Spencer group

Vincent Pedergnana

Post-doctoral research associate


Wellcome Trust Centre for Human Genetics, Roosevelt Dr.
Oxford, OX3 7BN


Research overview

Vincent joined Chris Spencer's group in Oxford as part of the STOP-HCV consortium on the analysis of human genetic data in 2014. He is currently working with genetic data to improve health and healthcare via stratified medicine, in the context of hepatitis C infection. He is also interested in pharmacogenomics, using genetic data to uncover novel pleiotropic variants involved in the response or adverse reaction to treatment.

Before coming to Oxford, Vincent completed a PhD in genetic epidemiology at the Université Paris Descartes where he worked on the genetic susceptibility to oncogenic viruses infection in complex and mendelian diseases.


V. Pedergnana, L. Syx, A.Cobat, J.Guergnon, P.Brice, C. Fermé, P. Carde, O. Hermine, C. Le Pendeven, C. Amiel, Y. Taoufik, I. Theodorou, C. Besson, L. Abel; Combined linkage and association studies show that HLA class II variants control levels of antibodies against Epstein-Barr virus antigens; PlosOne, July 2014

V. Pedergnana, C. Martel-Jantin, J. TJ Nicol, V. Leblond, D-A. Trégouët, P. Tortevoye, S. Plancoulaine, P. Coursaget, A. Touzé, L. Abel, A. Gessain; Merkel cell polyomavirus infection occurs during early childhood and is transmitted between siblings; Journal of Clinical Virology, July 2013

V. Pedergnana, M. Abdel-Hamid, J. Guergnon, A. Mohsen, L. Le Fouler, I. Theodorou, M.K. Mohamed, A. Fontanet, S. Plancoulaine, L. Abel; Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in the spontaneous clearance of hepatitis C virus; PlosOne, May 2012

V. Pedergnana, A. Gessain, P. Tortevoye, M. Buyn, D. Bacq-Daian, A. Boland, JL. Casanova, L. Abel, S. Plancoulaine; A major locus predisposing to HHV-8 infection in children maps to chromosome 3p22 in an African population; European Journal of Human Genetics, January 2012