Guadalupe Polanco

Guadalupe is working on different applications of the next generation sequencing techniques. She helped to establish the Roche 454 sequencing technology within the Group and now works within the library preparation team as part of the Sequencing facility which is based on the Illumina HiSeq platform.

Recent Publications

Vickaryous N, Polanco-Echeverry G, Morrow S, Suraweera N, Thomas H, Tomlinson I, Silver A. (2008) Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome. Br J Cancer 99(10): 1726-8. Epub 2008 Oct 21 [PMID: 18941465]

Patel H, Polanco-Echeverry G, Segditsas S, Volikos E, McCart A, Lai C, Guenther T, Zaitoun A, Sieber O, Ilyas M, Northover J, Silver A. (2007) Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma. Int J Cancer 121(12): 2668-73 [PMID: 17721920]

Carvajal-Carmona LG, Howarth KM, Lockett M, Polanco-Echeverry GM, Volikos E, Gorman M, Barclay E, Martin L, Jones AM, Saunders B, Guenther T, Donaldson A, Paterson J, Frayling I, Novelli MR, Phillips R, Thomas HJ, Silver A, Atkin W, Tomlinson IP. (2007) Molecular classification and genetic pathways in hyperplastic polyposis syndrome. J Pathol. 212(4): 378-85 [PMID: 17503413]

Will O, Carvajal-Carmona LG, Gorman P, Howarth KM, Jones AM, Polanco-Echeverry GM, Chinaleong JA, Günther T, Silver A, Clark SK, Tomlinson I. (2007) Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer. Gastroenterology 132(2): 527-30. Epub 2006 Nov 29 [PMID: 17258725]

Suraweera N, Haines J, McCart A, Rogers P, Latchford A, Coster M, Polanco-Echeverry G, Guenther T, Wang J, Sieber O, Tomlinson I, Silver A. (2006) Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice. Hum Mol Genet. 15(23): 3429-35. Epub 2006 Oct 24 [PMID: 17062636]

Herzberg I, Jasinska A, García J, Jawaheer D, Service S, Kremeyer B, Duque C, Parra MV, Vega J, Ortiz D, Carvajal L, Polanco G, Restrepo GJ, López C, Palacio C, Levinson M, Aldana I, Mathews C, Davanzo P, Molina J, Fournier E, Bejarano J, Ramírez M, Ortiz CA, Araya X, Sabatti C, Reus V, Macaya G, Bedoya G, Ospina J, Freimer N, Ruiz-Linares A. (2006) Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34. Hum Mol Genet. 15(21): 3146-53. Epub 2006 Sep 19 [PMID: 16984960]

Keywords:

454 Genome Sequencer FLX, next generation sequencing.