Research Positions

UNIVERSITY OF OXFORD
QUANTITATIVE FLUORESCENCE MICROSCOPY POSTDOCTORAL FELLOW
THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS AND DIVISION OF STRUCTURAL BIOLOGY, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 7: £29,541 - £36,298 with a discretionary range to £39,649 p.a.

Applications are invited for a Quantitative Fluorescence Microscopy Postdoctoral Fellow to work jointly with Dr Sergi Padilla-Parra’s group and Prof E. Yvonne Jones’ group.

You will be developing new methodologies in advanced fluorescence microscopy to be applied to specific biological problems related to cell-cell communication and signalling systems. You will develop novel quantitative fluorescence microscopy approaches working closely with the Cellular Imaging Group at the WTCHG. Innovative methods will be developed using novel fluorescent proteins, FRET standards (i.e. donor-acceptor tandems) and labelling strategies (for example using Snap-Tag technology). In collaboration with Prof Jones’ group you will apply these novel approaches in integrated structural and cellular level analyses of the molecular mechanisms responsible for cell-cell communication.

You will have a PhD/ DPhil in biophysics, physics or engineering or in a relevant discipline. You will have a strong publication record and familiarity with the existing literature and research in the field. You will have knowledge and experience of the recent technical advances in FLIM, FCCS and super resolution light microscopy in programming and hardware device control. Strong programming skills with Matlab or similar platforms are required to integrate all Image analysis (FLIM, FCCS, SPT and Localisation Microscopy) into one easy-to-use software for the Cellular Imaging group. You will have significant experience in digital imaging and data analysis (both with commercial and custom made software)

The post is funded by the Medical Research Council and the Wellcome Trust and is available for 2 years in the first instance.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=109947

Only applications received before 12:00 midday on Friday 18^thOctober 2013 can be considered.

Please quote reference 109947 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD
MalariaGEN PRINCIPAL BIOINFORMATICIAN
THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 8: £37,382 - £44,607 with a discretionary range to £48,729 p.a.

MalariaGEN is a data-sharing community working to develop new tools to control malaria by integrating epidemiology with genome science. The resource centre that supports MalariaGEN is based at both the Sanger Institute near Cambridge and at the Wellcome Trust Centre for Human Genetics at the University of Oxford.

MalariaGEN aims to produce global data on natural genetic variation in parasite, mosquito and human populations, and to deliver these data via the MalariaGEN website, alongside web tools which add value by enabling people to explore, understand and analyse the data. Some of these web and data products are intended for unrestricted use by the malaria research and public health community, to inform future research directions and malaria control policy. Other web and data products are being developed for private use by researchers contributing to MalariaGEN community projects, and provide a key incentive to participation in MalariaGEN.

We have an opportunity for a MalariaGEN Principal Bioinformatician to take a key role in our bioinformatics programme, specifically in the project management of one or more data analysis pipelines relating to genome sequencing, genotyping and population genetic data from Plasmodium, Anopheles and human populations. You will have a good first degree in a scientific, computing or numerate subject with post-doctoral or equivalent professional experience working in a bioinformatics role. Strong communication skills and willingness to work collaboratively in a team setting are essential.

This position is funded by the Wellcome Trust and is available for 2 years in the first instance.

To apply for this role and for further details, including
a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=110223

Only applications received before 12:00 midday on 12:00 midday on Monday 4^th November 2013 can be considered.

Please quote ref. 110223 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERISTY OF OXFORD
MalariaGEN BIOINFORMATICIAN
THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINTON, OXFORD, OX3 7BN
Grade 7: £29,541 - £36,298 with a discretionary range to £39,649 p.a.

We have an opportunity for a MalariaGEN Bioinformatician. Your role will be key in the design, implementation and evaluation of new analytical methods, and the design, implementation and operation of analysis pipelines. This relates to genome sequencing, genotyping and population genetic data from Plasmodium, Anopheles and human populations. You will work closely with other informatics and analysis specialists in our team and with partners within and beyond the Institute. You will have a good first degree in a scientific, computing or numerate subject with experience of applied statistics and statistical computing. Strong communication skills and willingness to work collaboratively in a team setting are essential.

This position is funded by the Wellcome Trust and is available for 2 years in the first instance.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=110217

Only applications received before 12:00 midday on Monday 4^th November 2013 can be considered.

Please quote ref. 110217 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD POSTDOCTORAL RESEARCH SCIENTIST IN STATISTICAL CANCER GENOMICS THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN Grade 7: £29,541 to £33,230p.a.

Applications are invited for a Postdoctoral Research Scientist in Statistical Cancer Genomics to join a newly established research group headed by Dr Christopher Yau based at the Wellcome Trust Centre for Human Genetics (WTCHG). The research will focus on developing statistical methods for the analysis of whole genome cancer sequencing data including modelling tumour heterogeneity and integrative approaches for combining data from multiple sources.

The position would suit a candidate who is interested in developing a career at the interface of Statistics and the Biosciences. Ideally, you will have experience of statistical methods development gained through a PhD (or equivalent) in a quantitative subject (e.g. Mathematics, Statistics, Physics, Engineering or Computer Science). Experience of Bayesian Statistics or machine learning techniques is highly desirable as is evidence of prior experience of developing bioinformatics software and/or analysing genetic data sets.

You will be able to work as part of a team and independently and deliver results to the required standard and schedule. You should also possess the ability to organise and prioritise your own work with minimal supervision and have excellent communication skills, both written and oral. The post will involve interactions with collaborators from Statistics and in Medicine and the Biological Sciences.

The post is fixed-term for two years initially and is available from January 2014 (or as soon as possible thereafter) with the possibility of an extension for a further year. Funding is provided by the Medical Research Council with generous provisions for equipment and travel expenses.

To apply for this role and for further details, including a job description and a person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=110102

Only applications received before 12:00 midday on Monday 2^nd December 2013 will be considered.

Please quote reference 110102 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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