HR

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UNIVERSITY OF OXFORD
POSTDOCTORAL RESEARCH SCIENTIST IN STATISTICAL FUNCTIONAL GENOMICS WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 7: Salary in the range £ 31,076- £34,956 p.a.

Applications are invited for the position of Postdoctoral Research Scientist in Statistical Functional Genomics in the Julian Knight group based at the Wellcome Trust Centre for Human Genetics.

We seek a highly motivated, proactive individual who will benefit from the exceptional research environment for functional genomics, bioinformatics and statistical genetics found at the Wellcome Trust Centre for Human Genetics. You will play a key role leading bioinformatic analysis of functional genomic data generated through this programme in patient samples and controls.  You will analyse high throughput Next Generation Sequencing (NGS) data sets quantifying gene expression (RNA-seq) as well as SNP array data, seeking to define the nature of genetic variation in the populations studied and to functionally annotate variants in the setting of high dimensional clinical data. Your work will include mapping gene expression as a quantitative trait (eQTL mapping) to identify SNP associations with differences in expression.

You will have a PhD in Bioinformatics, Statistical genetics, Statistics, Mathematics, Physics, Computer Science or a related discipline together with experience of functional genomic analysis and experience of, and demonstrated competence in, scientific computing using at least one programming language. You will also have excellent analytical and quantitative skills and the ability to work in a team and a good publication record.

The position is funded by Specialist Diabetes Research and Treatment Centre LLC and is fixed term for 1 year.

To apply for this role and for further details, including a job description and a person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/127336-Postdoctoral-Research-Scientist-in-Statistical-Functional-Genomics

Only applications received before 12:00 midday on Monday 27 February 2017 will be considered.

Please quote ref. 127336 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD
RESEARCH ASSISTANT IN HIGH-THROUHPUT GENOMICS
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 6: £27,629 to £32,958 with a discretionary range to £36,001 p.a.

Applications are invited for a Research Assistant in High-Throughput Genomicsto work at the Wellcome Trust Centre for Human Genetics.

You will carry out service projects in accordance with Standard Operating Procedures involving sample handling and performing complex experimental procedures using High Throughput Array and High Throughput Sequencing technologies.

You will undertake genotyping, epigenetic or sequencing projects assigned by project manager(s) as part of the service work and you will provide assistance and troubleshooting to users of the High Throughput Genomics Service within the Centre.

You will have a BSc in Biological Sciences with demonstrable knowledge in molecular biology. You will have experience of performing complex experimental procedures following SOPs, with demonstrable manual dexterity and respect for precision high cost equipment. You will have the ability to organize and prioritize work efficiently, delivering results to a high standard and to an agreed schedule. You will be able to demonstrate a high level of communication skills, both written and oral, and the ability to work effectively within a team.

The position is funded by Genomic Services Income and is fixed-term for 12 months in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/127422-Research-Assistant-in-High---Throughput-Genomics

Only applications received before 12.00 midday on Monday, 6th March 2017 can be considered. Please quote reference 127422 on all correspondence.

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UNIVERSITY OF OXFORD
PART-TIME QUALITY MANAGER IN HIGH-THROUGHPUT GENOMICS
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 7: £31,076 to £38,183 with a discretionary range to £41,709 p.a.

Part time up to 22.5 hour per week

Applications are invited for a Part-time Quality Manager in the High Throughput Genomics group based at the Wellcome Trust Centre for Human Genetics.

We are looking for a highly motivated individual with experience of quality management to join the team and continue to build on our quality management systems. Your primary role will be to identify and apply relevant elements of ISO15189  to the work undertaken by the High Throughput Genomics (HTG) group. You will develop a Quality Management System for the HTG group that is tailored to their specific needs of genomic service work for academic and clinical customers. You will be required to maintain an up to date copy of the relevant regulations i.e. ISO15189 and ensure the HTG group is compliant with the agreed quality policies for the scope of any work undertaken.

You will have a BSc in Biological Sciences or equivalent qualification / relevant experience with demonstrable knowledge of quality management systems. You will have the ability to organize and prioritize work efficiently, delivering results to a high standard and to an agreed schedule. You will be able to demonstrate a high level of communication skills, both written and oral, and the ability to work effectively within a team.

The position is funded by Genomic Services Income and is fixed-term for two years in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/126423-Part---time-Quality-Manager-in-High---Throughput-Genomics

Only applications received before 12.00 midday on Wednesday, 15th March 2017 can be considered. Please quote reference 126423 on all correspondence.

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UNIVERSITY OF OXFORD
POSTDOCTORAL RESEARCH FELLOW IN THE MOLECULAR GENETICS OF CANCER
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 7.1: £31,076 p.a

Applications are invited for a Postdoctoral Research Fellow in the Molecular Genetics of Cancer to join Professor Ian Tomlinson group. The group’s main interests are susceptibility to cancer and related diseases, functional analysis of cancer genes, and the roles of selection and genomic instability in tumour evolution.

You will work on exploration of germline and somatic cancer driver mutations in patients and their tumours, including in situ analysis. The responsibilities will be varied, but will include sample collection and preparation, experiments on cancer gene function and the analysis of genomic data from patients and their tumours. Technical, academic and analytical/computational ability is required, together with enthusiasm and a high quality of work. 

You will have an honours degree and PhD in a relevant subject with experience in cancer diagnostics and/or a medical qualification, demonstrable ability to liaise with clinicians and demonstrable academic and technical ability. You will have experience of the genetic analysis of human diseases, including cancer; experience of other techniques of cancer analysis, specifically including western blotting and immunohistochemistry and specific expertise in the pathobiology of colorectal cancer.

You will also be able to demonstrate commitment to high standards, including record keeping and have good oral, written and electronic communication skills. You will need to be able to work both as part of a team and with some degree of independence and a demonstrable interest in medical research is desirable. Full Selection Criteria are provided in the Job Description (see below).

The position is fixed-term from 1st April 2017 to 31st May 2018, with possible extension thereafter depending on available grant funding and funded by ERC award INSITUMUT.

Applications for this position are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/127581-Postdoctoral-Research-Fellow-in-the-Molecular-Genetics-of-Cancer

Only applications received before 12.00pm on Monday, 20 March 2017 can be considered. Please quote ref. 127581 on all correspondence.

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