Bioinformatics Group

My Home Page

Marker Selection Methods

Description of Method (PDF)

Input File Format

Running the Programs

Output

Whole Chromosome Analysis

Download C Source Code

Web Server


Wellcome Trust Centre for Human Genetics

SNP Selection Page

Download C Program Source

There are three programs available:

  • span_haplotype which finds the optimal subsets of markers by exhaustive search. This is only suitable for datasets with < 30 markers if you want the program to run in a few minutes.
  • greedy_haplotype which finds suboptimal subsets of markers by greedy search. This is suitable for all datasets. The two programs produce the similar answers on our test data
  • big_haplotype Finds good sets of markers over very large regions such as whole chromosomes, involving hundreds or thousands of markers.
  • Download gzipped C source here.
  • Installation After downloading the file as haplotype.SRC.tar, type the follwing commands:
    1. tar xvf haplotype.SRC.tar
    2. cd SRC
    3. compile.csh
    Then copy the binaries span_haplotype, greedy_haplotype, big_haplotype to somewhere on your path.

Drop me an email for more details.

 
 
spacer