UNIVERSITY OF OXFORD
POSTDOCTORAL RESEARCH ASSOCIATE IN ELECTRON CRYO-TOMOGRAPHY
THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS, DIVISION OF STRUCTURAL BIOLOGY, OXFORD PARTICLE IMAGING CENTRE, ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN.
Grade 7: £29,249 - £35,938p.a. with a discretionary range to £39,257p.a.
Applications are invited for a Postdoctoral Research Associate in Electron Cryo-tomography to join Dr. Juha Huiskonen’s research group at the Oxford Particle Imaging Centre, located at the Division of Structural Biology, University of Oxford. The major goal of the group is to elucidate structures and host cell interactions of hemorrhagic fever causing zoonotic viruses, using structural biology, molecular biology, and biophysical methods.
Your will have experience to perform electron cryo-microscopy and tomography studies of purified viruses, virus-like particles and virus-infected cells including experience in Unix operating system which includes computational data analysis such as tomographic reconstruction with contrast transfer function correction, in addition to tomographic sub-volume alignment, classification, and averaging. Your secondary roles will be to evaluate and further develop computational tools for tomographic processing and to co-supervise post-graduate students.
A successful applicant will have completed a PhD in biochemistry, molecular biology, or biophysics and have strong background in electron cryo-microscopy, tomography, image processing and/or scientific programming.
Oxford Particle Imaging Centre offers an FEI F30 ‘Polara’ electron microscope in a biosafety laboratory. The microscope is equipped with a GIF Quantum post-column energy filter making it ideal for electron cryo-tomography. We also benefit from the wide structural biology community in the Division and have close links to the Oxford Protein Production Facility UK and Diamond Light Source.
The position is funded by the Medical Research Council and is fixed term until 30th June 2015 in the first instance.
To apply for this role and for further details, including a job description and a person specification, please click on the link below:
https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=103020
Only applications received before 12.00 midday on Thursday 14th June 2012 will be considered.
Please quote reference 103020 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.
UNIVERSITY OF OXFORD
RESEARCH ASSISTANT
THE WELLCOME TRUST CENTRE FOR HUMAN GENETICS, DIVISION OF STRUCTURAL BIOLOGY
ROOSEVELT DRIVE, HEADINGTON, OXFORD, OX3 7BN.
Grade 6: £26,004 - £31,020p.a. with a discretionary range to £33,884p.a.
Applications are invited for a Research Assistant to be based at the Division of Structural Biology
You will be required to support the work of the Karlin research group by providing technical assistance in the expression and purification of proteins for structural analysis. Our aim is to solve the 3D structure of several viral proteins generated de novo (e.g. not by duplication), expected to have a completely new fold. The post would involve expression and purification of proteins but also designing and cloning new constructs to take the project in novel directions.
You will have a BSc degree in biology, biochemistry or molecular biology and significant experience of protein expression and structural biology. You should master common molecular biology techniques (cloning, etc.) and protein expression (in bacteria and mammalian cells), purification and characterization.
The position is funded by the Wellcome Trust and is fixed term for 6 months in the first instance. We are looking for someone to start as soon as possible.
To apply for this role and for further details, including a job description and a person specification, please click on the link below:
https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=103017
Only applications received before 12.00 midday on Thursday 14th June 2012 will be considered.
Please quote reference 103017 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.
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