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Dr. Clyde Francks MA DPhil

D.Phil. Genetics of Dyslexia. University of Oxford. 2001.

I am currently working in the pharmaceuticals industry in Italy. I remain a Departmental Visiting Senior Fellow at the Wellcome Trust Centre for Human Genetics (WTCHG), where I maintain active research and collaborations.

Link to Handedness and Schizophrenia webpage

1. Contact details

Dr Clyde Francks

Departmental Visiting Senior Fellow, Wellcome Trust Centre for Human Genetics (WTCHG)  University of Oxford, Roosevelt Drive, Oxford, UK   Email: clyde@well.ox.ac.uk

2. Research Interests

I direct a project with the long term aim of understanding the development and evolution of human brain asymmetry, and how this relates to  human handedness and susceptibility to neuropsychiatric disorders.

I also continue to have an interest in the genetics of dyslexia and attention deficit hyperactivity disorder.

3. Publications

Click here to search PubMed for all journal articles by Clyde Francks

Some recent research papers:

2007:

New! Francks C, Maegawa S, Laurén J, Abrahams BS, Velayos-Baeza A, Medland SE et al. (2007), LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Molecular Psychiatry, August 7 2007 [Abstract from journal]

2002-2006:

Fisher SE, Francks C. Genes, cognition and dyslexia: learning to read the genome. Trends in Cognitive Sciences (2006) Summary

Francks C, Paracchini S, Smith SD, Richardson AJ, Scerri TS, Cardon LR, Marlow AJ, MacPhie IL, Walter J, Pennington BF, Fisher SE, Olson RK, DeFries JC, Stein JF, Monaco AP.  A 77 kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the UK and USA. American Journal of Human Genetics 75: 1046-1058 (2004) Summary

Francks C, DeLisi LE, Shaw SH, Fisher SE, Richardson AJ, Stein JF, Monaco AP. Parent-of-origin effects on handedness and schizophrenia susceptibility on chromosome 2p12-q11. Human Molecular Genetics 12:3225-3230 (2003) Summary

Francks C, Fisher SE, Marlow AJ, MacPhie IL, Taylor KE, Richardson AJ, Stein JF, Monaco AP. Familial and genetic effects on motor coordination, laterality, and reading-related cognition. American Journal of Psychiatry 160: 1970-1977 Correction: 161:185. (2003) Summary

Marlow AJ, Fisher SE, Francks C, MacPhie IL, Cherny SS, Richardson AJ, Talcott JB, Stein JF, Monaco AP, Cardon LR.  Use of multivariate linkage analysis for dissection of a complex cognitive trait. American Journal of Human Genetics 72:561-570 (2003) Summary

Francks C, DeLisi LE, Fisher SE, Laval SH, Rue JE, Stein JF, Monaco AP.  Confirmatory evidence for linkage of relative hand skill to 2p12-q11. American Journal of Human Genetics 72: 499-502 (2003) Summary

Fisher SE, Francks C, McCracken JT, McGough JJ, Marlow AJ, MacPhie IL, Newbury DF, Palmer CGS, Woodward JA, Del’Homme M, Cantwell DP, Nelson SF, Monaco AP, Smalley SL.  A Genome-Wide Scan for Loci Involved in Attention-Deficit/Hyperactivity Disorder (ADHD). American Journal of Human Genetics 70:1183-1196 (2002) Summary

Francks C, Fisher SE, MacPhie IL, Richardson AJ, Marlow AJ, Stein JF, Monaco AP. A genomewide linkage screen for relative hand skill in sibling pairs. American Journal of Human Genetics 70: 800-805 (2002) Summary

Fisher SE*, Francks C*, Marlow AJ, MacPhie IL, Williams DF, Cardon LR, Ishikawa-Brush Y, Talcott JB, Richardson AJ, Gayan J, Olson RK, Pennington BF, Smith SD, DeFries JC, Stein JF, Monaco AP. Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia. Nature Genetics 30: 86-91 (2002) Summary
* Joint authorship.

Francks C, MacPhie IL, Monaco AP. The genetic basis of dyslexia. The Lancet Neurology 1:483-490. (2002) Summary