2014

Loss of Y chromosome shortens men's lives

Loss of Y chromosome shortens men's lives

Updated 02/05/2014

WTCHG researcher Cecilia Lindgren and former Centre member Andrew Morris have contributed to a study led by scientists at the University of Uppsala and published in Nature Genetics, showing that older men who lose the Y chromosome from a large proportion of their peripheral blood cells have shorter lifespans and an increased cancer risk.

Whole-genome sequencing in bladder cancer

Whole-genome sequencing in bladder cancer

Updated 29/04/2014

For the first time a team at the WTCHG, working with colleagues at Oxford’s CRUK Cancer Centre and elsewhere, has used high-depth, whole-genome sequencing to search for genetic variants in tumours of the bladder. The molecular markers they have ...

New structure for molecular 'hole punch'

New structure for molecular 'hole punch'

Updated 24/04/2014

Researchers in the Structural Biology Division at WTCHG (STRUBI) have discovered how a family of protein molecules deploys hairpin-like structures to punch holes in cell membranes. Robert Gilbert and his colleagues describe how one family of these proteins forms pores of different sizes, with implications for understanding a host of biological processes.

New genomics technologies

New genomics technologies

Updated 17/04/2014

The High-Throughput Genomics group at the WTCHG has recently taken delivery of two new genomics platforms. The Affymetrix GeneTitan offers a fast, automated route to search for genetic variations, or SNPs, that have some association with disease. ...

Boat race victory for WTCHG students

Boat race victory for WTCHG students

Updated 08/04/2014

Two graduate students from the Wellcome Trust Centre for Human Genetics were among the victorious BNY Mellon Boat Race crew that defeated Cambridge by 11 lengths in 18min 36 secs on Sunday 6 April. Malcolm Howard, who is the current President of ...

Malaria research highlighted

Malaria research highlighted

Updated 31/03/2014

The latest issue of Mosaic, the Wellcome Trust's new weekly online magazine exploring the science of life, features the work of Dominic Kwiatkowski's group in an article by Ed Yong on the problem of artemisin-resistant malaria parasites on the border between Thailand and Cambodia.

Dianne Newbury at SET for Britain

Dianne Newbury at SET for Britain

Updated 19/03/2014

Dr Dianne Newbury presented her research on specific language impairment on Robinson Crusoe Island at the annual SET for Britain event at the House of Commons on Monday 17 March.

Science in your world

Science in your world

Updated 17/03/2014

WTCHG DPhil students Eamon Byrne, Katie Burnham and Anna Sanniti, and post-doc Erika Kvikstad, joined a team of staff and students from the Nuffield Department of Medicine in Bonn Square as they entertained some of the 5000 people who turned out for 'Science in Your World', the launch of the Oxfordshire Science Festival on 8 March.

Study tracks effects of immune activity across the genome

Study tracks effects of immune activity across the genome

Updated 05/03/2014

A broad range of common diseases, such as inflammatory bowel disease, rheumatoid arthritis and cancer, are associated with variants in the genome sequence that regulate the expression of genes involved in the immune system. In the course of ...

Peter Donnelly speaks on genetics in Australia

Peter Donnelly speaks on genetics in Australia

Updated 20/02/2014

On Thursday 13 February the WTCHG Director Peter Donnelly gave a lecture in the 'Big Ideas Under the Dome' series at the State Library of Victoria in Melbourne, Australia. His title was 'The Genetic Revolution: How genetics could transform ...