HR

Research Positions

 

 

 

 

UNIVERSITY OF OXFORD
RESEARCH ASSISTANT - CANCER RESEARCH UK DISCOVERY AWARD
DIVISION OF STRUCTURAL BIOLOGY, WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN

Grade 6: £26,527 - £31,644 p.a. (with a discretionary range to £34,565 p.a.)

Applications are invited for a Research Assistant to join a project funded by a new Discovery Award jointly made to Dr Robert Gilbert of the Division of Structural Biology, and Professor Chris Norbury of the Sir William Dunn School of Pathology.

Dr Gilbert’s and Professor Norbury’s groups make use of structural and cell biology and molecular genetics techniques to study the mechanisms of tumour suppressor miRNA biogenesis. The focus of this project is the screening of small compound libraries for leads that inhibit the yeast and human isoforms of the uridylyltransferases involved. You will join a very lively and motivated international and interdisciplinary group of scientists.

You will have a good BSc or equivalent in a relevant subject. You will have research experience in at least one of the following areas: Protein expression and purification; Enzymatic assays, ideally including inhibitor identification; Alpha screen assays. You will have the ability to deliver results to the required standard and schedule. You will be able to demonstrate your ability to work independently as well as in a team and to manage the day-to-day running of a research project. 

The position is funded by Cancer Research UK and is fixed-term for 1 year in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112274

Only applications received before, 12:00 midday on Monday 28th April 2014 can be considered. Please quote ref. 112274 on all correspondence.

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UNIVERSITY OF OXFORD
POSTDOCTORAL RESEARCH SCIENTIST - CANCER RESEARCH UK DISCOVERY AWARD
DIVISION OF STRUCTURAL BIOLOGY, WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 7: £29,837 - £36,661 p.a. (with a discretionary range to £40,046 p.a.)

Applications are invited for a Postdoctoral Research Scientist to join a new project funded by a Discovery Award jointly made to Dr Robert Gilbert of the Division of Structural Biology, and Professor Chris Norbury of the Sir William Dunn School of Pathology.

Dr Gilbert’s and Professor Norbury’s groups make use of structural and cell biology and molecular genetics techniques to study the mechanisms of tumour suppressor miRNA biogenesis. The focus of this project is the screening of small compound libraries for leads that inhibit the yeast and human isoforms of the uridylyltransferases involved. You will join a very lively and motivated international and interdisciplinary group of scientists.

You will have a PhD/DPhil in a relevant subject. You will have research experience in at least one of the following areas: Protein expression and purification; Enzymatic assays including inhibitor identification; Alpha screen assays. You will have a good publication record, with documented examples of recent work at the level of first author publication in a leading refereed journal. You will have the ability to manage the day-to-day running of a research project including assisting the work of junior researchers, and will have good communication skills, including the ability to present work at international symposia and to non-specialist audiences. You will have the ability to deliver results to the required standard and schedule. You will be able to demonstrate your ability to work independently as well as in a team and to manage the day-to-day running of a research project.

The position is funded by Cancer Research UK and is fixed-term for 1 year in the first instance 

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112275

Only applications received before, 12:00 midday on Monday 28th April 2014 can be considered. Please quote ref. 112275 on all correspondence.

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UNIVERSITY OF OXFORD                                                                                RESEARCH ASSOCIATE IN STATISTICAL SEQUENCE ANALYSIS                                   WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 7: £29,837 - £33,562 p.a.

Applications are invited for a Research Associate in Statistical Sequence Analysis to join the Lunter and McVean groups at the Wellcome Trust Centre for Human Genetics. The Wellcome Trust Centre is at the forefront of international research in clinical and fundamental human genetic research, and has been particularly successful in applying next-generation high-throughput sequencing to these research areas.  As a result the Centre has world-class sequence analysis capabilities, and seeks to invest more into this area.

This post is dedicated to developing tools to analyse sequencing data generated by Oxford Nanopore’s MinION and GridION devices.  These devices generate very long read lengths, which sets them apart from existing sequencing platforms, and promises to enable new research and clinical applications including on-site diagnosis and detection of large structural variation.  However, the data requires careful error modeling and processing.

You will have a first degree in statistics, computer science, physics or maths and a strong affinity with statistical methodology, algorithm design and the C and Python/Perl programming. Experience with the analysis of very large data sets and with high-throughput sequence data would be an advantage. You will also have the ability to manage the day-to-day running of a research project, have good communication skills, including the ability to present work at group meetings and the ability to work both independently and as part of a team.

The post is fixed-term for two years in the first instance and funded by Biotechnology and Biological Sciences Research Council (BBSRC).

To apply for this role and for further details, including a job description and a person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112848

Only applications received before 12:00 midday on Wednesday 7th May 2014 will be considered. Interviews will take place on Friday 16th May 2014.

Please quote reference 112848 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD                                                                                         POSTDOCTORAL RESEARCH SCIENTIST IN SINGLE CELL GENOMICS                         WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 7: £29,837 - £36,661 p.a. (with a discretionary range to £40,046 p.a.)

Applications are invited for a Postdoctoral Research Scientist in Single Cell Genomics to join a newly established Applied Statistical Genomics research group headed by Dr Christopher Yau based at the Wellcome Trust Centre for Human Genetics. The research will focus on the development of novel statistical methodology for the analysis of large-scale single cell genomics data and offers an opportunity to be at the analytical forefront of institutional expansion in this area. The work will be supported by an Oxford-Stanford Big Data in Human Health Seed Grant.

The position would suit a candidate who is interested in developing a career at the interface of Statistics and the Biosciences. Ideally, you will have experience of statistical methods development gained through a recently obtained (or soon to be) PhD (or equivalent) in a quantitative subject (e.g. Mathematics, Statistics, Physics, Engineering or Computer Science). Experience of Bayesian Statistics and machine learning techniques is highly desirable as is evidence of prior experience of developing bioinformatics software and/or analysing genomic data sets.

You will be able to work as part of a team and independently and deliver results to the required standard and schedule. You should also possess the ability to organise and prioritise your own work with minimal supervision and have excellent communication skills, both written and oral. The post will involve interactions with collaborators from across multiple scientific areas.

The post is fixed-term for two years in the first instance and funded by the Wellcome Trust Institutional Strategic Support Fund.

To apply for this role and for further details, including a job description and a person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112695

Only applications received before 12:00 midday on Wednesday 7th May 2014 will be considered.

Please quote reference 112695 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD                                                                                           POSTDOCTORAL RESEARCH SCIENTIST IN GENOME ENGINEERING                              WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 7: £29,837 - £36,661 p.a. (with a discretionary range to £40,046 p.a.)

Applications are invited for a Postdoctoral Research Scientist in Genome Engineering to assist in the establishment of a new core cell culture facility within Dr. Ben Davies’ group at the Wellcome Trust Centre for Human Genetics.

We seek an individual with expertise in the culture of human iPS or human ES cells who will supervise the day-to-day running of the facility, will provide training and assistance for centre researchers working within the facility, will design and conduct service projects for the genetic manipulation of iPS cells and will work together with the transgenic core to explore technological improvements in the use of site specific nuclease technology (TALENs and CRISPR). We anticipate the role to be exceptionally diverse and would suit an individual with proven expertise in human stem cell culture who is enthusiastic and motivated to move to a service oriented role within a core facility.

You will have a PhD in molecular biology, biochemistry, genetics or a related discipline (or expectation that the thesis will be submitted before July 2014). You will also have experience in the culture of human iPS or human ES cells and experience in the genetic manipulation (stable / transient transfection) of cells with a strong motivation to work in problems related to human and mammalian genetics.

You will have the ability to deliver results to the required standard and schedule. You will be able to demonstrate your ability to work independently as well as in a team and to manage the day-to-day running of a research project.

The position is funded by Wellcome Trust and is fixed-term for 2 years in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112784

Only applications received before, 12:00 midday on Wednesday 14th May 2014 can be considered. Interviews will take place in week commencing 26th May. Please quote ref. 112784 on all correspondence.

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UNIVERSITY OF OXFORD                                                                                                 RESEARCH ASSOCIATE IN STATISTICAL AND POPULATION GENETICS (TWO POSTS)WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 7: £29,837 to £36,661 with a discretionary range to £40,046 p.a.

Applications are invited for a Research Associate in Statistical and Population Genetics to work at the Wellcome Trust.

Up to two positions are available to work on the analysis of genetic variation data across a range of projects, including the development of methods for genealogical inference, the analysis of HLA-pathogen interactions and the comparative study of mutation rates. You will help in the design of experiments, the development of statistical and computational methods for analysing data, interpretation of project data, the dissemination of methodology and results and participate in collaborations with specific partners and international consortia.

You will have a PhD with a strong quantitative or computational element and good publication record as well as excellent skills in statistical programming (preferentially R). You should have experience of analysing large data sets and experience of scripting (Python or Perl).

The position is funded by the Wellcome Trust and is fixed-term for 3 years in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112693

Only applications received before 12.00 midday, on Wednesday 21st May 2014 can be considered. Please quote reference 112693 on all correspondence.

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UNIVERSITY OF OXFORD                                                                                                    SENIOR RESEARCH ASSOCIATE IN STATISTICAL AND POPULATION GENETICS (TWO POSTS)                                                                                                                            WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 8: £37,756 to £45,053 with a discretionary range to £49,216 p.a.

Applications are invited for a Senior Research Associate in Statistical and Population Genetics to work at the Wellcome Trust Centre for Human Genetics in the group of Gil McVean, Professor of Statistical Genetics.

Up to two posts are open to work on the analysis of genetic variation data across a range of projects, including the comparative study of mutation rates, global patterns of genetic diversity in the HLA and methods for analysing high throughput sequencing data. You will help in the design of experiments, the development of statistical and computational methods for analysing data, interpretation of project data, supervision of junior group members, the dissemination of methodology and results and participate in collaborations with specific partners and international consortia.

You will have a PhD with a strong quantitative or computational element, a good publication record and skills in statistical programming (preferentially R). You should have experience of analysing large data sets and experience of scripting (Python or Perl).

The position is funded by the Wellcome Trust and is fixed-term for 3 years in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112808

Only applications received before 12.00 midday, on Wednesday 21st May 2014 can be considered. Please quote reference 112808 on all correspondence.

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UNIVERSITY OF OXFORD                                                                                                          RESEARCH ASSISTANT IN HIGH-THROUGHPUT GENOMICS                                                      WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                        Grade 6: £26,527 - £31,644 with a discretionary range to £34,565p.a.

Applications are invited for a Research Assistant in High-Throughput Genomics to work at the Wellcome Trust Centre for Human Genetics.

You will carry out service projects in accordance with Standard Operating Procedures requiring you to perform complex experimental procedures using High-Throughput Sequencing and Array technologies, in particular Illumina platforms and applications.  You will provide assistance and troubleshooting to users of the High Throughput Genomics Service within the Centre.

You will have a BSc in Biological Sciences with demonstrable knowledge of molecular biology. You will have experience of performing complex experimental procedures following SOPs with in-depth knowledge and ideally experience of High Throughput Array and Sequencing technology, in particular Illumina platforms and applications. You will have the ability to organize and prioritize work efficiently delivering results to required standard and to an agreed schedule alongside with demonstrable high level of communication skills both written and oral and ability to work effectively as part of a large team.

The position is funded by revenue from the High-Throughput Genomics group business plan and is fixed-term for 1 year in the first instance.

Applications for this vacancy are to be made online. To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112866

Only applications received before 12.00 midday on Thursday 22nd May 2014 can be considered. Please quote reference 112866 on all correspondence.

You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD                                                                                                 POSTDOCTORAL RESEARCH SCIENTIST IN SINGLE-CELL FACILITY                                    WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                                           Grade 7: £29,837 - £36,661p.a. with a discretionary range to £40,046p.a.

Applications are invited for a postdoctoral research ccientist in the new Single-Cell Facility, working within the High-Throughput Genomics Group at the Wellcome Trust Centre for Human Genetics (WTCHG).

You will be responsible for the practical aspects of setting up and running a new facility within the High-Throughput Genomics Group at the WTCHG (Oxford Genomics Centre). You will be able to work independently in solving logistical, technical and scientific problems, with the full support of senior staff. Combining cell and tissue handling (culture, isolation, cell sorting) with preparation of samples for high-throughput sequencing, qPCR and other methods of obtaining single-cell data, you will  likely have substantial experience in both cell culture and these detailed, high-throughput molecular biology protocols. You will work closely with investigators from many research groups and you will contribute directly to the scientific success of the projects on which you work.

The position is funded by revenue from the High-Throughput Genomics group business plan and is fixed-term until 31st March 2016.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=112865

Only applications received before 12.00 midday, on Thursday 22nd May 2014 can be considered. Please quote reference 112865 on all correspondence.

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