Dr Keith J Morris

Keith

Keith was awarded a 2:1 honours BSc degree in Zoology (1977) from Liverpool University's Faculty of Biology, and a Masters MSc degree in Environmental Pollution Control (1978) and a PhD in Atmospheric Aerosol Science (1984), both from Leeds University's Faculty of Engineering. Keith's PhD studies involved the characterisation of urban and rural atmospheric aerosols, with particular regard to modelling airborne pollutants. In 1984 Keith moved to the MRC Radiobiology Unit, Harwell, where he investigated the dosimetric implications of inhaled actinide particles. In 1989, Keith transferred to the UKAEA's Biomedical Research Department at the Harwell Laboratory, working on lung micro-dosimetry studies and the in-vivo durability of man made mineral fibres. From 2001 to 2006, Keith ran the UCL Institute of Ophthalmology's modern optical microscopy live cell, laser micro-dissection and confocal imaging facilities.

In 2007 he joined the WTCHG's Cellular Imaging Core, where he manages the day to day running of the Centre's microscopy imaging facilities. In addition Keith is involved in centre based collaborative projects, providing support for live-cell imaging, immunofluorescence, cytological techniques, and microscopical analysis. Keith is also a STEM Ambassador for the schools science outreach program in Oxfordshire, and in 2001 he was awarded NQT secondary school teacher status after completing a PGCE in Secondary School Science.

Keith has extensive research experience in modern microscopic methods, histological techniques, image analysis, image processing, computer programming, and PC based imaging workstations. His hobbies include film/digital photography, graphics design, and personal computers.

Keith invertFISH
A 'chromosome painting' FISH experiment     

 

Selected Publications

De Colibus L, Sonnen AF, Morris KJ, Siebert CA, Abrusci P, Plitzko J, Hodnik V, Leippe M, Volpi E, Anderluh G, Gilbert RJ. 2012. Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition. Structure, 20 (9), pp. 1498-1507. | Read more

YUSUF M, LEUNG K, MORRIS K J, VOLPI EV. 2012. Comprehensive cytogenomic profile of the in vitro neuronal model SH-SY5Y. Neurogenetics  12 (1), pp. 63-70. | Read More

PRAPER T, SONNEN AF-P, KLADNIK A, ANDRIGHETTI AO, VIERO G, MORRIS KJ, VOLPI E, LUNELLI L, SERRA MD, FROELICH CJ, GILBERT RJC, ANDERLUH G. 2011. Perforin activity at membranes leads to invaginations and vesicle formation. Proceedings of the National Academy of Sciences of the United States of America, 108 (52), pp. 21016-21021. | Read more

WILKES SE, MORRIS KJ, BHATTACHARYA SS, WARREN MJ, HUNT DM. 2006. A study of the nuclear trafficking of the splicing factor protein PRPF31 linked to autosomal dominant retinitis pigmentosa (ADRP). Biochemica et Biophysica Acta 1762, pp. 304-311. | Read more

ZHANG L, MORRIS KJ, NG YC. 2006. Fibre type-specific immunostaining of the Na+, K+-ATPase subunit isoforms in skeletal muscle: age-associated differential changes. Biochemica et Biophysica Acta: The Molecular Basis of Disease 1762, pp 783-793.

MORRIS KJ. 1995. Chapter 10: Modern microscopic methods of bioaerosol analysis. Bioaerosols Handbook, Eds. Cox CS, Wathes CM,  pp. 285-316, CRC Press Inc., USA. | Read more

EASTES WL, MORRIS KJ, MORGAN A, LAUNDER KA, COLLIER CG, DAVIS JA, MATTSON SM,  HADLEY JG. 1995. Dissolution of glass fibres in the lung following intra-tracheal instillation. Inhal. Tox. 7, pp. 197-213.

MORGAN A, MORRIS KJ, DAVIS JA, MATTSON SM. 1994. Effect of chemical composition on the solubility of glass fibre in vivo and in vitro. Ann. Occ Hyg. 38, pp. 609-617.

MORRIS KJ, BARKER CL, BATCHELOR AL,  KHANNA P. 1991. Temporal variation in the micro-distribution of enriched uranium dioxide particles deposited in the left lung.  Radiat. Prot. Dosimet. 38, pp. 221-227.

MORRIS KJ, KHANNA P, BATCHELOR AL. 1990. Long-term clearance of inhaled enriched uranium dioxide particles from the pulmonary region of the lung. Health Phys. 58, pp. 477-485.

MORRIS KJ, TOWNSEND KMS., A.L. BATCHELOR AL. 1989. Studies of alveolar cell morphometry and mass clearance in the lung following inhalation of an enriched uranium dioxide aerosol. Radiat. Environ. Biophys. 28, pp. 141-154.

MORRIS KJ, BATCHELOR AL. 1988. The simultaneous imagining of boronated tissue sections and the location of fissionable actinide particles in CR-39 solid state track detector, utilising a neutron-induced autoradiographic technique. Phys Med Biol 33 (10), pp. 1195-1203.