Reedik Mägi

Senior Statistical Geneticist

Reedik_standardResearch summary

My main interest is in implementing current statistical methods to computer software and developing new methods for association mapping. I am currently involved in several meta-analyses of various genome-wide association studies. I am also interested in studying homozygous regions of Human genome, CNVs and in application of these methods in association analyses. I have worked on several studies concerning linkage disequilibrium mapping of populations, population structure, marker selection and haplotype analysis. I am particularly interested in tagging SNP selection for association analysis and transferability of these tagging SNPs among populations.

Publication List

Krjutskov, K.; Andreson, R.; Mägi, R.; Nikopensius, T.; Khrunin, A.; Mihailov, E.; Tammekivi, V.; Sork, H.; Remm, M.; Metspalu, A. (2008). Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays. Nucleic Acids Research, 36(12), e75. PMID: 18539607

Tamm, R.; Oselin, K.; Kallassalu, K.; Mägi, R.; Anier, K.; Remm, M.; Metspalu, A. (2008). Thiopurine S-methyltransferase (TPMT) pharmacogenetics: three new mutations and haplotype analysis in the Estonian population. Clinical Chemistry and Laboratory Medicine, 46(7), 974 - 979. PMID: 18605963

Mägi, R.; Pfeufer, A.; Nelis, M.; Montpetit, A.; Metspalu, A.; Remm, M. (2007). Evaluating the performance of commercial whole-genome marker sets for capturing common genetic variation. BMC Genomics, 8(159), x. PMID: 17562002

Kuningas, M.; Mägi, R.; Westendorp, R.G.; Slagboom, P.E.; Remm, M.; van Heemst, D. (2007). Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age. European Journal of Human Genetics, 15(3), 294 - 301. PMID: 17245409

Montpetit, A.; Nelis, M.; Laflamme, P.; Mägi, R.; Ke, X.Y.; Remm, M.; Cardon, L.; Hudson, T.J.; Metspalu, A. (2006). An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population . PLOS GENETICS, 2(3), 282 - 290. PMID: 16532062

Mägi, R.; Kaplinski, L.; Remm, M. (2006). The Whole Genome TagSNP Selection and Transferability Among HapMap Populations. In: Pacific Symposium on Biocomputing 2006: 2006. World Scientific Publ Co Pte Ltd, 2006, 535 - 543. PMID: 17094267

Mueller, J. C.; Lõhmussaar, E.; Mägi, R.; Remm, M.; Bettecken, T.; Lichtner, P.; Huber, S.; Illig, T; Luedemann, J.; Schreiber, S.; Wichmann, H. E.; Pramstaller, P.; Romeo, G.; Testa, A.; Metspalu, A.; Meitinger, T. (2005). Linkage Disequilibrium Patterns and tagSNP Transferability among European Populations. American Journal of Human Genetics, 76(3), 387 - 398. PMID: 15637659

Dawson, E.; Abecasis, GR.; Bumpstead, S.; Chen, Y.; Hunt, S.; Beare, DM.; Pabial, J.; Dibling, T.; Tinsley, E.; Kirby, S.; Carter, D.; Papaspyridonos, M.; Livingstone, S.; Ganske, R.; Lohmmussaar, E.; Zernant, J.; Tonisson, N.; Remm, M.; Mägi, R.; Puurand, T.; Vilo, J.; Kurg, A.; Rice, K.; Deloukas, P.; Mott, R.; Metspalu, A.; Bentley, D.R.; Cardon, L.R.; Dunham, I. (2002). A first-generation linkage disequilibrium map of human chromosome 22. Nature, 418(6897), 544 - 548. PMID: 12110843

Research Areas

Statistical genetics and population genetics


Association analysis, population genetics

Contact Details

Wellcome Trust Centre for Human Genetics
University of Oxford
Roosevelt Drive
Oxford; OX3 7BN; UK


tel: +44 (0)1865 287829

fax: +44 (0)1865 287664