The Wellcome funded four year DPhil Programme in Genomic Medicine and Statistics trains future scientific leaders who will work at the cutting edge of genomics in biomedical research and enable effective delivery into the clinic. The application cycle for entry in 2018 opens 1 September 2017.
Vaccines against Ebola virus. Vaccine. Article
Using Genomic Information to Guide Ibrutinib Treatment Decisions in Chronic Lymphocytic Leukaemia: A Cost-Effectiveness Analysis. Pharmacoeconomics, 35 (8), pp. 845-858. Article
STOCHASTIC MODELLING AND INFERENCE IN ELECTRONIC HOSPITAL DATABASES FOR THE SPREAD OF INFECTIONS: CLOSTRIDIUM DIFFICILE TRANSMISSION IN OXFORDSHIRE HOSPITALS 2007-2010 ANNALS OF APPLIED STATISTICS, 11 (2), pp. 655-679. Article
CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools. Mamm Genome, 28 (7-8), pp. 247-261. ArticleMore publications
A new study from the JDRF/Wellcome Diabetes and Inflammation Laboratory has identified several novel disease associated candidate genes, which are differentially expressed during T cell activation, using a genome-wide approach to identify contacts between promoters and regulatory sequences containing disease-associated SNPs.
Although naive human T cells underpin the adaptive arm of the immune system, Marcin Pekalski and colleagues have discovered that these cells express innate complement receptors, opening a new avenue in microbial defence in newborn children.
A study co-led by Dr Ben Davies using CRISPR-Cas9 genome editing tools to explore the function of non-coding DNA and its contribution to defining cell identity has been published today in Nature Cell Biology.