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Research groups

Antony Cutler

Senior Research Associate

My research takes an integrative approach to translate genetic association and functional genomic data to identify causal genes that underlie susceptibility to type 1 diabetes. We use a variety of functional genomic approaches to annotate regulatory landscape of chromatin in T and B cells in different activation states to identify causal single nucleotide variants and the genes that they control.  We then translate these findings using the Oxford BioBank, a genotype selectable human resource of healthy individuals, to investigate the effect of disease-associated variants in relation to gene and protein expression.

I obtained my PhD at the University of Manchester studying the mechanisms of tolerance induction in transplantation using cell-based approaches. I have subsequently worked in the field of immune tolerance in autoimmunity and transplantation through my career.