Research jobs                             

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University of Oxford
Research Assistant in Colorectal Cancer

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN
Grade 6: Salary in range £28,098 to £31,604 per annum

Applications are invited for a Research Assistant in Colorectal Cancer to work at the Wellcome Trust Centre for Human Genetics.

You will work in cancer and human genetics, including sample preparation, library preparation for sequencing, genotyping, mutation screening and analysis, mouse colony curation, undertaking basic procedures of husbandry, cell culture and analysis, tissue preparation and analysis, functional assays and other work as necessary.

You will have a degree in Molecular Biology or in a relevant subject with an experience of basic methods of molecular genetics. You will have the ability to organize and prioritize work efficiently, delivering results to a high standard and to an agreed schedule. You will be able to demonstrate a high level of communication skills, both written and oral, and the ability to work effectively within a team.

The position is funded by the National Institute of Health (NIHR) and is fixed-term until the end of September 2019 in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130299-Research-Assistant-in-Colorectal-Cancer

Only applications received before 12.00 midday on Tuesday, 19 September  2017 can be considered. Please quote reference 130299 on all correspondence.

 

 

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University of Oxford
Research Assistant in High-Throughput Genomics
Wellcome Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN
Grade 6: £28,098 to £33,518 with a discretionary range to £36,613 p.a.

Applications are invited for a Research Assistant in High-Throughput Genomics to work at the Wellcome Trust Centre for Human Genetics.

You will carry out service projects, primarily in Next-Generation Sequencing, in accordance with Standard Operating Procedures for sample handling and performing complex experimental procedures.

You will work to strict deadlines on a wide variety of genomics applications assigned by the Library Team manager. You will also work closely with senior scientists to ensure that projects progress smoothly through established pipelines, keeping accurate records with a variety of laboratory information management systems.

You will have a BSc in Biological Sciences with demonstrable knowledge in molecular biology. You will have experience of performing complex experimental procedures following SOPs, with demonstrable manual dexterity and respect for precision high-cost equipment. You will have the ability to organize and prioritize work efficiently, delivering results to a high standard and to an agreed schedule. You will be able to demonstrate a high level of communication skills, both written and oral, and the ability to work effectively within a team.

The position is funded by Genomic Services Income and is fixed-term for 12 months in the first instance.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130687-Research-Assistant-in-High-Throughput-Genomics

Only applications received before 12.00 midday on Wednesday, 27 September 2017 can be considered. Please quote reference 130687 on all correspondence.

 

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University of Oxford
Postdoctoral Research Scientist in Immunogenomics

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade 7: Salary in range £31,604 to £35,550 p.a.

Applications are invited for a Postdoctoral Research Scientist in Immunogenomics to join an established team with a track record of innovation and high impact research in the functional genomics of immunity led by Professor Julian Knight at the Wellcome Trust Centre for Human Genetics (WTCHG).

We seek a postdoctoral researcher with the ability to use immunological methods in the setting of a genomics programme to address challenging, cutting-edge scientific questions. You will use your skills and experience to play a key role in research to investigate the functional basis of extreme innate immune response phenotypes contributing to disease, building on our recent work in this area (Science 2014, Lancet Respiratory Medicine 2016). The goal is to advance understanding of the functional alleles driving such differences between individuals, their mechanism of action and their biological consequences in terms of gene regulation, pathophysiology and therapeutic opportunities. You will define and functionally characterise specific genes and alleles, and perform the required immune phenotyping and cellular assays. Your work will define the landscape of variable gene regulation in the extreme innate immune response within which disease associated variants act and establish mechanism.

You will hold a PhD, or in exceptional cases expected to obtain soon, in genetics, biochemistry, molecular biology or related field with a demonstrable interest in the research described here. You will have experience of immunology and molecular biology techniques. Experience of functional genomics is desirable. You will have sufficient specialist knowledge to be able to work independently, to identify major challenges and obstacles to the realisation of scientific objectives, and to set out strategies to overcome them. You will also have a strong publication record and motivation to work in a stimulating and ambitious research environment and demonstrable high level of communication skills both written and oral.

We are currently recruiting to 3 posts for this new programme including this position, a Postdoctoral Research Scientist in Functional Genomics of Immunity (vacancy ref. 130843) and a Research Assistant in Functional Genomics (vacancy ref. 130844). If you wish to be considered for any of these other posts please submit a separate application for the relevant post.

The position is funded by the Wellcome Trust and is fixed term until 30th September 2022.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130845-Postdoctoral-Research-Scientist-in-Immunogenomics

Only applications received before 12:00 midday on Monday, 2 October 2017 can be considered.

Please quote ref. 130845 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

 

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University of Oxford
Research Assistant in Functional Genomics

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade 6: Salary in range £28,098 to £31,604 p.a. 

Applications are invited for a Research Assistant in Functional Genomics to join an established team with a track record of innovation and high impact research in the functional genomics of immunity led by Professor Julian Knight at the Wellcome Trust Centre for Human Genetics (WTCHG).

We seek a highly motivated, organised and proactive individual who will benefit from the exceptional research environment at WTCHG. You will play a key role in an exciting new research programme to investigate the functional basis of extreme innate immune response phenotypes contributing to disease, building on our recent work in this area (Science 2014, Lancet Respiratory Medicine 2016). The goal is to advance understanding of the functional alleles driving such differences between individuals, their mechanism of action and their biological consequences  in terms of gene regulation, pathophysiology and therapeutic opportunities. You will be responsible for managing the ongoing sample collection, delivering cell culture and cell purification work together with cloning, sequencing and general molecular biology. You will also play a role in the application of different ‘omic approaches and immunological assays to samples together with opportunities to functionally characterise putative regulatory variants.

You will have a degree in genetics, biochemistry, molecular biology or related field and a demonstrable interest in the research described here. You will also have an experience in standard molecular biology techniques as well as having demonstrable high level of communication skills, both written and oral, and the ability to organize and prioritise work to efficiently deliver results to the required standard and to an agreed schedule. You will be motivated by a stimulating and ambitious research environment with a desire to deliver high quality cutting-edge science and work in a laboratory offering the opportunity for career development and acquiring new expertise.

We are currently recruiting to 3 posts for this new programme including this position, a Postdoctoral Research Scientist in Functional Genomics of Immunity (vacancy ref. 130843) and Postdoctoral Research Scientist in Immunogenomics (vacancy ref. 130845). If you wish to be considered for any of these other posts please submit a separate application for the relevant post.

The position is funded by the Wellcome Trust and is fixed term until 30th September 2022.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130844-Research-Assistant-in-Functional-Genomics

Only applications received before 12:00 midday on Monday, 2 October 2017 can be considered.

Please quote ref. 130844 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

 

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University of Oxford
Postdoctoral Research Scientist in Functional Genomics of Immunity

Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford, OX3 7BN Grade 7: Salary in range £31,604 to £35,550 p.a.

Applications are invited for a Postdoctoral Research Scientist in Functional Genomics of Immunity to join an established team with a track record of innovation and high impact research in the functional genomics of immunity led by Professor Julian Knight at the Wellcome Trust Centre for Human Genetics (WTCHG).

We seek a postdoctoral researcher who is motivated by the opportunity to do outstanding science using recent advances in functional genomics involving induced pluripotent stem cells and genome editing applied to translational research questions. This will be a key component of an exciting new research programme to investigate the functional basis of extreme innate immune response phenotypes contributing to disease, building on our recent work in this area (Science 2014, Lancet Respiratory Medicine 2016). The goal is to advance understanding of the functional alleles driving such differences between individuals, their mechanism of action and their biological consequences  in terms of gene regulation, pathophysiology and therapeutic opportunities. You will undertake laboratory work to investigate the functional genomics of the extreme innate immune response and the impact of genetic variation, leveraging the opportunities afforded by induced pluripotent stem cells and high-throughput screens using CRISPR and screening assays together with functional characterisation of specific genes and functional alleles to establish mechanism using appropriate molecular and functional genomic approaches.

You will hold a PhD, or in exceptional cases expected to obtain soon, in genetics, biochemistry, molecular biology or related field and a demonstrable interest in the research described here. You will have demonstrated excellence in molecular biology and functional genomics laboratory techniques. You will have sufficient specialist knowledge to be able to work independently, to identify major challenges and obstacles to the realisation of scientific objectives, and to set out strategies to overcome them. You will also have a strong publication record and motivation to work in a stimulating and ambitious research environment.

We are currently recruiting to 3 posts for this new programme including this position, a Postdoctoral Research Scientist in Immunogenomics  (vacancy ref. 130845) and a Research Assistant in Functional Genomics (vacancy ref. 130844). If you wish to be considered for any of these other posts please submit a separate application for the relevant post.

The position is funded by the Wellcome Trust and is fixed term until 30th September 2022.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130843-Postdoctoral-Research-Scientist-in-Functional-Genomics-of-Immunity

Only applications received before 12:00 midday on Monday, 2 October 2017 can be considered.

Please quote ref. 130843 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

 

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