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Red blood cell variation linked to natural malaria resistance

Protection from the most severe form of malaria is linked with natural variation in human red blood cell genes. Led by Professor Dominic Kwiatkowski, researchers from the Wellcome Trust Centre for Human Genetics and the Wellcome Trust Sanger Institute have identified a genetic rearrangement of red blood cell glycophorin receptors that confers a 40% reduced risk from severe malaria.

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