Fisher Group - Molecular Neuroscience
Selected publications from the past five years:
2009
Newbury DF, Winchester L, Addis L, Paracchini S, Buckingham LL, Clark A, Cohen W, Cowie H, Dworzynski K, Everitt A, Goodyer IM, Hennessy E, Kindley AD, Miller LL, Nasir J, O'Hare A, Shaw D, Simkin Z, Simonoff E, Slonims V, Watson J, Ragoussis J, Fisher SE, Seckl JR, Helms PJ, Bolton PF, Pickles A, Conti-Ramsden G, Baird G, Bishop DV, Monaco AP (2009) CMIP and ATP2C2 Modulate Phonological Short-Term Memory in Language Impairment. Am. J. Hum. Genet. Jul 29. [Epub ahead of print]; PMID: 19646677
Kurt S, Groszer M, Fisher SE, Ehret G (2009) Modified sound-evoked brainstem potentials in Foxp2 mutant mice. Brain Res. Jul 9. [Epub ahead of print]; PMID: 19596273
Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, Somel M, Brückner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Müller U, Groszer M, Adler T, Aguilar A, Bolle I, Calzada-Wack J, Claudia C, Ehrhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Hölzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Moßbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Zimmer A, Fisher SE, Morgenstern R, Arendt T, Hrabé de Angelis M, Fischer J, Schwarz J, Pääbo S (2009) A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell 137: 961-71; PMID: 19490899
Vernes SC, MacDermot KD, Monaco AP, Fisher SE (2009) Assessing the impact of FOXP1 mutations on developmental verbal dyspraxia. Eur. J. Hum. Genet. Apr 8. [Epub ahead of print]; PMID: 19352412
Fisher SE, Scharff C (2009) FOXP2 as a molecular window into speech and language. Trends Genet. 25:166-77 (refereed review article); PMID: 19304338
2008
Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcón M, Oliver PL, Davies KE, Geschwind DH, Monaco AP, Fisher SE (2008) A functional genetic link between distinct developmental language disorders. N. Engl. J. Med. 359: 2337-2345; PMID: 18987363
Groszer M, Keays DA, Deacon RMJ, de Bono JP, Prasad-Mulcare S, Gaub S, Baum MG, French CA, Nicod J, Coventry JA, Enard W, Fray M, Brown SDM, Nolan PM, Pääbo S, Channon KM, Costa RM, Eilers J, Ehret G, Rawlins JNP, Fisher SE (2008) Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Curr. Biol. 18: 354-362; PMID: 18328704
2007
Spiteri E, Konopka G, Coppola G, Bomar J, Oldham M, Ou J, Vernes SC, Fisher SE, Ren B, Geschwind DH (2007) Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am. J. Hum. Genet. 81: 1144-57; PMID: 17999357
Vernes SC, Spiteri E, Nicod J, Groszer M, Taylor JM, Davies KE, Geschwind DH, Fisher SE (2007) High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders. Am. J. Hum. Genet. 81: 1232-50; PMID: 17999362
French CA, Groszer M, Preece C, Coupe A-M, Rajewsky K, Fisher SE (2007) Generation of mice with a conditional Foxp2 null allele. Genesis 45: 440-6; PMID: 17619227
Fisher SE (2007) Molecular windows into speech and language disorders. Folia Phoniatr. Logop. 59: 130-40; PMID: 17556856
2006
White SA, Fisher SE, Geschwind DH, Scharff C, Holy TE (2006) Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language. J. Neurosci. 26: 10376-9; PMID: 17035521
Vernes SC, Nicod J, Elahi FM, Coventry JA, Kenny N, Coupe A-M, Bird LE, Davies KE, Fisher SE (2006) Functional genetic analysis of mutations implicated in a human speech and language disorder. Hum. Mol. Genet. 15: 3154-67; PMID: 16984964
Fisher SE (2006) Tangled webs: tracing the connections between genes and cognition. Cognition 101: 270-97 (refereed review article); PMID: 16764847
Fisher SE, Marcus GF (2006) The eloquent ape: genes, brains and the evolution of language. Nature Rev. Genet. 7: 9-20 (refereed review article); PMID: 16369568
2005
MacDermot KD, Bonora E, Sykes N, Coupe A-M, Lai CSL, Vernes SC, Vargha-Khadem F, McKenzie F, Smith RL, Monaco AP, Fisher SE (2005) Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits. Am. J. Hum. Genet. 76: 1074-1080; PMID: 15877281