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Márton Münz

Postdoctoral research associate


Research summary

My research interests are centered around the application of high-throughput sequencing technology as a powerful tool to address complex biological questions such as understanding disease susceptibility and progression. I work in two major projects:

1. I am involved in the development of a targeted next-generation sequencing (NGS) data analysis pipeline in the Mainstreaming Cancer Genetics (MCG) programme (in collaboration with the Institute of Cancer Research and The Royal Marsden Hospital, London). The MCG programme is using NGS to increase the availability and affordability of clinical testing of cancer predisposition genes (CPGs) (see http://mcgprogramme.com). The main focus of my work is quality control, small variant calling and variant annotation of NGS data for which I develop software tools.

2. I work on the analysis of Rep-Seq (repertoire sequencing) data to study the responses of the adaptive immune system to vaccination (in collaboration with the Oxford Vaccine Group, Churchill Hospital). The main goal of this project is to accurately predict vaccination efficiency using an NGS-based approach.