Selected recent publications

Vannberg FO, Chapman SJ, Hill AV. Human genetic susceptibility to intracellular pathogens. Immunol Rev. 2011 Mar;240(1):105-16. doi: 10.1111/j.1600-065X.2010.00996.x. PMID: 21349089

Chapman SJ, Khor CC, Vannberg FO, Rautanen A, Walley A, Segal S, Moore CE, Davies RJ, Day NP, Peshu N, Crook DW, Berkley JA, Williams TN, Scott JA, Hill AV. Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. Crit Care. 2010;14(6):R227. Epub 2010 Dec 20. PMID:21171993

Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium, Morris AP, Meyer CG, Horstmann RD, Hill AV. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat Genet. 2010 Sep;42(9):739-41. Epub 2010 Aug 8.PMID:20694014

Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, Chopra R, Reddy BS, Garg VK, Roy S, Meisner S, Hazra SK, Saha B, Floyd S, Keating BJ, Kim C, Fairfax BP, Knight JC, Hill PC, Adegbola RA, Hakonarson H, Fine PE, Pitchappan RM, Bamezai RN, Hill AV, Vannberg FO. Leprosy and the adaptation of human toll-like receptor 1. PLoS Pathog. 2010 Jul 1;6:e1000979. PMID: 20617178

Khor CC, Vannberg FO, Chapman SJ, Guo H, Wong SH, Walley AJ, Vukcevic D, Rautanen A, Mills TC, Chang KC, Kam KM, Crampin AC, Ngwira B, Leung CC, Tam CM, Chan CY, Sung JJ, Yew WW, Toh KY, Tay SK, Kwiatkowski D, Lienhardt C, Hien TT, Day NP, Peshu N, Marsh K, Maitland K, Scott JA, Williams TN, Berkley JA, Floyd S, Tang NL, Fine PE, Goh DL, Hill AV. CISH and susceptibility to infectious diseases. N Engl J Med. 2010 Jun 3;362(22):2092-101. Epub 2010 May 19. PMID:20484391

Wong SH, Hill AV, Vannberg FO; India-Africa-United Kingdom Leprosy Genetics Consortium. Genomewide association study of leprosy. N Engl J Med. 2010 Apr 15;362(15):1446-7; author reply 1447-8. PMID: 20393182

Chapman SJ, Vannberg FO, Khor CC, Rautanen A, Maskell NA, Davies CW, Moore CE, Day NP, Crook DW, Davies RJ, Hill AV. Mannose-binding lectin genotypes: lack of association with susceptibility to thoracic empyema. BMC Med Genet. 2010 Jan 15;11:5.PMID: 20078874

Lyons EJ, Amos W, Berkley JA, Mwangi I, Shafi M, Williams TN, Newton CR, Peshu N, Marsh K, Scott JA, Hill AV. Homozygosity and risk of childhood death due to invasive bacterial disease. BMC Med Genet. 2009 Jun 12;10:55.PMID:19523202   

Chapman SJ, Khor CC, Vannberg FO, Rautanen A, Segal S, Moore CE, Davies RJ, Day NP, Peshu N, Crook DW, Berkley JA, Williams TN, Scott JA, Hill AV. NFKBIZ polymorphisms and susceptibility to pneumococcal disease in European and African populations. Genes Immun. 2010 Jun;11(4):319-25. Epub 2009 Oct 1. PMID: 19798075

Vannberg FO, Chapman SJ, Khor CC, Tosh K, Floyd S, Jackson-Sillah D, Crampin A, Sichali L, Bah B, Gustafson P, Aaby P, McAdam KP, Bah-Sow O, Lienhardt C,Sirugo G, Fine P, Hill AV. CD209 genetic polymorphism and tuberculosis disease.PLoS ONE. 2008 Jan 2;3(1):e1388.PMID: 18167547 

Hennig BJ, Fielding K, Broxholme J, Diatta M, Mendy M, Moore C, Pollard AJ,Rayco-Solon P, Sirugo G, van der Sande MA, Waight P, Whittle HC, Zaman SM, Hill AV, Hall AJ. Host genetic factors and vaccine-induced immunity to hepatitis B virus infection.PLoS ONE. 2008 Mar 26;3(3):e1898.PMID: 18365030

Cooke GS, Campbell SJ, Bennett S, Lienhardt C, McAdam KP, Sirugo G, Sow O,Gustafson P, Mwangulu F, van Helden P, Fine P, Hoal EG, Hill AV. Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ inhuman tuberculosis. Am J Respir Crit Care Med. 2008 Jul 15;178(2):203-7. Epub 2008 Apr 17.PMID: 18420963

Khor CC, Vannberg FO, Chapman SJ, Walley A, Aucan C, Loke H, White NJ, Peto T,Khor LK, Kwiatkowski D, Day N, Scott A, Berkley JA, Marsh K, Peshu N, Maitland K,Williams TN, Hill AV. Positive replication and linkage disequilibrium mapping of the chromosome 21q22.1 malaria susceptibility locus. Genes Immun. 2007 Oct;8(7):570-6. Epub 2007 Aug 16.PMID: 17703179

Chapman SJ, Khor CC, Vannberg FO, Frodsham A, Walley A, Maskell NA, Davies CW, Segal S, Moore CE, Gillespie SH, Denny P, Day NP, Crook DW, Davies RJ, Hill AV. IkappaB genetic polymorphisms and invasive pneumococcal disease. Am J Respir Crit Care Med. 2007 Jul 15;176(2):181-7. Epub 2007 Apr 26. PMID: 17463416

Khor CC, Chapman SJ, Vannberg FO, Dunne A, Murphy C, Ling EY, Frodsham AJ, Walley AJ, Kyrieleis O, Khan A, Aucan C, Segal S, Moore CE, Knox K, Campbell SJ, Lienhardt C, Scott A, Aaby P, Sow OY, Grignani RT, Sillah J, Sirugo G, Peshu N, Williams TN, Maitland K, Davies RJ, Kwiatkowski DP, Day NP, Yala D, Crook DW, Marsh K, Berkley JA, O'Neill LA, Hill AV. A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet. 2007 Apr;39(4):523-8. Epub 2007 Feb 25. PMID: 17322885

Chapman SJ, Khor CC, Vannberg FO, Maskell NA, Davies CW, Hedley EL, Segal S, Moore CE, Knox K, Day NP, Gillespie SH, Crook DW, Davies RJ, Hill AV. PTPN22 and invasive bacterial disease. Nat Genet. 2006 May;38(5):499-500. PMID: 16642008

Roy S Knox K, Segal S, Griffiths D, Moore CE, Welsh KI, Smarason A, Day NP, McPheat WL, Crook DW, Hill AV, and the Oxford Pneumococcal Surveillance Group. MBL genotype and risk of invasive pneumococcal disease: a case-control study. Lancet 2002; 359: 1569-73. PMID: 12047967

Roy S, Knox K, Griffiths D, Crook D, Hill AVS. C reactive protein polymorphism is associated with susceptibility to invasive pneumococcal disease. BMJ 2002; 324: 1369. PMID: 12052806