The Oxford Genomics Centre as part of the Wellcome Trust Centre for Human Genetics is a partner in the Oxford Consortium for Single-Cell Biology (Oxford ConSiCe Biology), receiving a share in a £4.9M award from the MRC’s Clinical Research Capabilities and Technologies Initiative which will be used to develop single-cell capabilities
(see news item: Developing Single-Cell Capability).
We offer a wide and growing range of genomics applications for single cells, including RNA-seq, gene expression profiling, immune clonotype profiling, cell surface proteins, antigen specifity, chromatin accessibility, and DNA amplification for whole-genome or targeted (exome or PCR-based) analysis. Applications are supported by 10X Genomics Chromium platform, or in conventional multi-well plates using FACS (cell sorting) combined with low-volume, automated liquid handling.
The 10X Genomics Chromium™ Controller is a platform designed to deliver highly parallel sample partitioning and molecular barcoding. It supports a variety of applications, including the well-established 10X Genomics Linked-Read technology for genome analysis and the existing Chromium™ Single Cell 3’ Solution for single cell transcriptomics, allowing cell characterization and gene expression profiling of hundreds to millions of cells.
For more information please visit: www.10xgenomics.com.
To discuss your project requirements please contact us.
SH800Z cell sorter features a novel microfluidics sorting chip integrated with comprehensive fluidics controls to simplify system and sort setup.
A flexible optical design offers up to 4 collinear excitation lasers (488 nm, 405nm, 561nm and 638nm) and 6 fluorescence detectors. The six free-form PMTs enable detection of fluorescence signals from any laser based on filter selection.
OGC offers a complete workflow from cell suspension to sequencing-ready library (SmartSeq2 combined with NexteraXT)
Please contact us if you’re interested in using our cell sorting facility.
Before you begin
It can take some time to decide on your preferred experimental design through discussions with our team. Once this is finalised, you should request a quote from our project management team at least 2 weeks before you wish to go ahead with a run.
In order to proceed with your run, a submission form must be received by your project manager 48 working hours in advance. If the submission form is not received, the run WILL BE CANCELLED.
Our sample guidelines contain more information about the steps required in advance of a run and sample requirements.