Work Summary:

My research background is in genetics and molecular biology; my PhD thesis was on the adaptation of Arabidopsis and I maintain an active interest in this field. After my PhD I moved into statistical genetics, and am now part of the data analysis team for the second Wellcome Trust Case Control Consortium (WTCCC2). We are working towards identifying the genes underlying fifteen heritable phenotypes (largely common diseases) through an international collaborative project involving thousands of case genotypes and a set of 6000 common controls from the 1958 Birth Cohort and the NBS data set. We are working on several interesting statistical challenges including coping with population stratification and handling association tests involving multiple phenotypes.

Publications:

Strange A, et al. (in prep) QTL determining flowering time and vernalization response in Arabidopsis from diverse habitats.

Strange A. (2008) 11th Congress of the European Society for Evolutionary Biology. Genetics Society News 58

Rudall PJ, Strange A, Cunnif J, Cheek M. (2007) Floral Anatomy of Kupea martinetugei (Triuridaceae). Kew Bulletin 62: 287-292

Strange A, Rudall PJ, Prychid CJ. (2004) Comparative floral anatomy of Pontederiaceae. Botanical Journal of the Linnean Society. 144: 395-408

Research Areas:

Data analysis in genome wide association studies, adaptation to environment, and the role of model organisms.

Keywords

• GWAS
• WTCCC2