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Major grants to Strubi investigators

Major grants to Strubi investigators

Updated 21/04/2015

Christian Siebold and Juha Huiskonen in the Division of Structural Biology (Strubi) have been awarded prestigious European Research Council (ERC) consolidator grants each of approximately €2 million. These grants support outstanding researchers who ...

Complex genetic ancestry of Americans

Complex genetic ancestry of Americans

Updated 01/04/2015

Oxford researchers including Simon Myers and George Busby of WTCHG have analysed DNA from 4000 people in Europe, Africa and the Americas and found the genetic fingerprints of the slave trade and colonisation that shaped migrations to the Americas hundreds of years ago.

Who do you think you really are?

Who do you think you really are?

Updated 19/03/2015

The first fine-scale analysis of the population of the UK shows that subtle variations in the genetic make-up of modern Britons reflect the history of their islands’ colonisation by peoples from mainland Europe since the last Ice Age. ‘It has long ...

A cut above: structure shows how enzyme suppresses developmental protein

A cut above: structure shows how enzyme suppresses developmental protein

Updated 27/02/2015

A variety of signalling molecules ensure that the process of development from an undifferentiated ball of cells to an adult of the right size and shape proceeds according to plan. Matthias Zebisch at the Structural Biology Division (STRUBI) in ...

New route to polio vaccine

New route to polio vaccine

Updated 17/02/2015

Dave Stuart, co-director of the Structural Biology Division (STRUBI) at WTCHG, is participating in a new programme to develop a synthetic polio vaccine that mimics the structure of the virus while containing no genetic material.

Genome-wide study strengthens genetic link to obesity

Genome-wide study strengthens genetic link to obesity

Updated 16/02/2015

The largest studies to date of genetic links to obesity and body-fat distribution have discovered more than 140 locations in the genome that play a role in obesity traits. These studies, published in Nature on 11 February 2015, have shed new light ...

New light on genetics of antimalarial drug resistance

New light on genetics of antimalarial drug resistance

Updated 19/01/2015

The largest genome-wide association study to date of the malaria parasite Plasmodium falciparum unveils a complex genetic architecture that enables the parasite to develop resistance to our most effective antimalarial drug, artemisinin. The results ...

NDM excels in REF 2014 exercise

NDM excels in REF 2014 exercise

Updated 18/12/2014

Today’s Research Excellence Framework (REF 2014) results confirm the University of Oxford’s world leading position in medical sciences research. Clinical Medicine ranked top for the overall quality of submissions along with Public Health Service, and Primary Care and Psychology, Psychiatry and Neuroscience.

Top-to-bottom changes in colorectal cancer

Top-to-bottom changes in colorectal cancer

Updated 01/12/2014

Researchers at the WTCHG have discovered a new mechanism that triggers the development of tumours in the large intestine. The work could have major implications for the design of therapeutic strategies against colorectal cancers. The cells that ...

Director's 2001 paper selected as a 'classic'

Director's 2001 paper selected as a 'classic'

Updated 03/11/2014

A paper from 2001 by Centre Director Peter Donnelly has been selected by the American Journal of Human Genetics as one of 10 classic papers published in the 65 years of its history. A special issue containing these papers was distributed at the ...