Papers |
Bice P, Valdar W, Zhang L, Liu L, Lai D, Grahame N, Flint J, Li TK, Lumeng L, Foroud T (2008) Genomewide SNP Screen to Detect Quantitative Trait Loci for Alcohol Preference in the High Alcohol Preferring and Low Alcohol Preferring Mice. Alcohol Clin Exp Res. Dec 19. [Epub ahead of print]
Wallis-Owen SAG, Valdar W (2008) Deciphering gene-environment interactions through mouse models of allergic asthma. Journal of Allergy and Clinical Immunology J Allergy Clin Immunol. 123(1):14-23.
Ramagopalan SV, Herrera BM, Valdar W, Dyment DA, Orton SM, Yee IM,
Criscuoli M, Atkins K, Ebers GC, Sadovnick AD (2008) No Effect of Birth
Weight on the Risk of Multiple Sclerosis. A Population-Based Study.
Neuroepidemiology 31(3):181-184
Ramagopalan SV, Valdar W, Dyment DA, DeLuca GC, Orton SM, Yee IM,
Criscuoli M, Ebers GC, Sadovnick AD; Canadian Collaborative Study Group
(2008) No effect of preterm birth on the risk of multiple sclerosis: a
population based study. BMC Neurol 8:30
Lopez-Aumatell R, Guitart-Masip M, Vicens-Costa E, Gimenez-Llort L,
Valdar W, Johannesson M, Flint J, Tobeña A, Fernandez-Teruel A
(2008) Fearfulness in a large N/Nih genetically heterogeneous rat
stock: differential profiles of timidity and defensive flight in males
and females. Behav Brain Res. 188(1):41-55. Epub 2007 Oct 26.
Ramagopalan SV, Dyment DA, Valdar W, Herrera BM,
Criscuoli M, Yee IM, Sadovnick AD, Ebers GC;
Canadian Collaborative Study Group (2007)
Lancet Neurol. 6(7):604-10 PubMed
Valdar W, Mott R, Flint J
(2006)
Simulating the collaborative cross: power of QTL detection and mapping
resolution
in large sets of recombinant inbred strains of mice. Genetics 172(3):1783-97 PubMed
PDF
Flint J, Valdar W,
Shifman S, Mott R (2005) Experimental strategies for mapping and
cloning quantitative
trait genes in rodents. Nature Reviews Genetics 6, 271-286
PubMed
Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J,
Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M,
Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM,
Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A,
Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ,
Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL,
Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA,
Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE,
Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F,
Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R,
Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS,
Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H,
Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K,
Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M,
Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC,
Seltzer Z, Shimomura K, Shou S, Sillanpaa MJ, Siracusa LD, Snoeck HW,
Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP,
Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M,
Zou F; Complex Trait Consortium (2004) The Collaborative Cross, a
community resource for the
genetic
analysis of complex traits. Nature Genetics 36(11):1133-7 PubMed
Valdar WSJ, Mott R,
Flint
J (2003) QTL fine-mapping with recombinant-inbred heterogeneous stocks
and
in-vitro heterogeneous stocks. Mammalian
Genome.14(12):830-838 PubMed
PDF
Valdar WSJ (2002) Scoring residue conservation. Proteins: Structure, Function, and Genetics 43(2): 227-241. PubMed PDF Errata
Nobeli I, Laskowski RA, Valdar WSJ, Thornton JM (2001) On the molecular discrimination between adenine and guanine in proteins. Nucleic Acids Research 29(21): 4294-4309 PubMed PDF
Valdar WSJ, Thornton JM (2001) Conservation helps to identify biologically relevant crystal contacts. Journal of Molecular Biology 313(2): 399-416. PubMed PDF Errata
Valdar WSJ,
Thornton
JM (2001) Protein-protein interfaces: analysis of amino acid
conservation
in homodimers. Proteins: Structure, Function, and Genetics
42(1):
108-124.
PubMed PDF
Books & Chapters |
Posters |
Valdar WSJ, Thornton JM (2000) Residue conservation at protein-protein interfaces. Bloomsbury Centre for Structural Biology Annual Meeting. Slideshow
Valdar WSJ, Thornton JM (1999) Residue conservation at
protein-protein
interfaces. ISMB99, Heidelberg, Germany. Abstract
Talks |
"Mapping quantitative trait loci in heterogeneous stock mice". Center for Human Genetic Research, Mass General Hospital, Harvard University, USA (September 2005)
"Mapping genes that affect common diseases using outbred animals"
MRC Laboratory
of Molecular Biology, Cambridge University, UK(July 2005) abstract
"Mapping quantitative trait loci in heterogeneous stock mice"
Complex Trait
Consortium 2005, 4th Annual Conference. University of Groningen, The
Netherlands
(June 2005)
"Simulating the collaborative cross: power of QTL detection and
mapping resolution in large sets of recombinant inbred strains of
mice". The Linnaeus Centre for Bioinformatics, Uppsala University,
Sweden (February 2005) PDF
"Collaborative Cross RILs and related strategies for fine-mapping
small
effect QTLs". Complex Trait Consortium 2004, 3rd Annual
Conference.
Jackson Laboratory, Bar Harbour, Maine USA (July 2004) PDF
"Mapping epistasis in RIHS or Exstatic: an epistatic extension to
HAPPY".
BioStag meeting, WTCHG, Oxford University, UK (November 2003)
"Fine mapping QTLs using recombinant inbred HS and in vitro HS". Complex Trait Consortium 2003, 2nd Annual Conference, Oxford University, UK (July 2003) PDF
"Residue conservation at protein-protein interfaces". Talk on my PhD to the Gerstein group at Yale University, USA (March 2001). Slideshow
"Conservation at protein-protein interfaces". Final year PhD talk to
UCL
Biochemistry department, UK (May 2000). Slideshow
Theses |
Valdar WSJ (2003) Detection of epistatic quantitative trait loci in murine heterogeneous stock recombinant inbred lines. MSc thesis (subject: applied statistics), Oxford University.
Valdar WSJ (2001) Residue conservation in the prediction of protein-protein interfaces. PhD thesis (subject: protein structure bioinformatics), University College London. PDF
Valdar WSJ (1998) J-Features: development of a java-based feature table editor. MSc thesis (subject: bioinformatics), Manchester University. PDF