Publications

2015

Rahmioglu N, Montgomery GW, Zondervan KT. Genetics of Endometriosis. Womens Health. 2015. [Epub ahead of print] PMID: 26441051

Lu Y, Cuellar-Partida G, Painter JN, Nyholt DR; Australian Ovarian Cancer Study; International Endogene Consortium (IEC), Morris AP, Fasching PA, Hein A, Burghaus S, Beckmann MW, Lambrechts D, Van Nieuwenhuysen E, Vergote I, Vanderstichele A, Doherty JA, Rossing MA, Wicklund KG, Chang-Claude J, Eilber U, Rudolph A, Wang-Gohrke S, Goodman MT, Bogdanova N, Dörk T, Dürst M, Hillemanns P, Runnebaum IB, Antonenkova N, Butzow R, Leminen A, Nevanlinna H, Pelttari LM, Edwards RP, Kelley JL, Modugno F, Moysich KB, Ness RB, Cannioto R, Høgdall E, Jensen A, Giles GG, Bruinsma F, Kjaer SK, Hildebrandt MA, Liang D, Lu KH, Wu X, Bisogna M, Dao F, Levine DA, Cramer DW, Terry KL, Tworoger SS, Missmer S, Bjorge L, Salvesen HB, Kopperud RK, Bischof K, Aben KK, Kiemeney LA, Massuger LF, Brooks-Wilson A, Olson SH, McGuire V, Rothstein JH, Sieh W, Whittemore AS, Cook LS, Le ND, Gilks CB, Gronwald J, Jakubowska A, Lubiński J, Gawełko J, Song H, Tyrer JP, Wentzensen N, Brinton L, Trabert B, Lissowska J, Mclaughlin JR, Narod SA, Phelan C, Anton-Culver H, Ziogas A, Eccles D, Gayther SA, Gentry-Maharaj A, Menon U, Ramus SJ, Wu AH, Dansonka-Mieszkowska A, Kupryjanczyk J, Timorek A, Szafron L, Cunningham JM, Fridley BL, Winham SJ, Bandera EV, Poole EM, Morgan TK, Risch HA, Goode EL, Schildkraut JM, Webb PM, Pearce CL, Berchuck A, Pharoah PD, Montgomery GW, Zondervan KT, Chenevix-Trench G, MacGregor S. Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. Hum Mol Genet. 2015;24(20):5955-64. PMID: 26231222

Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard J, Tandre K, Hedman ÅK, Kwan T, Ge B; Multiple Tissue Human Expression Resource Consortium, Rönnblom L, McCarthy MI, Deloukas P, Richmond T, Burgess D, Spector TD, Tchernof A, Marceau S, Lathrop M, Vohl MC, Pastinen T, Grundberg E. Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants. Nat Commun. 2015;6:7211.PMID: 26021296

Fawole AO, Bello FA, Ogunbode O, Odukogbe AT, Nkwocha GC, Nnoaham KE, Zondervan KT, Akintan A, Abdus-Salam RA, Okunlola MA. Endometriosis and associated symptoms among Nigerian women. Int J Gynaecol Obstet. 2015 Aug;130(2):190-4. PMID: 25935474

Sapkota Y, Attia J, Gordon SD, Henders AK, Holliday EG, Rahmioglu N, MacGregor S, Martin NG, McEvoy M, Morris AP, Scott RJ, Zondervan KT, Montgomery GW, Nyholt DR. Genetic burden associated with varying degrees of disease severity in endometriosis. Mol Hum Reprod. 2015 Jul;21(7):594-602.PMID: 25882541

Rahmioglu N, Macgregor S, Drong AW, Hedman AK, Harris HR, Randall JC, Prokopenko I, The International EndoGene Consortium (IEC), The GIANT Consortium, Nyholt DR, Morris AP, Montgomery GW, Missmer SA, Lindgren CM, Zondervan KT. Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum Mol Genet 2015;24(4):1185-99.PMID: 2529617

Sapkota Y, Low SK, Attia J, Gordon SD, Henders AK, Holliday EG, MacGregor S, Martin NG, McEvoy M, Morris AP, Takahashi A, Scott RJ, Kubo M, Zondervan KT, Montgomery GW, Nyholt DR. Association between endometriosis and the interleukin 1A (IL1A) locus. Hum Reprod 2015;30(1):239-48. PMID: 25336714

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, et al [400+ authors]. New genetic loci link adipose and insulin biology to body fat distribution. Nature 2015 Feb 12;518:187-96. PMID: 25673412.

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C., et al. [400+ authors]. Genetic studies of body mass index yield new insights for obesity biology. Nature 2015;518:197-206. PMID: 25673413

2014

Fassbender A, Rahmioglu N, Vitonis AF, Vigano P, Giudice LC, D'Hooghe TM, Hummelshoj L, Adamson GD, [Becker CM*, Missmer SA*, Zondervan KT*] for the WERF EPHect Working Group. WERF Endometriosis Phenome and Biobanking Harmonization Project (EPHect): IV. Tissue collection, processing and storage in endometriosis research. Fertil Steril 2014;102(5):1244-53. PMID:25256928.

Rahmioglu N, Fassbender A, Vitonis AF, Tworoger S, Hummelshoj L, D’Hooghe TM, Adamson GD, Giudice LC, [Becker CM, Zondervan KT*, Missmer SA*] for the WERF EPHect Working Group. WERF Endometriosis Phenome and Biobanking Harmonization Project (EPHect): III. Fluid biospecimen collection, processing and storage in endometriosis research. Fertil Steril 2014;102(5):1233-43. PMID:25256929


Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice LC, Stratton P, Adamson GD, Becker CM, [Zondervan KT*, Missmer SA*] for the WERF EPHect Working GroupWERF Endometriosis Phenome and Biobanking Harmonization Project (EPHect): II. Clinical and covariate phenotype data collection in endometriosis research. Fertil Steril 2014;102(5):1223-32. PMID:25256930

Becker CM, Laufer MR, Stratton P, Hummelshoj L, Missmer SA, Zondervan KT, Adamson GD, for the WERF EPHect Working Group. WERF Endometriosis Phenome and Biobanking Harmonization Project (EPHect): I. Surgical phenotype data collection in endometriosis research. Fertil Steril 2014;102(5):1213-22. PMID:25150390

Pinnick KE, Nicholson G, Manolopoulos KN, McQuaid SE, Valet P, Frayn KN, Denton N, Min JL, Zondervan KT, Fleckner J; The MolPAGE consortium, McCarthy MI, Holmes CC, Karpe F. Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications. Diabetes 2014;63:3785-97. PMID:24947352

Rahmioglu N, Nyholt DR, Morris AP, Missmer SA, Montgomery GW, Zondervan KT. Genetic variants underlying endometriosis risk: insights from eight genome-wide association and replication datasets in 11,000 cases and 32,000 controls. Hum Reprod Update 2014; 20:702-16. PMID: 24676469

Brawn J, Morotti M, Zondervan KT, Becker CM, Vincent K. Central changes associated with chronic pelvic pain and endometriosis. Hum Reprod Update 2014; 20(5):737-47. PMID:24920437

Morotti M, Vincent K, Brawn J, Zondervan KT, Becker CM. Peripheral changes in endometriosis-associated pain. Hum Reprod Update 2014; 20:717-36. PMID:24859987

Painter JN, Nyholt DR, Krause L, Zhao ZZ, Chapman B, Zhang C, Medland S, Martin NG, Kennedy S, Treloar S, Zondervan K, Montgomery GW. Common variants in the CYP2C19 gene are associated with susceptibility to endometriosis. Fertil Steril. 2014; 102:496-502. PMID:24796765

The MuTHER Consortium. Differential methylation of the TRPA1 promoter in pain sensitivity. Nat Comm 2014; 4;5:2978.PMID:24496475

Montgomery GW, Zondervan KT, Nyholt DR. The future for genetic studies in reproduction. Mol Hum Reprod. 2014;20:1-14. PMID:23982303

2013

Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S, Rees SD, Ng DP, Wong TY, Yamauchi T, Hara K, Tanaka Y, Hirose H, McCarthy MI, Morris AP; DIAGRAM; MuTHER Consortium; AGEN, Basit A, Barnett AH, Katulanda P, Matthews D, Mohan V, Wander GS, Singh JR, Mehra NK, Ralhan S, Kamboh MI, Mulvihill JJ, Maegawa H, Tobe K, Maeda S, Cho YS, Tai ES, Kelly MA, Chambers JC, Kooner JS, Kadowaki T, Deloukas P, Rader DJ, Danesh J, Sanghera DK. Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. Diabetes 2013;62:1746-55. PMID: 23300278

Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, Busche S, Yuan W, Nisbet J, Sekowska M, Wilk A, Barrett A, Small KS, Ge B, Caron M, Shin SY; MuTHER Consortium, Lathrop M, Dermitzakis ET, McCarthy MI, Spector TD, Bell JT, Deloukas P. Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet 2013;93:876-90. PMID: 24183450

Lee SH, Harold D, Nyholt DR; ANZGene Consortium; ENDOGENE Consortium; the Genetic and Environmental Risk for Alzheimer’s disease (GERAD1) Consortium, Goddard ME, Zondervan KT, Williams J, Montgomery GW, Wray NR, Visscher PM. Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. Hum Mol Genet 2013;22:832-41. PMID:23193196

2012

Nyholt DR, Low SK, Anderson CA, Painter JN, Uno S, Morris AP, MacGregor S, Gordon SD, Henders AK, Martin NG, Attia J, Holliday EG, McEvoy M, Scott RJ, Kennedy SH, Treloar SA, Missmer SA, Adachi S,  Tanaka K, Nakamura Y, Zondervan KT*, Zembutsu H, Montgomery GW. Genome-wide association meta-analysis identifies new endometriosis risk loci. Nat Genet 2012;44:1355-9.Luong HTT, Nyholt DR, Painter JN, Kennedy S, Treloar SA, [Zondervan KT, Montgomery GW]. No evidence to support a role for common KRAS variants, including the let-7 microRNA binding site, in risk of endometriosis. Human Reprod 2012;27:3616-21. PMID:23104006

Eggert SL, Huyck KL, Somasundaram P, Kavalla R, Stewart EA, Lu AT, Painter JN, Montgomery GW, Medland SE, Nyholt DR, Treloar SA, Zondervan KT, Heath AC, Madden PAF, Rose L, Ridker PM, Chasman DI, Martin NG, Cantor RM, Morton CC. Genome-wide linkage and association analyses in uterine leiomyomata reveal FASN as a risk gene. AJHG 2012; 91:621-8.PMID:23040493

Luong HTT, Nyholt DR, Painter JN, Kennedy S, Treloar SA, [Zondervan KT, Montgomery GW]. No evidence to support a role for common KRAS variants, including the let-7 microRNA binding site, in risk of endometriosis. Human Reprod 2012;27:3616-21.PMID:23010532

Grundberg E, Small KS, Hedman AK, Nica AC, Buil A, Keildson S, Bell JT, Yang T-P, Barrett A, Nisbet J,  Sekowska M, Wilk A,  Shin S-Y, Glass D, Travers M,  Min JL, Ring S, Ho K, Thorleifsson G, Kong A, Thorsteindottir U, Ainali BC, Dimas AS, Hassanali N, Ingle C, Knowles D, Krestyaninova M, Lowe CE, Meduri E, Di Meglio P,  Montgomery SB, Parts L, Potter S, Surdulescu G, Tsaprouni L, Tsoka S, Bataille V, Durbin R, Nestle FO, O’Rahilly S, Soranzo N, Lindgren SM, Zondervan KT, Ahmadi K, Schadt EE, Stefansson K, Davey Smith G, McCarthy MI, Deloukas P, Dermitzakis ET, Spector TD, for the MuTHER consortium. Mapping cis and trans regulatory effects across multiple tissues in twins: the MuTHER Study. Nat Genet 2012;44:1084-1089. PMID:22941192

Rahmioglu N, Missmer SA, Montgomery GW, Zondervan KT. Insights into Assessing the Genetics of Endometriosis in Humans and in Macaques. Curr Obstet Gynecol Rep 2012 Sep;1(3):124-137. PMID:22924156

Nnoaham KE, Kumbang J, Kennedy SH, Webster P, Zondervan KT. Is early age at menarche a risk factor for endometriosis? A systematic review and meta-analysis of case-control studies. Fert Steril, 2012 ;98: 702-12.PMID:22728052

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population. Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A, Shin SY, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica A, Small KS, The MuTHER Consortium, Dermitzakis ET, McCarthy MI, Mill J, Spector TD, Deloukas P. PLoS Genet. 2012;8:e1002629.PMID:22532803

Nnoaham KE, Hummelshoj L, Kennedy SH, Jenkinson C, Zondervan KT, for the WERF WHSS Consortium. Developing symptom-based predictive models of endometriosis as a clinical screening tool: results from a multi-centre study. Fert Steril, 2012;98:692-701.PMID:22657249

Min JL, Nicholson G, Halgrimsdottir I, Almstrup K, Petri A, Barrett A, Travers M, Rayner NW, Mägi R, Pettersson FH, Broxholme J, Neville MJ, Wills QF, Cheeseman J; The GIANT Consortium; The MolPAGE Consortium, Allen M, Holmes CC, Spector TD, Fleckner J, McCarthy MI, Karpe F, Lindgren CM, Zondervan KT. Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes. PLoS Genet. 2012;8:e1002505.PMID:22383892

2011

Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman ÅK, Morris AP, McCarthy MI; DIAGRAM Consortium; MuTHER Consortium, Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M.  Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet. 2011 Dec 11;44(1):67-72. doi: 10.1038/ng.1019.  PMID: 22158537.

Dancet EA, Ameye L, Sermeus W, Welkenhuysen M, Nelen WL, Tully L, De Bie B, Veit J, Vedsted-Hansen H, Zondervan KT, De Cicco C, Kremer JA, Timmerman D, D'Hooghe TM.  The ENDOCARE questionnaire (ECQ): a valid and reliable instrument to measure the patient-centeredness of endometriosis care in Europe.  Hum Reprod. 2011 Nov;26(11):2988-99. Epub 2011 Sep 6. PMID:21896549.

Rantalainen M, Herrera BM, Nicholson G, Bowden R, Wills QF, Min JL, Neville MJ, Barrett A, Allen M, Rayner NW, Fleckner J, McCarthy MI, Zondervan KT, Karpe F, Holmes CC, Lindgren CM. MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven. PLoS One. 2011;6(11):e27338. Epub 2011 Nov 15. PMID: 22102887.

Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJ, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJ, Luan J, Makrilakis K, Manning AK, Martínez-Larrad MT, Narisu N, Nastase Mannila M, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancáková A, Stirrups K, Swift AJ, Syvänen AC, Tuomi T, van 't Hooft FM, Walker M, Weedon MN, Xie W, Zethelius B; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium, Ongen H, Mälarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Ríos M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC.  Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.  Diabetes. 2011 Oct;60(10):2624-34. Epub 2011 Aug 26.  PMID: 21873549

Lin J, Zong L, Kennedy SH, Zondervan KT. Coding regions of INHBA, SFRP4 and HOXA10 are not implicated in familial endometriosis linked to chromosome 7p13-15. Mol Hum Reprod. 2011 Oct;17(10):605-11. doi: 10.1093/molehr/gar035. Epub 2011 May 16. PMID: 21576276.

Nicholson G, Rantalainen M, Li JV, Maher AD, Malmodin D, Ahmadi KR, Faber JH, Barrett A, Min JL, Rayner NW, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U; MolPAGE Consortium, Donnelly P, Illig T, Adamski J, Suhre K, Allen M, Zondervan KT, Spector TD, Nicholson JK, Lindon JC, Baunsgaard D, Holmes E, McCarthy MI, Holmes CC.  A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.  PLoS Genet. 2011 Sep;7(9):e1002270. Epub 2011 Sep 8.  PMID: 21931564.

Nicholson G, Rantalainen M, Maher AD, Li JV, Malmodin D, Ahmadi KR, Faber JH, Hallgrímsdóttir IB, Barrett A, Toft H, Krestyaninova M, Viksna J, Neogi SG, Dumas ME, Sarkans U, The Molpage Consortium, Silverman BW, Donnelly P, Nicholson JK, Allen M, Zondervan KT, Lindon JC, Spector TD, McCarthy MI, Holmes E, Baunsgaard D, Holmes CC. Human metabolic profiles are stably controlled by genetic and environmental variation.  Mol Syst Biol. 2011 Aug 30;7:525. doi: 10.1038/msb.2011.57.  PMID: 21878913

Kooner JS, Saleheen D, Sim X, Sehmi J, Zhang W, Frossard P, Been LF, Chia KS, Dimas AS, Hassanali N, Jafar T, Jowett JB, Li X, Radha V, Rees SD, Takeuchi F, Young R, Aung T, Basit A, Chidambaram M, Das D, Grundberg E, Hedman AK, Hydrie ZI, Islam M, Khor CC, Kowlessur S, Kristensen MM, Liju S, Lim WY, Matthews DR, Liu J, Morris AP, Nica AC, Pinidiyapathirage JM, Prokopenko I, Rasheed A, Samuel M, Shah N, Shera AS, Small KS, Suo C, Wickremasinghe AR, Wong TY, Yang M, Zhang F; DIAGRAM; MuTHER, Abecasis GR, Barnett AH, Caulfield M, Deloukas P, Frayling TM, Froguel P, Kato N, Katulanda P, Kelly MA, Liang J, Mohan V, Sanghera DK, Scott J, Seielstad M, Zimmet PZ, Elliott P, Teo YY, McCarthy MI, Danesh J, Tai ES, Chambers JC.Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.  Nat Genet. 2011 Aug 28;43(10):984-9. doi: 10.1038/ng.921. PMID: 21874001.

Nnoaham KE, Hummelshoj L, Webster P, d'Hooghe T, de Cicco Nardone F, de Cicco Nardone C, Jenkinson C, Kennedy SH, Zondervan KT; World Endometriosis Research Foundation Global Study of Women's Health consortium. Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries. Fertil Steril. 2011 Aug;96(2):366-373.e8. Epub 2011 Jun 30. PMID: 21718982.

Min JL, Taylor JM, Richards JB, Watts T, Pettersson FH, Broxholme J, Ahmadi KR, Surdulescu GL, Lowy E, Gieger C, Newton-Cheh C, Perola M, Soranzo N, Surakka I, Lindgren CM, Ragoussis J, Morris AP, Cardon LR, Spector TD, Zondervan KT. The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS One. 2011;6(7):e22070. Epub 2011 Jul 15. PMID: 21789213.

Painter JN, Nyholt DR, Morris A, Zhao ZZ, Henders AK, Lambert A, Wallace L, Martin NG, Kennedy SH, Treloar SA, Zondervan KT, Montgomery GW. High-density fine-mapping of a chromosome 10q26 linkage peak suggests association between endometriosis and variants close to CYP2C19. Fertil Steril. 2011 Jun;95(7):2236-40. Epub 2011 Apr 16. PMID: 21497341.

Painter JN, Anderson CA, Nyholt DR, Macgregor S, Lin J, Lee SH, Lambert A, Zhao Z, Roseman F, Guo Q,  Gordon SD, Wallace L, Henders AK, Visscher PM, Kraft P, Martin NG, Morris AP, Treloar SA, Kennedy SH,  Missmer SA, Montgomery GW, Zondervan KT. 2011. Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Nature Genet., 43, 51-4. PMID: 21151130.

Nica AC, Parts L, Glass D, Nisbet J, Barrett A, Sekowska M, Travers M, Potter S, Grundberg E, Small K, Hedman AK, Bataille V, Tzenova BJ, Surdulescu G, Dimas AS, Ingle C, Nestle FO, di Meglio P, Min JL, Wilk A, Hammond CJ, Hassanali N, Yang TP, Montgomery SB, O'Rahilly S, Lindgren CM, Zondervan KT, Soranzo N, Barroso I, Durbin R, Ahmadi K, Deloukas P, McCarthy MI, Dermitzakis ET, Spector TD. 2011. The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study. PLoS Genet, 7, e1002003. PMID: 21304890.

Zondervan KT. 2011. Genetic Association Study Design. In: Analysis of Complex Disease Association Studies. Zeggini & Morris (Eds), Elsevier Academic Press, London, pp 25-48.

ClarkeGM, Anderson CA, PetterssonFH, CardonLR, MorrisAP, Zondervan KT. 2011. Basic statistical analysis in genetic case-control studies. Nature Protoc., 6, 121-33. PMID: 21293453.

2010

Lee SH, Nyholt DR, Macgregor S, Zondervan KT, Montgomery GW, Visscher PM. 2010. A simple and fast two-locus quality control test to detect false positives due to batch effects in genome-wide association studies. Genet. Epidemiol., 34, 854-862. PMID: 21104888.

Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Carola ZM, Speliotes EK, Magi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpelainen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Allen HL, Weyant RJ, Wheeler E, Wood AR, MAGIC, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JRB, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proenca C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich T, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day INM, Dei M, Dorr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJC, Gjesing AP, Grallert H, Graessler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovacs P, Kroemer HK, Krzelj V, Kuusisto J, Kvaloy K, Laitinen J, Lantieri O, Lathrop GM, Lokki ML, Luben RN, Ludwig B, McArdle WL, McCarthy A, Morken MA, Nelis M, Neville MJ, Pare G, Parker AN, Peden JF, Pichler I, Pietilainen KH, Platou CGP, Pouta A, Ridderstrale M, Samani NJ, Saramies J, Sinisalo J, Smit JH, Strawbridge RJ, Stringham HM, Swift AJ, Teder-Laving M, Thomson B, Usala G, van Meurs JBJ, van Ommen GJ, Vatin V, Volpato CB, Wallaschofski H, Walters CB, Widen E, Wild SH, Willemsen G, Witte DR, Zgaga L, Zitting P, Beilby JP, James AL, Kahonen M, Lehtimaki T, Nieminen MS, Ohlsson C, Palmer LJ, Raitakari O, Ridker PM, Stumvoll M, Tonjes A, Viikari J, Balkau B, Ben Shlomo Y, Bergman RN, Boeing H, Smith GD, Ebrahim S, Froguel P, Hansen T, Hengstenberg C, Hveem K, Isomaa B, Jorgensen T, Karpe F, Khaw KT, Laakso M, Lawlor DA, Marre M, Meitinger T, Metspalu A, Midthjell K, Pedersen O, Salomaa V, Schwarz PEH, Tuomi T, Tuomilehto J, Valle TT, Wareham NJ, Arnold AM, Beckmann JS, Bergmann S, Boerwinkle E, Boomsma DI, Caulfield MJ, Collins FS, Eiriksdottir G, Gudnason V, Gyllensten U, Hamsten A, Hattersley AT, Hofman A, Hu FB, Illig T, Iribarren C, Jarvelin MR, Kao WHL, Kaprio J, Launer LJ, Munroe PB, Oostra B, Penninx BW, Pramstaller PP, Psaty BM, Quertermous T, Rissanen A, Rudan I, Shuldiner AR, Soranzo N, Spector TD, Syvanen AC, Uda M, Uitterlinden A, Volzke H, Vollenweider P, Wilson JF, Witteman JC, Wright AF, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, Frayling TM, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, North KE, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, Hirschhorn JN, Assimes TL, Wichmann HE, Thorsteindottir U, van Duijn CM, Stefansson K, Cupples LA, Loos RJF, Barroso I, McCarthy MI, Fox CS, Mohlke KL, Lindgren CM. 2010. Meta-analysis identifies 13 novel loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genet, 42, 949-60. PMID: 20935629.

Anderson CA, PetterssonFH, ClarkeGM, CardonLR, MorrisAP, Zondervan KT. 2010. Data quality control in genetic case-control association studies. Nature Protoc., 5, 1564-73. PMID: 21085122.

Min JL, Barrett A, Watts T, Pettersson FH, Lockstone HE, Lindgren CM, Taylor JM, Allen M, Zondervan KT, McCarthy MI. 2010. Variability of gene expression profiles in human blood and lymphoblastoid cell lines. BMC Genomics. 11:96. PMID: 20141636

Zhuang JJ, Zondervan K, Nyberg F, Harbron C, Jawaid A, Cardon LR, Barratt BJ, Morris AP. 2010. Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group. Genet. Epidemiol. 34(4):319-26. PMID: 20088020

2009

Lin J, Kennedy SH, Svarovsky T, Rogers J, Kemnitz JW, Xu A, Zondervan KT. 2009. High-quality genomic DNA extraction from formalin-fixed and paraffin-embedded samples deparaffinized using mineral oil. Anal.Biochem. 395:265-7. PMID: 19698695

Nnoaham KN, Sivananthan S, Hummelshoj L, Jenkinson C, Webster P, Kennedy SH, Zondervan KT. Multi-center studies of the global impact of endometriosis and the predictive value of associated symptoms. J Endometriosis. 1:36-45. Read Abstract

Pettersson FH, Anderson CA, Clarke GM, Barrett JC, Cardon LR, Morris AP, Zondervan KT. 2009. Marker selection for genetic case-control association studies. Nat.Protoc. 4:743-752. PMID: 19390530

Rogers PA, D'Hooghe TM, Fazleabas A, Gargett CE, Giudice LC, Montgomery GW, Rombauts L, Salamonsen LA, Zondervan KT. 2009. Priorities for endometriosis research: recommendations from an international consensus workshop. Reprod.Sci. 16:335-346. PMID: 19196878

2008

Bennett DA, Xu P, Clarke R, Zondervan K, Parish S, Palmer A, Cardon L, Peto R, Lathrop M, Collins R. 2008. The exon 1-8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population. Eur.J.Hum.Genet. 16:480-486. PMID: 18231128

Bhanoori M, Kameshwari DB, Zondervan KT, Deenadayal M, Kennedy S, Shivaji S. 2008. The endothelial nitric oxide synthase Glu298Asp polymorphism is not a risk factor for endometriosis in south Indian women. Eur.J.Obstet.Gynecol.Reprod.Biol. 139(1):53-8. PMID: 18313829

Montgomery GW, Nyholt DR, Zhao ZZ, Treloar SA, Painter JN, Missmer SA, Kennedy SH, Zondervan KT. 2008. The search for genes contributing to endometriosis risk. Hum.Reprod.Update. 14:447-457. PMID: 18535005

Montgomery GW, Treloar SA, Kennedy SH, Zondervan KT.  2008.  Genetic variation and endometriosis risk. In: Endometriosis 2008. D. Healy & P. Maher (eds). 1st edition. Blackwell Publishing, Oxford, UK.

Sinaii N, Plumb K, Cotton L, Lambert A, Kennedy S, Zondervan K, Stratton P. 2008. Differences in characteristics among 1,000 women with endometriosis based on extent of disease. Fertil.Steril. 89:538-545. PMID: 17498711

2007

Ikuhashi Y, Yoshida S, Kennedy S, Zondervan K, Takemura N, Deguchi M, Ohara N, Maruo T. 2007. Vascular endothelial growth factor +936 C/T polymorphism is associated with an increased risk of endometriosis in a Japanese population. Acta Obstet.Gynecol.Scand. 86(11):1352-1358. PMID: 17963603

Treloar SA, Zhao ZZ, Le L, Zondervan KT, Martin NG, Kennedy S, Nyholt DR, Montgomery GW. 2007. Variants in EMX2 and PTEN do not contribute to risk of endometriosis. Mol.Hum.Reprod. 13:587-594. PMID: 17563403

Zondervan KT and Cardon LR. 2007. Designing candidate gene and genome-wide case-control association studies. Nat.Protoc.     2: 2492-2501. PMID: 17947991

Zondervan KT, Treloar SA, Lin J, Weeks DE, Nyholt DR, Mangion J, Mackay IJ, Cardon LR, Martin NG, Kennedy SH, Montgomery GW. 2007. Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15. Hum.Reprod. 22:717-728. PMID: 17158817

2006

Clarke R, Xu P, Bennett D, Lewington S, Zondervan K, Parish S, Palmer A, Clark S, Cardon L, Peto R, Lathrop M, Collins R. 2006. Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study. PLoS.Genet. 2(7):e107. PMID: 16839190

Grace VM and Zondervan KT. 2006. Chronic pelvic pain in women in New Zealand: comparative well-being, comorbidity, and impact on work and other activities. Health.Care.Women.Int. 27:585-599. PMID: 16844672

Linsell L, Dawson J, Zondervan K, Rose P, Carr A, Randall T, Fitzpatrick R. 2006. Pain and overall health status in older people with hip and knee replacement: a population perspective. J.Public Health (Oxf). 28:267-273. PMID: 15685430

Linsell L, Dawson J, Zondervan K, Rose P, Randall T, Fitzpatrick R, Carr A. 2006. Prevalence and incidence of adults consulting for shoulder conditions in UK primary care; patterns of diagnosis and referral. Rheumatology.(Oxford). 45:215-221. PMID: 16263781

2005

Bhanoori M, Arvind BK, Pavankumar Reddy NG, Lakshmi RK, Zondervan K, Deenadayal M, Kennedy S, Shivaji S. 2005. The vascular endothelial growth factor (VEGF) +405G>C 5'-untranslated region polymorphism and increased risk of endometriosis in South Indian women: a case control study. Hum.Reprod. 20:1844-1849. PMID: 15746194

Zondervan KT, Cardon LR, Kennedy SH, Martin NG, Treloar SA. 2005. Multivariate genetic analysis of chronic pelvic pain and associated phenotypes. Behav.Genet. 35:177-188. PMID: 15685430

Dawson J, Linsell L, Zondervan K, Rose P, Carr A, Randall T, Fitzpatrick R. 2005. Impact of persistent hip or knee pain on overall health status in elderly people: a longitudinal population study. Arthritis Rheum. 53:368-374. PMID: 15934104

Dawson J, Linsell L, Doll H, Zondervan K, Rose P, Carr A, Randall T, Fitzpatrick R. 2005. Assessment of the Lequesne index of severity for osteoarthritis of the hip in an elderly population. Osteoarthritis.Cartilage. 13:854-860. PMID: 16126417

Linsell L, Dawson J, Zondervan K, Rose P, Carr A, Randall T, Fitzpatrick R. 2005. Population survey comparing older adults with hip versus knee pain in primary care. Br.J.Gen.Pract. 55:192-198. PMID: 15808034

Linsell L, Dawson J, Zondervan K, Randall T, Rose P, Carr A, Fitzpatrick R. 2005. Prospective study of elderly people comparing treatments following first primary care consultation for a symptomatic hip or knee. Fam.Pract. 22:118-125.  PMID: 15520033

2004

Babu KA, Rao KL, Reddy NG, Kanakavalli MK, Zondervan KT, Deenadayal M, Singh A, Shivaji S, Kennedy S. 2004. N-acetyl transferase 2 polymorphism and advanced stages of endometriosis in South Indian women. Reprod.Biomed.Online. 9:533-540. PMID: 15588473

Dawson J, Linsell L, Zondervan K, Rose P, Randall T, Carr A, Fitzpatrick R. 2004. Epidemiology of hip and knee pain and its impact on overall health status in older adults. Rheumatology. 43:497-504. PMID: 14762225

Durrant C, Zondervan KT, Cardon LR, Hunt S, Deloukas P, Morris AP. 2004. Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes. Am.J.Hum.Genet. 75:35-43. PMID: 15148658

Grace VM and Zondervan KT. 2004. Chronic pelvic pain in New Zealand: prevalence, pain severity, diagnoses and use of the health services. Aust.N.Z.J.Public Health. 28:369-375. PMID: 15704703

Zondervan KT, Weeks DE, Colman R, Cardon LR, Hadfield R, Schleffler J, Trainor AG, Coe CL, Kemnitz JW, Kennedy SH. 2004. Familial aggregation of endometriosis in a large pedigree of rhesus macaques. Hum.Reprod. 19:448-455. PMID: 14747196

Zondervan KT and Cardon LR. 2004. The complex interplay among factors that influence allelic association. Nat.Rev.Genet. 5:89-100. PMID: 14735120

2002

Zondervan K, Cardon L, Desrosiers R, Hyde D, Kemnitz J, Mansfield K, Roberts J, Scheffler J, Weeks DE, Kennedy S. 2002. The genetic epidemiology of spontaneous endometriosis in the rhesus monkey. Ann.N.Y.Acad.Sci. 955:233-238. PMID: 11949951

Zondervan K, Cardon L, Kennedy S. 2002. Development of a web site for the genetic epidemiology of endometriosis. Fertil.Steril. 78:777. PMID: 12372456

Zondervan KT, Cardon LR, Kennedy SH. 2002. What makes a good case-control study? Design issues for complex traits such as endometriosis. Hum Reprod. 17:1415-1423.  PMID: 12042253

Nakago S, Hadfield RM, Zondervan KT, Mardon H, Manek S, Weeks DE, Barlow DH, Kennedy SH. 2001. Association between endometriosis and N-acetyl Transferase 2 polymorphisms in the UK population. Mol.Hum.Reprod. 7:1079-1083.  PMID: 11675475

2001

Zondervan KT, Yudkin PL, Vessey MP, Jenkinson CP, Dawes MG, Barlow DH, Kennedy SH. 2001. The community prevalence of chronic pelvic pain in women and associated illness behaviour. Br.J.Gen.Pract. 51(468):541-547.  PMID: 11462313

Zondervan KT, Yudkin PL, Vessey MP, Jenkinson CP, Dawes MG, Barlow DH, Kennedy SH. 2001. Chronic pelvic pain in the community: symptomatology, investigations and diagnoses. Am.J.Obstet.Gynecol. 184(6):1149-55. PMID: 11349181

Zondervan KT, Cardon LR, Kennedy SH. 2001. The genetic basis of endometriosis. Curr.Opin.Obstet.Gynecol. 13:309-314. PMID: 11396656

2000

Zondervan K and Barlow DH. 2000. Epidemiology of chronic pelvic pain. Baillieres Best.Pract.Res.Clin.Obstet.Gynaecol. 14:403-414. PMID: 10962634

1999

Zondervan KT, Yudkin PL, Vessey MP, Dawes MG, Barlow DH, Kennedy SH. 1999. Prevalence and incidence in primary care of chronic pelvic pain in women: evidence from a national general practice database. Br.J.Obstet.Gynaecol. 106:1149-1155.  PMID: 10549959

Zondervan KT, Yudkin PL, Vessey MP, Dawes MG, Barlow DH, Kennedy SH. 1999. Patterns of diagnosis and referral in women consulting for chronic pelvic pain in UK primary care. Br.J.Obstet.Gynaecol. 106:1156-1161.  PMID: 10549960