Dr David Buck

Head of High-Throughput Genomics

 

Research management professional with over 20 years of experience in creating leading and coaching teams of outstanding molecular biologists. This experience has been gained in results-driven environments that have involved complex restructuring, international expansion and implementation of cutting edge technology in the area of DNA sequencing and genetic analysis.  Recognised and accomplished leader with a track record and execution skills that have engendered improved scientific performance, heightened productivity and enhanced internal controls. Strong interpersonal qualities and the desire and skill set needed to succeed in the fast moving, competitive sphere of High Throughput Genomics.

  

Recent publications

Buck, D., Spencer, M.E. & Guest, J.R. Primary structure of Succinyl-CoA Synthetase of Escherichia coli K12 Biochemistry 1987, 24, 6245-6252

Buck, D., Spencer, M.E. & Guest, J.R. Cloning and expression of succinyl-CoA synthetase of Escherichia coli K12 Journal of General Microbiology 1986, 132, 1753-1762

Buck, D., & Guest, J.R. Overexpression and site directed mutagenesis of succinyl-CoA   synthetase of Escherichia coli  K12 and the nucleotide sequence of a gene (g30) that is adjacent to the suc operon. Biochemical Journal 1989, 260, 737-747

Jones, C.E., Brook, J.M., Buck, D., Abell, C. & Smith, A. Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase and overexpression of the enzyme. Journal of Bacteriology, 1993, 175, 2125-2130

Buck, D., Thomas, K., Heathcote, R., Mungall, A., McMurray, A., Baron, L., Hodgson, D., Zhao, S., Bentley, D., Kioshis, P., Coy, J.F., Konecki, D.S., Micklem, G. & Poustka, A.M. Sequencing and analysis of Human Xq28 genomic DNA in the region of RCP/GCP locus. Cytogenetics and Cell Genetics, 1994, 67, 332

Baxendale, S., Abdulla, S., Elgar, G., Buck, D., Berks, M.,Micklem,G., Dubin, R., Bates, G., Brenner, S., beck, S & Lehrach, H. Comparative sequence analysis of the human and pufferfish Huntingtons-disease genes. Nature Genetics 1995,10, 67-76

Naylor, J.A., Buck, D., Green, P., Williamson, H.M., Bentley, D & Gianelli F. The investigation of the factor-VIII intron repeat region (int22h) and the associated inversion junction.  Human Molecular Genetics 1995, 4, 1217-1224

The DNA sequence of human chromosome 22. Nature 1999, 40, 489-495

Nicholas J. Parkinson, Siarhei Maslau, Ben Ferneyhough, Gang Zhang, Lorna Gregory, David Buck, Jiannis Ragoussis, Chris P. Ponting, and Michael D. Fischer. Preparation of high-quality next-generation sequencing libraries from pictogram quantities of target DNA.  Genome Res. 2012, 22(1):125-133