1985 1986 198719881989
19901991 199219931994
199519961997
199819992000
Publications
Scambler PJ, Wainwright BJ, Farrall M, Bell J, Stanier P, Lench NJ, Bell G, Kruyer H, Ramirez F, Williamson R. Linkage of COL1A2 collagen gene to cystic fibrosis, and its clinical implications [letter] Lancet. 1985 Nov 30; 2(8466): 1241-2
Wainwright BJ, Scambler PJ, Schmidtke J, Watson EA, Law HY, Farrall M, Cooke HJ, Eiberg H, Williamson R. Localization of cystic fibrosis locus to human chromosome 7cen-q22. Nature. 1985 Nov 28-Dec 4; 318(6044): 384-5
Beaudet A, Bowcock A, Buchwald M, Cavalli Sforza L, Farrall M, King MC, Klinger K, Lalouel JM, Lathrop G, Naylor S, et al. Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study. Am J Hum Genet. 1986 Dec; 39(6): 681-93
Farrall M, Law HY, Rodeck CH, Warren R, Stanier P, Super M, Lissens W, Scambler P, Watson E, Wainwright B, et al. First-trimester prenatal diagnosis of cystic fibrosis with linked DNA probes. Lancet. 1986 Jun 21; 1(8495): 1402-5
Farrall M, Scambler P, Klinger KW, Davies K, Worrall C, Williamson R, Wainwright B. Cystic fibrosis carrier detection using a linked gene probe. J Med Genet. 1986 Aug; 23(4): 295-9
Farrall M, Scambler P, North P, Williamson R. The analysis of multiple polymorphic loci on a single human chromosome to exclude linkage to inherited disease: cystic fibrosis and chromosome 4. Am J Hum Genet. 1986 Jan; 38(1): 75-83
Farrall M, Watson E, Bates G, Bell G, Bell J, Davies KA, Estivill X, Kruyer H, Law HY, Lench N, et al. Further data supporting linkage between cystic fibrosis and the met oncogene and haplotype analysis with met and pJ3.11. Am J Hum Genet. 1986 Dec; 39(6): 713-9
Klinger K, Stanislovitis P, Hoffman N, Watkins PC, Schwartz R, Doherty R, Scambler P, Farrall M, Williamson R, Wainwright B. Genetic homogeneity of cystic fibrosis. Nucleic Acids Res. 1986 Nov 11; 14(21): 8681-6
Scambler PJ, Bell G, Watson E, Farrall M, Bates G, Davies K, Lench N, Ashworth A, Williamson R, Tippett P, et al. Cystic fibrosis linkage exclusion data. Cytogenet Cell Genet. 1986; 41(1): 62-3
Scambler PJ, Wainwright BJ, Watson E, Bates G, Bell G, Williamson R, Farrall M. Isolation of a further anonymous informative DNA sequence from chromosome seven closely linked to cystic fibrosis. Nucleic Acids Res. 1986 Mar 11; 14(5): 1951-6
Wainwright B, Farrall M, Watson E, Williamson R. A model system for the analysis of gene exclusion: cystic fibrosis and chromosome 19. J Med Genet. 1986 Oct; 23(5): 417-20
Wainwright B, Scambler P, Farrall M, Schwartz M, Williamson R. Linkage between the cystic fibrosis locus and markers on chromosome 7q. Cytogenet Cell Genet. 1986; 41(3): 191-2
Williamson R, Bell G, Bell J, Bates G, Davies KA, Estivill X, Farrall M, Kruyer H, Law HY, Lench N, et al. Molecular genetics and the basic defect causing cystic fibrosis. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 1: 309-15
Berger W, Hein J, Gedschold J, Bauer I, Speer A, Farrall M, Williamson R, Coutelle C. Crossovers in two German cystic fibrosis families determine probe order for MET, 7C22 and XV-2c/CS.7. Hum Genet. 1987 Oct; 77(2): 197-9
Chamberlain S, Worrall CS, South S, Shaw J, Farrall M, Williamson R. Exclusion of the Friedreich ataxia gene from chromosome 19. Hum Genet. 1987 Jun; 76(2): 186-90
Davies KA, Lorand L, Waterfield M, Wainwright B, Farrall M, Williamson R. Isolation of a polymorphic genomic clone from chromosome 7. Physical and genetic linkage studies to markers around the cystic fibrosis locus. Hum Genet. 1987 Oct; 77(2): 122-6
Estivill X, Bates G, Bell G, Farrall M, Frederick P, Hawley K, Kruyer H, Lench N, Scrambler P, Stanier P, et al. The application of molecular genetics to the study of the basic defect causing cystic fibrosis. Prog Clin Biol Res. 1987; 254: 181-90
Estivill X, Farrall M, Scambler PJ, Bell GM, Hawley KM, Lench NJ, Bates GP, Kruyer HC, Frederick PA, Stanier P, et al. A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands. Nature. 1987 Apr 30-May 6; 326(6116): 840-5
Estivill X, Scambler PJ, Wainwright BJ, Hawley K, Frederick P, Schwartz M, Baiget M, Kere J, Williamson R, Farrall M. Patterns of polymorphism and linkage disequilibrium for cystic fibrosis. Genomics. 1987 Nov; 1(3): 257-63
Farrall M, Estivill X, Williamson R. Indirect cystic fibrosis carrier detection [letter] Lancet. 1987 Jul 18; 2(8551): 156-7
Farrall M, Lathrop M, Spence JE, Bowcock A, Klinger K, Tsui LC. Further data on linkage between cystic fibrosis and 7C22 (D7S16) [letter] Am J Hum Genet. 1987 Aug; 41(2): 286-7
O'Connell P, Leppert M, Nakamura Y, Dean M, Park M, Vande Woude G, Farrall M, Wainwright B, Williamson R, Lathrop GM, et al. DNA markers for the cystic fibrosis locus. Prog Clin -Biol Res. 1987; 254: 127-37
Law HY, Stanier P, Williamson R, Modell B, Ward RH, Petrou M, Old J, Farrall M. Two unusual cases of first trimester prenatal diagnosis of cystic fibrosis using DNA probes. Prenat Diagn. 1987 Mar; 7(3): 215-21
Moore GE, Ivens A, Chambers J, Farrall M, Williamson R, Page DC, Bjornsson A, Arnason A, Jensson O. Linkage of an X-chromosome cleft palate gene. Nature. 1987 Mar 5-11; 326(6108): 91-2
Scambler PJ, Estivill X, Bell G, Farrall M, McLean C, Newman R, Little PF, Frederick P, Hawley K, Wainwright BJ, et al. Physical and genetic analysis of cosmids from the vicinity of the cystic fibrosis locus. Nucleic Acids Res. 1987 May 11; 15(9): 3639-52
Scambler P, Oyen O, Wainwright B, Farrall M, Law HY, Estivill X, Sandberg M, Williamson R, Jahnsen T. Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis. Am J Hum Genet. 1987 Nov; 41(5): 925-32
Wainwright B, Lench N, Davies K, Scambler P, Kruyer H, Williamson R, Jahnsen T, Farrall M. A human regulatory subunit of type II cAMP-dependent protein kinase localized by its linkage relationship to several cloned chromosome 7q markers. Cytogenet Cell Genet. 1987; 45(3-4): 237-9
Williamson R, Wainwright B, Cooper C, Scambler P, Farrall M, Estivill X, Pedersen P. The cystic fibrosis locus. Enzyme. 1987; 38(1-4): 8-13
Beaudet AL, Spence JE, Montes M, O'Brien WE, Estivill X, Farrall M, Williamson R. Experience with new DNA markers for the diagnosis of cystic fibrosis [letter] N Engl J Med. 1988 Jan 7; 318(1): 50-1
Brooks BA, McBride OW, Dolphin CT, Farrall M, Scambler PJ, Gonzalez FJ, Idle JR. The gene CYP3 encoding P450pcn1 (nifedipine oxidase) is tightly linked to the gene COL1A2 encoding collagen type 1 alpha on 7q21-q22.1. Am J Hum Genet. 1988 Sep; 43(3): 280-4
Chamberlain S, Shaw J, Rowland A, Wallis J, South S, Nakamura Y, von Gabain A, Farrall M, Williamson R. Mapping of mutation causing Friedreich's ataxia to human chromosome 9. Nature. 1988 Jul 21; 334(6179): 248-50
Estivill X, Farrall M, Williamson R, Ferrari M, Seia M, Giunta AM, Novelli G, Potenza L, Dallapicolla B, Borgo G, et al. Linkage disequilibrium between cystic fibrosis and linked DNA polymorphisms in Italian families: a collaborative study. Am J Hum Genet. 1988 Jul; 43(1): 23-8
Farrall M, Wainwright BJ, Feldman GL, Beaudet A, Sretenovic Z, Halley D, Simon M, Dickerman L, Devoto M, Romeo G, et al. Recombinations between IRP and cystic fibrosis. Am J Hum Genet. 1988 Oct; 43(4): 471-5
Lathrop GM, Farrall M, O'Connell P, Wainwright B, Leppert M, Nakamura Y, Lench N, Kruyer H, Dean M, Park M, et al. Refined linkage map of chromosome 7 in the region of the cystic fibrosis gene. Am J Hum Genet. 1988 Jan; 42(1): 38-44
Mornet E, Simon Bouy B, Serre JL, Estivill X, Farrall M, Williamson R, Boue J, Boue A. Genetic differences between cystic fibrosis with and without meconium ileus. Lancet. 1988 Feb 20; 1(8582): 376-8
Schwartz M, Super M, Schmidtke J, Buys C, Farrall M, Halley D, Krawczak M, Poncin JE, Loukopoulos D, Devoto M. Prenatal diagnosis of cystic fibrosis using linked DNA probes. Prenat Diagn. 1988 Oct; 8(8): 619-24
Tsui LC, Farrall M, Donis Keller H. Report of the committee on the genetic constitution of chromosomes 7 and 8. Cytogenet Cell Genet. 1988; 49(1-3): 60-70
Wainwright BJ, Scambler PJ, Stanier P, Watson EK, Bell G, Wicking C, Estivill X, Courtney M, Boue A, Pedersen PS, Williamson R, Farrall M Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless. EMBO J 1988 7:1743-1748.
Chamberlain S, Shaw J, Wallis J, Rowland A, Chow L, Farrall M, Keats B, Richter A, Roy M, Melancon S, et al. Genetic homogeneity at the Friedreich ataxia locus on chromosome 9. Am J Hum Genet. 1989 Apr; 44(4): 518-21
Farrall M, Scambler PJ. Cystic fibrosis [scientific correspondence] Nature. 1989 Mar 2; 338(6210): 24
Goate AM, Haynes AR, Owen MJ, Farrall M, James LA, Lai LY, Mullan MJ, Roques P, Rossor MN, Williamson R, et al. Predisposing locus for Alzheimer's disease on chromosome 21. Lancet. 1989 Feb 18; 1(8634): 352-5
Lathrop GM, O'Connell P, Leppert M, Nakamura Y, Farrall M, Tsui LC, Lalouel JM, White R. Twenty-five loci form a continuous linkage map of markers for human chromosome 7. Genomics. 1989 Nov; 5(4): 866-73
Tsui LC, Farrall M, Donis Keller H. Report of the committee on the genetic constitution of chromosomes 7 and 8. Cytogenet Cell Genet. 1989; 51(1-4): 166-201
Wallis J, Shaw J, Wilkes D, Farrall M, Williamson R, Chamberlain S, Skare JC, Milunsky A. Prenatal diagnosis of Friedreich ataxia. Am J Med Genet. 1989 Nov; 34(3): 458-61
Auburger G, Diaz GO, Capote RF, Sanchez SG, Perez MP, del Cueto ME, Meneses MG, Farrall M, Williamson R, Chamberlain S, et al. Autosomal dominant ataxia: genetic evidence for locus heterogeneity from a Cuban founder-effect population. Am J Hum Genet. 1990 Jun; 46(6): 1163-77
Goate AM, Hardy JA, Owen MJ, Haynes A, James L, Farrall M, Mullan MJ, Roques P, Rossor MN. Genetics of Alzheimer's disease. Adv Neurol. 1990; 51: 197-8
Healy JM, Lehane M, Heffron JJ, Farrall M, Johnson K, McCarthy TV. Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-q13.2. Biochem Soc Trans. 1990; 18(2): 326
McCarthy TV, Healy JM, Heffron JJ, Lehane M, Deufel T, Lehmann Horn F, Farrall M, Johnson K. Localization of the malignant hyperthermia susceptibility locus to human chromosome 19q12-13.2. Nature. 1990 Feb 8; 343(6258): 562-4
McConville CM, Woods CG, Farrall M, Metcalfe JA, Taylor AM. Analysis of 7 polymorphic markers at chromosome 11q22-23 in 35 ataxia telangiectasia families; further evidence of linkage. Hum Genet. 1990 Jul; 85(2): 215-20
Scambler PJ, Wainwright B, Ramsay M, Farrall M, Bates G, Ho MF, Cooper C. Analysis of the transgenome of MET transfectant cell lines reveals that MET activation is accompanied by an interstitial insertion. Hum Genet. 1990 Feb; 84(3): 274-8
Ramsay M, Wainwright BJ, Farrall M, Estivill X, Sutherland H, Ho MF, Davies R, Halford S, Tata F, Wicking C, et al. A new polymorphic locus, D7S411, isolated by cloning from preparative pulse-field gels is close to the mutation causing cystic fibrosis. Genomics. 1990 Jan; 6(1): 39-47
Tsui LC, Farrall M. Report of the committee on the genetic constitution of chromosome 7. Cytogenet Cell Genet. 1990; 55(1-4): 122-7
Dixon MJ, Haan E, Baker E, David D, McKenzie N, Williamson R, Mulley J, Farrall M, Callen D. Association of Treacher Collins syndrome and translocation 6p21.31/16p13.11: exclusion of the locus from these candidate regions. Am J Hum Genet. 1991 Feb; 48(2): 274-80
Farrall M Mapping inherited diseases by linkage analysis. In "Methods in Molecular Biology, Vol. 9: Protocols in Human Molecular Genetics". Edited by CG Mathew, The Humana Press Inc., Clifton, NJ, USA 1991
Wojciechowski AP, Farrall M, Cullen P, Wilson TM, Bayliss JD, Farren B, Griffin BA, Caslake MJ, Packard CJ, Shepherd J, et al. Familial combined hyperlipidaemia linked to the apolipoprotein AI-CII-AIV gene cluster on chromosome 11q23-q24. Nature. 1991 Jan 10; 349(6305): 161-4
al-Imara L, Richards AJ, Eady RA, Leigh IM, Farrall M, Pope FM. Linkage of autosomal dominant dystrophic epidermolysis bullosa in three British families to the marker D3S2 close to the COL7A1 locus. J Med Genet. 1992 Jun; 29(6): 381-2
Farrall M, Holder S. Familial recurrence-pattern analysis of cleft lip with or without cleft palate. Am J Hum Genet. 1992 Feb; 50(2): 270-7
Dorin JR, Emslie E, Hanratty D, Farrall M, Gosden J, Porteous DJ. Gene targeting for somatic cell manipulation: rapid analysis of reduced chromosome hybrids by Alu-PCR fingerprinting and chromosome painting. Hum Mol Genet. 1992 Apr; 1(1): 53-9
Ramsay M, Colman MA, Stevens G, Zwane E, Kromberg J, Farrall M, Jenkins T. The tyrosinase-positive oculocutaneous albinism locus maps to chromosome 15q11.2-q12. Am J Hum Genet. 1992 Oct; 51(4): 879-84
Chamberlain S, Farrall M, Shaw J, Wilkes D, Carvajal J, Hillerman R, Doudney K, Harding AE, Williamson R, Sirugo G, et al. Genetic recombination events which position the Friedreich ataxia locus proximal to the D9S15/D9S5 linkage group on chromosome 9q. Am J Hum Genet. 1993 Jan; 52(1): 99-109
Farrall M. Inheritance of chronic inflammatory bowel disease [letter] BMJ. 1993 Mar 6; 306(6878): 651
Farrall M. Homozygosity mapping: familiarity breeds debility [news and views] Nature Genetics. 1993 Oct; 5(2): 107-8
FitzPatrick D, Farrall M. An estimation of the number of susceptibility loci for isolated cleft palate. J Craniofac Genet Dev Biol. 1993 Oct-Dec; 13(4): 230-5
Farrall M, Buetow KH, Murray JC. Resolving an apparent paradox concerning the role of TGFA in CL/P [letter] Am J Hum Genet. 1993 Feb; 52(2): 434-7
Gispert S, Twells R, Orozco G, Brice A, Weber J, Heredero L, Scheufler K, Riler B, Allotey R, Nothers C, Hillermann R, Lunkes A, Khati C, Stevanin G, Hernandez A, Magarino C, Klockgether T, Durr A, Chneiweiss H, Enczmann J, Farrall M, Beckmann J, Mullan M, Wernet P, Agid Y, Freund H-J, Williamson R, Augueger G, Chamberlain S Chromosomal assignment of the second locus for autosomal dominant cerebellar ataxia (SCA2) to chromosome 12q23-24.1. Nature Genetics 1993 4:295-299
Caulfield M, Lavender P, Farrall M, Munroe P, Lawson M, Turner P, Clark AJ. Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med. 1994 Jun 9; 330(23): 1629-33
Cullen P, Farren B, Scott J, Farrall M. Complex segregation analysis provides evidence for a major gene acting on serum triglyceride levels in 55 British families with familial combined hyperlipidemia. Arterioscler Thromb. 1994 Aug; 14(8): 1233-49
Dunnill MG, Richards AJ, Milana G, Mollica F, Atherton D, Winship I, Farrall M, al-Imara L, Eady RA, Pope FM. Genetic linkage to the type VII collagen gene (COL7A1) in 26 families with generalised recessive dystrophic epidermolysis bullosa and anchoring fibril abnormalities. J Med Genet. 1994 Oct; 31(10): 745-8
Davies JL, Kawaguchi Y, Bennett ST, Copeman JB, Cordell HJ, Pritchard LE, Reed PW, Gough SC, Jenkins SC, Palmer SM, Balfour KM, Rowe BR, Farrall M, Barnett AH, Bain SC, Todd JA. A genome-wide search for human type 1 diabetes susceptibility genes. Nature. 1994 371:130-6.
Newton R, Stanier P, Loughna S, Henderson DJ, Forbes SA, Farrall M, Jensson O, Moore GE. Linkage analysis of 62 X-chromosomal loci excludes the X chromosome in an Icelandic family showing apparent X-linked recessive inheritance of neural tube defects. Clin Genet. 1994 May; 45(5): 241-9
Twells R, Yenchitsomanus PT, Sirinavin C, Allotey R, Poungvarin N, Viriyavejakul A, Cemal C, Weber J, Farrall M, Rodprasert P, et al. Autosomal dominant cerebellar ataxia with dementia: evidence for a fourth disease locus. Hum Mol Genet. 1994 Jan; 3(1): 177-80
Caulfield M, Lavender P, Newell Price J, Farrall M, Kamdar S, Daniel H, Lawson M, De Freitas P, Fogarty P, Clark AJ. Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. J Clin Invest. 1995 Aug; 96(2): 687-92
Cordell HJ, Kawaguchi Y, Todd JA, Farrall M. An extension of the maximum lod score method to X-linked loci. Ann Hum Genet. 1995 Oct; 59 ( Pt 4): 435-49
Cordell HJ, Todd JA, Bennett ST, Kawaguchi Y, Farrall M. Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes. Am J Hum Genet. 1995 Oct; 57(4): 920-34
McKenzie CA, Julier C, Forrester T, McFarlane Anderson N, Keavney B, Lathrop GM, Ratcliffe PJ, Farrall M. Segregation and linkage analysis of serum angiotensin I-converting enzyme levels: evidence for two quantitative-trait loci. Am J Hum Genet. 1995 Dec; 57(6): 1426-35
Munroe PB, Daniel HI, Farrall M, Lawson M, Bouloux PM, Caulfield MJ. Absence of genetic linkage between polymorphisms of the insulin receptor gene and essential hypertension. J Hum Hypertens. 1995 Aug; 9(8): 669-70
The Cystinosis Collaborative Research group. Linkage of the gene for cystinosis to markers on the short arm of chromosome 17. Nature Genetics 1995 10:246-248
Caulfield M, Lavender P, Newell-Price J, Kamdar S, Farrall M, Clark AJ Angiotensinogen in human essential hypertension., Hypertension 1996 28:1123-5
Farrall M. Mapping genetic susceptibility to multiple sclerosis. [invited commentary] Lancet 1996 348:1674-75
Todd J, Farrall M Panning for gold: genome-wide scanning for linkage in type 1 diabetes. [review] Hum Mol Genet 1996 5:1443-8
Bonyadi M, Rushholme SAB, Cousins F, Farrall M, Akhurst RJ. Mapping of a major modifier of embryonic lethality in TGFß1 knockout mice. Nature Genetics 1997 15:207-212
Farrall M. LODWars: The Affected-Sibling-Pair paradigm strikes back! [letter] Am J Hum Genet. 1997 60:735-738
Farrall M. Affected sibpair linkage tests for multiple linked susceptibility genes. Genet Epidemiol 1997 14:103-115
Hughes DC, Allen J, Morley G, Sutherland K, Ahmed W, Prosser J, Lettice L, Allen G, Mattei M-G, Farrall M, Hill RE. Cloning and sequencing of the mouse gli2 gene:Localisation to the Dominant Hemimelia critical region. Genomics 1997 39:205-215
Rubio JP, Danek A, Stone C, Chalmers R, Wood N, Verellen C, Ferrer X, Malandrini A, Fabrizi GM, Manfredi M, Vance J, Pericak-Vance M, Brown R, Rudolf G, Picard F, Alonso E, Brin M, Nemeth AH, Farrall M, Monaco AP. Choreo-acanthocytosis: genetic linkage to chromosome 9q21. Am J Hum Genet 1997 61:899-909
Farrall M, Weeks DE Mutational mechanisms for generating microsatellite allele frequency distributions: An analysis of 4,558 markers. Am J Hum Genet 1998 62:1260-1262
Garner C, Mitchell J, Hatzis T, Reittie J, Farrall M, Thein S-L Haplotype mapping of a major QTL for fetal hemoglobin production on chromosome 6q23. Am J Hum Genet 1998 62:1468-1474
Keavney B, McKenzie CA, Connell JMC, Julier C, Ratcliffe PJ, Sobel E, Lathrop M, Farrall M. Measured haplotype analysis of the angiotensin-1 converting enzyme (ACE) gene. Hum Mol Genet 1998 7:1745-1751
Munroe PB, Strautnieks SS, Farrall M, Daniel HI, Lawson M, DeFreitas P, Fogarty P, Gardiner RM, Caulfield M. Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans. Am J Hypertens 1998 11:942-945
Farrall M, Keavney B, McKenzie C, Delepine M, Matsuda F, Lathrop GM. Fine-mapping of an ancestral recombination breakpoint in DCP1. Nature Genetics 1999 23:270-271
Garner C, Tatu T, Reittie JE, Littlewood T, Darley J, Cervino S, Farrall M, Kelly P, Spector TD, Thein SL. Genetic influences on F cells and other hematological variables: a twin heritability study. Blood 2000 95:342-346
last updated January 31st 2000