Research

 

 

 

UNIVERSITY OF OXFORD
LABORATORY TECHNICIAN IN DIL

WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 5: £24,565 - £29,301 with a discretionary range to £32,004 p.a.

THIS IS A READVERTISEMENT, PREVIOUS APPLICANTS NEED NOT APPLY.

Applications are invited for a Laboratory Technician to join the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (DIL) at the Wellcome Trust Centre for Human Genetics.

The DIL aims to treat and prevent the causes of the common autoimmune disease, type 1 diabetes (T1D), in which 50% of cases are diagnosed under age 18 years and consequently run the highest risk of serious complications. This unmet clinical need requires an understanding of the underlying mechanisms of disease.

As a member of the DIL you will have responsibility for the provision of technical and administrative support to ensure the smooth running of the laboratories, to support specific research projects and the Sample Processing Team.

You will have at least A-levels or equivalent qualification in science, together with some relevant experience of working in laboratory environment, including hazardous chemicals.  The ability to manage your own workload and administrative activities is essential.  You will have strong attention to detail required to organise samples and keep meticulous records of sample locations. It is also essential that you have the ability to troubleshoot experiments and write up results. You will have a good knowledge of health and safety regulations in a laboratory environment and experience with LIMs. Your IT skills will include MS Word, Excel and Powerpoint programmes. 

The post is available until 30 September 2020 in the first instance and funded by the JDRF. 

Applications for this vacancy are to be made online. To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/128578-Laboratory-Technician-in-DIL

Only applications received before 12pm, Monday 29 May 2017 can be considered. Please quote reference 128578 on all correspondence.

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UNIVERSITY OF OXFORD
RESEARCH COMPUTING CORE: SYSTEMS ADMINISTRATOR
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 8: £39,324 - £46,924 with a discretionary range to £51,260 p.a.

Applications are invited for a Research Computing Core: Systems Administrator to work in the Wellcome Trust Centre for Human Genetics.

As part of a small team, your main responsibilities will include the day-to-day management and software support for the Research Computing Core’s Linux-based infrastructure including the main 4000+-core compute cluster (currently running SGE); leading the development of a virtualized and containerized compute capability; and management of the Core’s central storage infrastructures that include ~4PB SpectrumScale (GPFS) and ~4PB on diverse NFS servers. You will also help to manage the Research Computing Core network infrastructure that includes both Ethernet and InfiniBand networking.

You will have extensive experience of managing a scientific research computing infrastructure (including server hardware, storage hardware, networking, racking, power and cooling hardware), managing Linux operating systems (installing, updating and tuning) and experience of compiling and analysing scientific software. You will also have experience in designing and deploying one or more of the following emerging trends: virtualization technologies (such as KVM, VMWare ESX or QEMU); cloud computing environments (such as OpenStack or OpenNebula); and containerized environments (such as Docker).

You will have the ability to program in a variety of commonly used programming languages, including scripting languages (primarily Java, perl, python, C++ and shell scripting languages) and to take responsibility for and to manage centralised compute resources on a day-to-day basis. Including troubleshooting of problems with and without support from external specialists.

The position is fixed-term until 30th November 2021 and funded by the Department.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/126748-Research-Computing-Core:-Systems-Administrator

Only applications received before 12.00 midday on Wednesday 31st May 2017 can be considered. Please quote reference 126748 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD
LEAD HIGH THROUGHPUT SEQUENCING BIOINFORMATICIAN 
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN AND NUFFIELD DIVISION OF CLINICAL LABORATORIY SCIENCES, JOHN RADCLIFFE HOSPITAL, HEADINGTON, OXFORD, OX3 9DU

Grade 9: £45,562 - £52,793 with a discretionary range to £57,674 p.a.

Applicants are invited for a Lead High Throughput Sequencing Bioinformatician with the Oxford Biomedical Research Centre’s Genomic Medicine Theme. The Theme undertakes translational genomics research, in particular the clinical application of genomics technologies to rare diseases and cancer. You will be based Wellcome Trust Centre for Human Genetics at the University of Oxford, but will work closely with clinical sequencing groups at the Oxford University Hospital’s Molecular Diagnostics Centre.

You will supervise a team of bioinformaticians and clinical scientists dedicated to analysis of next generation sequencing data (primarily whole genome sequence data).  You will be responsible for developing the analysis pipelines and for designing and implementing novel analytical methods as appropriate, which may involve collaborations with research or commercial partners.  There may also be opportunities for analysis and integration of multi-omics data and immune-oncology applications.  You will supervise members of the clinical and research teams with responsibility for the corresponding analysis, ensuring best practice methods are used and training is provided where necessary and provide an integral link to co-ordinate the work of the research and clinical arms of the Genomic Medicine Theme’s programme, as well as collaborating with clinicians.

You will have the opportunity to conduct an independent research programme that fits with the strategic objectives of the Oxford BRC and takes advantage of the rich research environment at the Wellcome Trust Centre for Human Genetics, for which it is internationally renowned. 

You should have a PhD in bioinformatics or statistical genetics with strong post-doctoral experience in applied DNA sequence analysis, and ideally have held a supervisory and/or developmental role in the past. You will need excellent programming skills in languages such as Perl, C/C++, R, Python, Java, SQL or similar.  The ability to work as part of a team and communicate effectively at all levels is essential. A background in the analysis of next generation sequencing data is highly desirable

The position is fixed-term for 3 years in the first instance and funded by the Oxford Biomedical Research Centre.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/128743-Lead-High-Throughput-Sequencing-Bioinformatician

Only applications received before 12:00 midday on Wednesday 31 May 2017 can be considered.

Please quote reference 128743 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

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UNIVERSITY OF OXFORD
RESEARCH ASSISTANT IN HIGH-THROUGHPUT GENOMICS - MATERNITY COVER 
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 6: £27,629 - £32,958 with a discretionary range to £36,001 p.a.

Applications are invited for a Research Assistant in High-Throughput Genomics – Maternity Coverto work at the Wellcome Trust Centre for Human Genetics.

You will carry out service projects in accordance with Standard Operating Procedures involving sample handling and performing complex experimental procedures using High Throughput Array technologies.

You will undertake genotyping, epigenetic or gene expression projects assigned by array manager as part of the service work and you will provide assistance and troubleshooting to users of the High Throughput Genomics Service within the Centre.

You will have a BSc in Biological Sciences with demonstrable knowledge in molecular biology. You will have experience of performing complex experimental procedures following SOPs, with demonstrable manual dexterity and respect for precision high cost equipment. You will have the ability to organize and prioritize work efficiently, delivering results to a high standard and to an agreed schedule. You will be able to demonstrate a high level of communication skills, both written and oral, and the ability to work effectively within a team.

The position is funded by Genomic Services Income and is fixed-term for 12 months.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/128845-Research-Assistant-in-Hi-Throughput-Genomics-Maternity-Cover

Only applications received before 12.00 midday Wednesday 31st May 2017 can be considered. Please quote reference 128845 on all correspondence.

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UNIVERSITY OF OXFORD
DATA ANALYST TEAM LEADER - DIABETES AND INFLAMMATION LABORATORY
WELLCOME TRUST CENTRE FOR HUMAN GENETICS, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN
Grade 8: £39,324 - £46,924 with a discretionary range to £51,260 p.a.

Applications are invited to join the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory (DIL) at the Wellcome Trust Centre for Human Genetics.

The Diabetes and Inflammation Laboratory (DIL) is at the forefront of experimental medicine approaches to understanding the mechanisms of the common autoimmune disease, type 1 diabetes. We are seeking an motivated individual who, armed with programming and database management skills, is ambitious to help pioneer precision medicine. For candidates with no experience working in biomedical sciences we will provide fast-track training in molecular and early phase clinical trial approaches.

You will be responsible for all aspects of our data, its recovery, storage, usage, sharing, access and archiving. You will lead software development projects that support the DIL and its collaborators, national and international. You will be expected to manage and oversee the informatics requirements of multiple research projects, set the overall software design principle, provide a considerable level of technical expertise to the projects, and will be responsible for selecting solutions and driving them through to practical realisation.

You will hold a Bachelor’s degree (or equivalent) in computer science, have a strong track record of data management and programming in a scientific environment, experience in development, roll-out and support of software systems, extensive experience in object-oriented programming and proficiency in a variety of programming languages, expertise in designing and deploying computing infrastructure which integrates data from heterogeneous database management systems. A PhD in a relevant subject area and experience of line management and financial planning in an IT context will be an advantage.

The post is available until 30 September 2020 in the first instance and is funded by the Wellcome Trust.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

To apply for this role and for further details, including a job description and person specification, please click on the link below:

http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/128787-Data-Analyst-Team-Leader-Diabetes-and-Inflammation-Laboratory

Only applications received before 12pm, Monday, 12th June 2017 can be considered. Please quote reference 128787 on all correspondence. Interviews will take place on 29 and 30 June 2017.