 | chaos
Annotation, analysis and visualization of variants from high-throughput sequencing experiments |
Introduction
CHAoS is a Perl-based system for annotation of variants identified in high-throughput sequencing experiments developed at the Wellcome Trust Centre for Human Genetics (WTCHG).
Functionality includes annotation of variants with information relating to population genetics, known transcripts, positional records, and sequence motif-based prediction. In addition, annotated variants can be summarized and extracted to facilitate downstream analysis.
There is also basic support for gene-based biological annotation, and eventually will include tools for variant and genotype analysis and visualization.
Download
CHAoS releases can be downloaded here
Documentation
Installation instructions are included as part of the Chaos distribution (README).
Overview of usage and features can be obtained here or by running Chaos without any arguments after installation
Supplemental annotation data
| Gene function annotation files | gene_annot.tar.gz | updated 6 FEB 2012 |
| ENCODE regulatory data files | reg/ | updated 6 FEB 2012 |
Contact
Kyle Gaulton < kgaulton@gmail.com >
Manuel Rivas < rivas@broadinstitute.org >
|
