dependent cell fate decisions via distinct mechanisms
Conference paper
Cuella-Martin R. et al, (2017), DNA Damage Signaling