DPhil Student in Genomic Medicine and Statistics
I am a DPhil student investigating patterns of gene expression in meiosis. This process is a type of cell division which is critical to the evolution, fertility, and speciation of sexually reproducing organisms. Resolving the full gene expression profile of meiosis should help to identify the genes involved in meiosis and thence the mechanisms and regulatory processes.
Previously I completed an integrated masters degree in biochemistry at the University of Oxford and two computational rotation projects as part of my first year in the genomic medicine and statistics DPhil programme.
ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair
Wells D. et al, (2019)
Unified single-cell analysis of testis gene regulation and pathology in five mouse strains
Jung M. et al, (2019), eLife, 8
Genome and epigenome engineering CRISPR toolkit forin vivomodulation ofcis-regulatory interactions and gene expression in the chicken embryo
Williams RM. et al, (2018), Development, 145, dev160333 - dev160333
Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model
Munster VJ. et al, (2017), npj Vaccines, 2
Case Commentary: Severe Combined Immune Deficiencies
Wells D., (2017)