HR

Research Positions

 

 

 

                                                                                                             

UNIVERSITY OF OXFORD                                                                                       POSTDOCTORAL RESEARCH SCIENTIST IN MEMBRANE PROTEIN STRUCTURAL BIOLOGY                                                                                                                          WELLCOME TRUST CENTRE FOR HUMAN GENETICS, DIVISION OF STRUCTURAL BIOLOGY ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                        Grade 7: £30,434- £37,394 p.a. with a discretionary range to £40,847p.a.

Applications are invited for a Postdoctoral Research Scientist in Membrane Protein Structural Biology in the Division of Structural Biology based at the Wellcome Trust Centre for Human Genetics.

You will be based in the research group of Dr. Radu Aricescu and work on the structure/function analysis of a neuronal trans-synaptic protein complex, and gradually make the transition towards the analysis of increasingly larger molecular assemblies built round it.

Facilities available include state of the art infrastructure for automated large-scale cell culture and protein production using mammalian cells, membrane protein purification and biophysical characterization, cryo-electron microscopy/tomography and live-cell fluorescence microscopy. For X-ray crystallography, we have frequent access to Diamond Light Source and other major synchrotrons as required.

You will have a PhD degree in biochemistry or a related field, as well as a demonstrable experience in the expression, purification, crystallization and structure solution of recombinant membrane proteins.You will be able to work as part of a team and also independently and deliver results to required standard and schedule, be able to organize and prioritize own work with minimal supervision and have excellent communication skills, both written and oral.

The post is fixed-term for 2 years in the first instance and funded by the Human Frontiers Research Program.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=115636

Only applications received before 12:00 midday on Thursday, 23rd October 2014 can be considered.

Please quote reference 115636 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD                                                                                       POSTDOCTORAL RESEARCH SCIENTIST IN SYNAPTIC STRUCTURAL BIOLOGY                                                                                                                          WELLCOME TRUST CENTRE FOR HUMAN GENETICS, DIVISION OF STRUCTURAL BIOLOGY ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                         Grade 7: £30,434- £37,394 p.a. with a discretionary range to £40,847p.a.

THIS VACANCY IS FOR INTERNAL APPLICANTS ONLY. Applications are invited for a Postdoctoral Research Scientist in Synaptic Structural Biology in the Division of Structural Biology based at the Wellcome Trust Centre for Human Genetics.

You will be based in the research group of Dr. Radu Aricescu and work on the structure/function analysis of neuronal synaptic receptors. Facilities available include state of the art infrastructure for automated large-scale cell culture and protein production using mammalian cells, membrane protein purification and biophysical characterization, cryo-electron microscopy/tomography and live-cell fluorescence microscopy. For X-ray crystallography, we have frequent access to Diamond Light Source and other major synchrotrons as required.

You will have a PhD degree in biochemistry or a related field, as well as a demonstrable experience in the expression, purification, crystallization and structure solution of recombinant membrane proteins.You will be able to work as part of a team and also independently and deliver results to required standard and schedule, be able to organize and prioritize own work with minimal supervision and have excellent communication skills, both written and oral.

The post is fixed-term for 2 years in the first instance and funded by the Medical Research Council.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=115635

Only applications received before 12:00 midday on Thursday, 23rd October 2014 can be considered.

Please quote reference 115635 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD                                                                                       POSTDOCTORAL RESEARCH SCIENTIST IN TRANSGENIC TECHNOLOGIES                                  WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 7: £30,434 - £37,394 with a discretionary range to £40,847 p.a.

Applications are invited for an enthusiastic Postdoctoral Research Scientist in Transgenic Technologies to help in the day-to-day management of the centre’s transgenic core research group. The group has a service activity, providing genetically modified models to centre groups and has a research activity aimed at establishing and optimizing new technologies for the functional analysis of gene function in vivo.

You will contribute to the all areas of the core and the research activities of the group by providing project management and scientific support in the areas of molecular biology, cell culture, embryo microinjection and cryopreservation. We seek an individual with proven expertise in transgenic technologies and experience in project management who will contribute to the success of the core through supervision of core staff, troubleshooting, hands-on laboratory work and management of projects.

You should have a PhD in molecular biology, biochemistry, genetics, a related discipline or expectation that your thesis will be submitted before December 2014. We anticipate the role to be exceptionally diverse and would suit an individual with a proven track record in work with transgenic models who is enthusiastic and motivated to move to a service oriented role within a core facility. Although service would be the predominant task, there remains considerable flexibility and scope for independent research into genome engineering methodologies.

The position is funded by the Welcome Trust for two years in the first instance with the expectation of continued core funding.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=115395

Only applications received before 12.00 midday on Thursday 6th November 2014 can be considered. Please quote reference 115395 on all correspondence.

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UNIVERSITY OF OXFORD                                                                                                  RESEARCH ASSISTANT IN TRANSGENIC TECHNOLOGIES                                                 WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN                                                                                                                   Grade 6: £27,057 - £32,277 with a discretionary range to £35,256 p.a.

Applications are invited for an enthusiastic Research Assistant in Transgenic Technologies to work in the centre’s transgenic core research group. The group has a service activity, providing genetically modified models to centre groups and has a research activity aimed at establishing and optimizing new technologies for the functional analysis of gene function in vivo.

You will contribute to both the core and the research activities of the group by providing scientific support in the areas of molecular biology, cell culture and histology.  Prior experience in the area of transgenics is desirable but is not essential as full training will be provided. Most importantly, you should have enthusiasm for scientific research, the confidence and ability to acquire the necessary skills in new areas, and the self-motivation to work reliably with a degree of independence after training.

You should also have a good honours degree in Biochemistry, Genetics or a related biological discipline, or alternatively, considerable experience in a transgenics related field 

The position is funded by the Welcome Trust for two years in the first instance with the expectation of continued core funding.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=115394

Only applications received before 12.00 midday on Thursday 6th November 2014 can be considered. Please quote reference 115394 on all correspondence.

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