Dr. Claire Palles, part of the Tomlinson group based at the WTCHG, has been highlighted by the Nuffield Department of Medicine as part of their series of video interviews. Hear more about how Dr. Palles uses whole genome sequencing with the aim of discovering genetic variants that affect susceptibility to colorectal cancer and Barrett’s oesophagus.
Clinicians and researchers are preparing to light Oxford’s Magdalen Tower blue to mark World Diabetes Day – and have invited patients and visitors to then learn more at an open day about the condition at the Churchill Hospital.
Research involving the Tomlinson group has been published in "Cancer Cell" looking at the effect of a gene IDH1R132H in the development of tumours in glial cells, such as the brain. They found that expression of IDH1R132H in the adult mouse brain causes features of glioma development, and a gene expression profile overlapping that of human glial tumours.
An international collaboration, including researchers jointly from the Wellcome Trust Centre of Human Genetics and the Wellcome Trust Sanger Institute, carried out a genome-wide association study on approximately 300 Plasmodium falciparum samples from Cambodia to study the genetic basis behind piperaquine resistance.
New research finds genetic differences that help to explain why some babies are born bigger or smaller than others. The research, led by WTCHG researchers, also reveals how genetic differences provide an important link between an individual’s early growth and their chances of developing conditions such as type 2 diabetes or heart disease in later life.
Sandy Douglas from the Jenner institute features in this Medical Sciences Division podcast on viruses, released to mark World Rabies Day. He discusses the first rabies vaccine and his new strategy to fight rabies using an adenovirus. Other scientists from the Division talk about using viruses to understand how the brain work.
Oxford becomes the first British university ever to occupy top position in the global table, which judges the performance of 980 universities across 79 countries. Oxford’s top ranking reflects its all-round strength in contemporary research and teaching.
Professor Sir Peter Ratcliffe has won one of the most prestigious prizes in medicine. The Lasker Awards recognise contributions that have allowed major advances in the understanding, diagnosis, treatment, and prevention of human disease. Professor Ratcliffe is to receive the prizes for his work understanding the mechanisms by which cells sense and signal hypoxia (low oxygen levels)
There has been considerable interest about the extent to which genetic factors interact with environmental and lifestyle factors in human traits. Alex Young and colleagues in Peter Donnelly’s group at the Wellcome Trust Centre for Human Genetics ...
WTCHG researchers, as part of an international study, have helped to uncover new genetic evidence of how the benefits of the world's most commonly used Type 2 diabetes drug may vary between individuals.