Current research posts

The Henry Wellcome Building for Cellular and Molecular Physiology (HWBMP)

Research assistant in mass spectrometry and clinical proteomics

Salary Scale: Academic-Related Research Staff Grade 6

Applications are invited for a research assistant who is willing to learn novel and state-of-the art technologies for protein identification and characterisation using proteomics and biochemistry approaches. The principal focus will be devoted to the proteomic analysis of clinical samples, and the development of novel methodologies and proteomics based workflows for such clinical studies. Specifically, we are interested in examining the urine of transplant patients for BK viral products to help in diagnosis of infections and monitoring of the effects of reduction of immunosuppression.

The successful applicant will have a University degree in biochemistry, chemistry, or cell biology. The applicant must have an adaptable approach to work and willingness to tackle a variety of tasks. Knowledge of standard laboratory techniques is essential however training will be provided in all aspects of the work, especially in less standard protocols. The position is available for 1 year in the first instance and will be funded by the NHS Biomedical Research Centre Programme.

A detailed job description is available here.

To apply please send your CV, with a letter of application and the names and addresses of two referees, quoting reference H5-10-001-CW, to the Personnel Administrator, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN. Please quote the above reference number. The closing date for applications is Tuesday 9^th February 2010 with an anticipated start date of March 2010.

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POST DOCTORAL RESEARCH SCIENTIST

University Grade 7: £28,983 to a discretionary £38,951
The position is offered for 6 months in the first instance.

Applications are invited for the post of Post Doctoral Research Scientist at the Wellcome Trust Centre for Human Genetics to work on the genetics of animal behaviour and physiology. It is hoped that the appointee will be able to take up the post as soon as possible.

This is a six month post funded by the Wellcome Trust to work on the genetic architecture of neurogenesis and its relationship to behavior in mice. The project exploits advances in gene mapping pioneered at the Wellcome Trust Centre for Human Genetics, an internationally renowned centre for complex trait analysis. The job will involve genetic mapping, expression analyses, immuohistochemistry, behavioural analysis and the use of recombineering to produce vectors suitable for targeting. The successful candidate must show that s/he is capable of carrying out the necessary molecular and quantitative analyses. The post holder will have to establish good working relationships with groups working on both the molecular biology and genetic mapping components of this project.

Candidates should have a PhD in a related discipline together with previous experience of behavioural analysis in mice and proven ability with immunohistochemistry, particularly for neurogenesis, and the ability to generate targeting vectors using recombineering.

A detailed job description quoting reference H5-10-006-JF is available from the Personnel Assistant, (email: personnel@well.ox.ac.uk, tel: 01856 287507 or from our web page here.

Applications, in the form of a full and detailed CV together with the names and address of two referees, should be sent to the Personnel Assistant at the Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, or by email to; personnel@well.ox.ac.uk, or fax; 01865 287516. Please quote the reference number on your application.

Closing date for applications is Friday 19 February 2010

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The Wellcome Trust Centre for Human Genetics

Post-doctoral Research Associate in Statistical Genetics

University Grade 7: £28,983 to £35,646

We are seeking to appoint a Post-doctoral Research Associate in Statistical Genetics to join Dr. Eleftheria Zeggini's group based at the Wellcome Trust Centre for Human Genetics and the Wellcome Trust Sanger Institute. The successful applicant will form part of a team working to understand the role of rare variants in common complex disease. This position will be based at the Wellcome Trust Sanger Institute, Cambridge.

The successful candidate will be appointed as part of a Pfizer-funded project, and will have overall responsibility for the statistical analysis of this high-profile study, including liaison with, and reporting to the full range of collaborative partners. We are looking to appoint someone with strong analytical skills and a relevant postgraduate degree. Experience in the generation, management and analysis of simulated genetic datasets is essential.

The post is available for 12 months in the first instance. Excellent facilities are available and there is a strong commitment to personal and professional development within the group. A detailed job description quoting reference H5-10-008-EZ is available from by clicking here

Applications, including a full CV, the names and addresses of at least two referees, and a cover letter setting out, with examples, how you meet the selection criteria, should be sent to the Personnel Office, email: personnel@well.ox.ac.uk.

Informal enquiries can be made to Eleftheria@sanger.ac.uk

The closing date for applications is Friday 5^th March 2010.