Personalised Medicine

Personalised medicine encompasses all aspects of healthcare from health promotion, risk stratification and screening through to clinical diagnosis, prognosis and treatment. It is typically used to refer to the application of new technologies to tailor healthcare, including imaging, biomarkers, and often genetics on which we currently have a focus. For example, instead of a population-based 'one size fits all' approach, applying the knowledge acquired from sequencing human and pathogen genomes will allow patients to be matched to the best therapy, so that a patient is treated with the right drug at the right dose at the right time.

Rapid advances in genetics research and the declining cost of new sequencing technologies is enabling information from genomics research to be targeted to healthcare. It has the potential to transform our approach to individual, population and global health by reducing costs and increasing the efficacy of disease prevention and treatment. Translating this knowledge from concept to clinic will require further basic science, clinical and policy-based research, and continued exploration of the ethical, legal and societal implications.

Examples of Personalised Medicine in Oxford

E Barnes

STOP HCV

www.stop-hcv.ox.ac.uk/home
Prof Ellie Barnes, Consortium Lead STOP-HCV.
Profile: http://www.ndm.ox.ac.uk/principal-investigators/researcher/ellie-eleanor-barnes
Contact:  Dr. Emma Hudson; Project Manager. e-mail; emma.hudson@ndm.ox.ac.uk  
Click here to read about Prof Ellie Barnes' research

 

R Banerjee

Perspectum Diagnostics

www.perspectum-diagnostics.com
Dr Rajarshi Banerjee, Chief Executive and Founder of Perspectum Diagnostics
Profile: http://perspectum-diagnostics.com/about-pd/our-team/
Contact: Matt Kelly, Head of Innovation; matt.kelly@perspectum-diagnostics.com
Click here to read about Dr Rajarshi Banerjee's research

 

S Wordsworth

Genomics England Health Economic GeCIP

Dr Sarah Wordsworth, Lead for the Health Economics Genomics England Clinical Interpretation Partnership (GeCIP) of the 100,000 Genomes Project
Profile http://www.herc.ox.ac.uk/team/sarah-wordsworth
Contact: sarah.wordsworth@dph.ox.ac.uk
Click here to read about Dr Sarah Wordsworth's research

Further Reading

The links below will give further insight into what is meant by Personalised Medicine. The list is deliberately not exhaustive, nor necessarily representative.

NIH Precision medicine
Mayo Clinic Personalized medicine and pharmacogenomics  
Genomics England The 100,000 Genomes Project
White House So what is Precision Medicine?
Stanford University Precision Health
Cancer Research UK Stratified Medicine Programme
PHG Making Science Work for Health