George Busby
Contact information
George Busby
Post-doctoral research associate
Research overview
George works in Chris Spencer's group in Oxford as a collaboration with MalariaGEN on the analysis of human genetic data. He explores the effects of demography and natural selection on the human genome. He is currently working with a large African dataset developing new models to identify regions of the genome that may have been altered in response to infectious disease. He is also interested in using genetic data to uncover novel inferences about our evolutionary past, and has helped developed models that characterise recent human admixture history.
Selected publications
Montinaro F, Busby, GBJ, Pascali VL, Myers S, Hellenthal G, Capelli C Unravelling the hidden ancestry of american admixed populations. (in press) Nature Communications.
Hellenthal G, Busby, GBJ, Band G, Wilson JF, Capelli C, Falush D, Myers S (2014) A genetic atlas of human admixture history. Science 343: 747–751
Busby, GBJ, Brisighelli F, Sánchez-Diz P, Ramos-Luis E, Martinez-Cadenas C, Thomas MG, Bradley DG, GusmãoL, Winney B, Bodmer W, Vennemann M, Coia V, Scarnicci F, Tofanelli S, Vona G, Ploski R, Vecchiotti C, Zemunik T, Rudan I, Karachanak S, Toncheva D, Anagnostou P, Ferri G, Rapone C, Hervig T, Moen T, Wilson JF, Capelli C (2012) The peopling of Europe and the cautionary tale of y chromosome lineage r-m269. Proceedings of the Royal Society B: Biological Sciences 279: 884 –892.
Recent publications
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Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Journal article
Ndila CM. et al, (2018), The Lancet Haematology, 5, e333 - e345
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Inferring adaptive gene-flow in recent African history
Journal article
Busby G. et al, (2017)
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Resistance to malaria through structural variation of red blood cell invasion receptors
Journal article
Leffler EM. et al, (2017), Science, 356, eaam6393 - eaam6393
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Complex Ancient Genetic Structure and Cultural Transitions in Southern African Populations
Journal article
Montinaro F. et al, (2017), Genetics, 205, 303 - 316
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Resistance to malaria through structural variation of red blood cell invasion receptors
Working paper
Leffler E. et al, (2016)