Dyslexia

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Overview

What is dyslexia?

Developmental dyslexia is also known as specific reading disability (ICD classification).  It is the most common of the childhood learning disorders. Children affected with developmental dyslexia have difficulty learning to read and spell, despite adequate intelligence and educational opportunity, and in the absence of any profound sensory or neurological impairment. Reading deficits can have a major influence on the cognitive, emotional and social development of affected individuals.

Links for further reading on dyslexia 

Is dyslexia genetic? 

The familial clustering of reading and spelling disability was first noted at the turn of the century. However, the fact that dyslexia tends to run in families does not necessarily implicate genetic factors, since familial clustering can also be caused by shared family environment. The strongest evidence of genetic influences on dyslexia has come from twin studies, which compare the concordance of the trait in identical (monozygotic) and non-identical (dizygotic) twin pairs.

A large-scale twin-study based in Colorado, USA has found that the heritability of dyslexia (i.e. the proportion of trait variability that can be explained by genetic factors) is more than 50%.

What are our goals?

- We aim to track down the genes that are involved in developmental dyslexia.  

- We are searching for the specific genetic variants that increase the risk of developing dyslexia.

- We use state-of-the-art technology to analyse hundreds of genetic markers in large numbers of families with children affected by dyslexia.

 

Read here for our current research.  

For all enquiries, please contact Dr Antonio Velayos Baeza at avelayos@well.ox.ac.uk