CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools. Mamm Genome, pp. 1-15. Article
Human genetics as a model for target validation: finding new therapies for diabetes. Diabetologia, 60 (6), pp. 960-970. Article
In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment. Data Brief, 12, pp. 676-691. Article
Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine. Sci Rep, 7, pp. 46621. Article
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase. Sci Transl Med, 8 (340), pp. 340ra74. Article
Urgent improvements needed to diagnose and manage Lynch syndrome. BMJ, 356, pp. j1388. ArticleMore publications
A study co-led by Dr Ben Davies using CRISPR-Cas9 genome editing tools to explore the function of non-coding DNA and its contribution to defining cell identity has been published today in Nature Cell Biology.
Proteins found in tick saliva could be used to treat a potentially fatal form of heart disease, according to new research by the Bhattacharya group
Centre PI Prof Krina Zondervan has been published today in Nature Communications as part of a group investigating new genetic sites associated with endometriosis.