Our high-throughput sequencing facility maintains two of the latest Illumina HiSeq 4000 systems, which we operate in conjunction with three HiSeq 2500’s and two Illumina Miseq systems. Both of these platforms utilise Illumina's proven and widely adopted reversible terminator-based sequencing-by-synthesis chemistry, in combination with innovative scanning technology.
Based on Illumina's BeadArray technology, Agena's MassArray system and the Affymetrix GeneTitan microarray platform, we offer a range of applications to support small-scale and high-throughput studies. Alongside genome-wide association studies and follow-up validation work, we can also perform specific genotyping, methylation assays and gene expression analysis.
The Oxford Genomics Centre is a leading centre for the generation and statistical analysis of genomic data. Our aim is to couple cutting-edge research into the genetic basis of complex disease with the development of statistical methodology and computational tools to help researchers interpret their data.
The Oxford Genomics Centre has completed their protocol evaluation using the TrueMethyl kit from CEGX and will now be offering this form of library preparation and sequencing as a standard service. Epigenetic modification of DNA through the addition a methyl group to cytosine is known to play a role in chromatin remodelling and gene regulation. ...