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University of Oxford
Senior Postdoctoral Bioinformatician in Diabetes Genetics
Wellcome Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN / Oxford Centre for Diabetes Endocrinology & Metabolism, Churchill Hospital, Headington, Oxford, OX3 7LE
Grade 8: £39,992 - £47,722 with a discretionary range to £52,132 per annum

Applications are invited for a Senior Postdoctoral Bioinformatician in Diabetes Genetics at the University of Oxford. You will be based at the Wellcome Centre for Human Genetics and the Oxford Centre for Diabetes Endocrinology & Metabolism.

The principal focus of this work will be related to the detection and functional characterization of genetic variants associated with type 2 diabetes and related traits, including the complications of diabetes. In this post, you will provide leadership in developing and implementing a wide range of statistical and bioinformatics approaches within a multi-disciplinary team. The post involves responsibility for the integrated analysis of multiple, complex data sets to which we have access (including genetic, epigenomic, proteomic, metabolomic, physiological and clinical data), to address questions of mechanistic inference and translational value.

You will hold a PhD or equivalent degree in a relevant scientific subject with extensive, relevant, experience as a postdoctoral research in academia, biotech, or pharma. You will have demonstrable experience in the analysis of large-scale, highly-dimensional scientific data including those generated by GWAS, exome/whole genome sequencing and sequence-based functional assays (e.g. RNA-Seq, ATAC-Seq). You will have experience in the integration of diverse large-scale datasets, understanding of the key biological systems perturbed in type 2 diabetes, and be highly proficient in the use of  programming and scripting languages (Unix, R, PERL, Python). Experience in network analysis and deep-learning approaches would be desirable. You will have a strong publication record for your career stage, proven ability to supervise staff and students and experience of developing scientific techniques and/or computational pipelines.

This position is fixed term for two years in the first instance and funded by NIH, Foundation of the NIH and the European Union.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/133769-Senior-Postdoctoral-Bioinformatician-in-Diabetes-Genetics

Only applications received before 12:00noon on Monday 23 April 2018 can be considered.

Please quote ref. 133769 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

 

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University of Oxford
Postdoctoral Research Scientist in Diabetes Genetics
Wellcome Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN / Oxford Centre for Diabetes Endocrinology & Metabolism, Churchill Hospital, Headington, Oxford, OX3 7LE
Grade 7: £31,076 - £38,183 with a discretionary range to £41,709 per annum                                                                                                                                     

Applications are invited for a Postdoctoral Research Scientist in Diabetes Genetics at the University of Oxford. You will be based at the Wellcome Centre for Human Genetics and the Oxford Centre for Diabetes Endocrinology & Metabolism.

You will form part of a highly-productive multi-disciplinary team leading international efforts to characterize the genetic basis of type 2 diabetes and its complications through use of large-scale genetic and genomic data. You will have responsibility for the analysis and interpretation of a wide range of data, including those generated from genome-wide genotyping arrays, whole-genome sequence, and functional sequencing data (e.g. RNA-Seq, ATAC-Seq).  Applications for this post should make explicit the extent to which existing computational and statistical skills will ensure immediate productivity.  

You will hold (or be in the process of completing) a Ph.D/D.Phil in biochemistry, molecular biology or a closely related field with associated research experience. You will have demonstrable experience in the QC and analysis of large-scale genetic and genomic data. This might for example relate to genome-wide or exome array data including imputation with sequence-based reference panels and use of meta-analysis software. You will be expected to understand the key biological systems perturbed in type 2 diabetes, and have strong computational skills including familiarity with programming and scripting languages (Unix, R, PERL, Python). It is essential that you have excellent communication skills to support your integration within a multidisciplinary, international team. You will also have sufficient specialist knowledge to be able to work independently, to identify major challenges and obstacles to the realisation of scientific objectives, and to set out strategies to overcome them. 

This position is fixed term for two years in the first instance and funded by NIH and the European Union. 

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/133669-Postdoctoral-Research-Scientist-in-Diabetes-Genetics

Only applications received before 12:00noon on Monday 23 April 2018 can be considered.

Please quote ref. 133669 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

 

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Viral Vector Core Facility Manager
Viral Vector Core Facility, Jenner Institute located at the Wellcome Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN
Grade 8: £39,992 - £47,722 with a discretionary range to £52,132 per annum

INTERNAL APPLICATIONS ONLY.

Applications are invited for a Viral Vector Core Facility Manager in Viral Vector Core Facility (VVCF) at the Jenner Institute located at the Wellcome Centre for Human Genetics.

We are seeking an intelligent and motivated post-doctoral scientist with relevant laboratory experience as well as experience of managing others. You will have experience of managing junior staff, and of devising and implementing systems to ensure high productivity coupled with quality assurance. You will have knowledge of the standard molecular biological techniques (plasmid purification, cloning, PCR, etc) as well as experience of mammalian cell culture. Knowledge of virological culture techniques (adenovirus and poxviruses) or the manipulation of viral genomic clones will be required. Training will be available in all aspects of the laboratory work, especially in the less standard protocols, but an ability to work without supervision and to combine a structured and organised approach with enthusiasm will be important. You must have an adaptable approach to work and a willingness to tackle a variety of tasks. Good record-keeping skills are essential.

You will have a PhD in a relevant discipline with mmanagement experience, laboratory experience in molecular biology and cell culture and practical experience of virological techniques, especially adenovirus or poxvirus culture. You will work closely with others as part of a team, while taking personal responsibility for assigned tasks. You are expected to have a responsible nature with a methodical and careful approach to laboratory work and the ability to communicate results clearly and logically.

The position is funded by the Department and is fixed-term until 31st October 2019 in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/134221-Viral-Vector-Core-Facility-Manager

Only applications received before 12.00noon on Monday 23 April 2018 can be considered.

Please quote reference 134221 on all correspondence.