Dr Theodosios Kyriakou

Postdoctoral Research Fellow

Research Summary

My research interests are focused in elucidating the functional effects of genetic polymorphisms in molecular physiology. I am currently involved in a number of projects stemming from findings of Genome Wide Association studies. Currently my main focus is trying to understand the functional effects of the widely reported association on chromosome 9 with cardiovascular disease.

Publication List

Peden, J.F., Hopewell, J.C., Saleheen, D. & other authors 2011. 'A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease'. (2011) Nat Genet. Mar 6. [Epub ahead of print] View on Pubmed
Lee, A. K., Kyriakou, T. & other authors 2010. 'Functional single-nucleotide polymorphism in acetyl-CoA carboxylase ACACB gene promoter'. DNA Cell Biol 29, 703-712. View on Pubmed
Clarke, R., Peden, J. F., Hopewell, J. C. & other authors 2009. 'Genetic variants associated with Lp(a) lipoprotein level and coronary disease', N Engl J Med 361, 2518-2528. View on Pubmed
Folkersen L, Kyriakou T, Goel A, Peden J, Mälarstig A & other authors 2009. 'Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.' PLoS One. vol 2;4(11):e7677. View on Pubmed
Lee AK, Mojtahed-Jaberi M, Kyriakou T & other authors 2009. 'Effect of high-fat feeding on expression of genes controlling availability of dopamine in mouse hypothalamus.' Nutrition. [Epub ahead of print] View on Pubmed

(more)

Research Areas

Molecular biology/Functional Genomics

Keywords

Molecular Biology, Functional, Cardiovascular disease, Genomics

Contact Details

Procardis Group
The Wellcome Trust Centre for Human Genetics
University of Oxford
Roosevelt Drive
Oxford
OX3 7BN
United Kingdom

Tel 01865 287663
Fax 01865 287599
Email theo@well.ox.ac.uk

Sponsor

European Union Sixth Framework Program